Imaging Anatomy of the Human Brain


Book Description

An Atlas for the 21st Century The most precise, cutting-edge images of normal cerebral anatomy available today are the centerpiece of this spectacular atlas for clinicians, trainees, and students in the neurologically-based medical and non-medical specialties. Truly an "atlas for the 21st century," this comprehensive visual reference presents a detailed overview of cerebral anatomy acquired through the use of multiple imaging modalities including advanced techniques that allow visualization of structures not possible with conventional MRI or CT. Beautiful color illustrations using 3-D modeling techniques based upon 3D MR volume data sets further enhances understanding of cerebral anatomy and spatial relationships. The anatomy in these color illustrations mirror the black and white anatomic MR images presented in this atlas. Written by two neuroradiologists and an anatomist who are also prominent educators, along with more than a dozen contributors, the atlas begins with a brief introduction to the development, organization, and function of the human brain. What follows is more than 1,000 meticulously presented and labelled images acquired with the full complement of standard and advanced modalities currently used to visualize the human brain and adjacent structures, including MRI, CT, diffusion tensor imaging (DTI) with tractography, functional MRI, CTA, CTV, MRA, MRV, conventional 2-D catheter angiography, 3-D rotational catheter angiography, MR spectroscopy, and ultrasound of the neonatal brain. The vast array of data that these modes of imaging provide offers a wider window into the brain and allows the reader a unique way to integrate the complex anatomy presented. Ultimately the improved understanding you can acquire using this atlas can enhance clinical understanding and have a positive impact on patient care. Additionally, various anatomic structures can be viewed from modality to modality and from multiple planes. This state-of-the-art atlas provides a single source reference, which allows the interested reader ease of use, cross-referencing, and the ability to visualize high-resolution images with detailed labeling. It will serve as an authoritative learning tool in the classroom, and as an invaluable practical resource at the workstation or in the office or clinic. Key Features: Provides detailed views of anatomic structures within and around the human brain utilizing over 1,000 high quality images across a broad range of imaging modalities Contains extensively labeled images of all regions of the brain and adjacent areas that can be compared and contrasted across modalities Includes specially created color illustrations using computer 3-D modeling techniques to aid in identifying structures and understanding relationships Goes beyond a typical brain atlas with detailed imaging of skull base, calvaria, facial skeleton, temporal bones, paranasal sinuses, and orbits Serves as an authoritative learning tool for students and trainees and practical reference for clinicians in multiple specialties




Brain Connectivity Analysis: Investigating Brain Disorders


Book Description

In the last few years, advances in human structural and functional neuroimaging (fMRI, PET, EEG/MEG) have resulted in an explosion of studies investigating the anatomical and functional connectivity between different regions of the brain. More and more studies have employed resting and task-related connectivity analyses to assess functional interactions, and diffusion-weighted tractography to study white matter organization. Many of these studies have addressed normal human function, but recently, a number of investigators have turned their attention to examining brain disorders. The study of brain disorders is a complex endeavor; not only does it require understanding the normal brain, and the regions involved in a particular function, but also it needs a deeper understanding of brain networks and their dynamics. This Research Topic will provide the scientific community with an overview of how to apply connectivity methods to study brain disease, and with perspectives on what are the strength and limitations of each modality. For this Research Topic, we solicit both reviews and original research articles on the use of brain connectivity analysis, with non-human or human models, to explore neurological, psychiatric, developmental and neurodegenerative disorders from a system perspective. Connectivity studies that have focused on one or more of the following will be of particular interest: (1) detection of abnormal functional/structural connectivity; (2) neural plasticity, assessed by changes in connectivity, in patients with brain disorders; (3) assessment of therapy using connectivity measures; (4) relation of connectivity changes to behavioral changes.




Neurogenetics, Part II


Book Description

Neurogenetics, Part II, Volume 148, the latest release in the Handbook of Clinical Neurology, provides the latest information on the genetic methodologies that are having a significant impact on the study of neurological and psychiatric disorders. Using genetic science, researchers have identified over 200 genes that cause or contribute to neurological disorders. Still an evolving field of study, defining the relationship between genes and neurological and psychiatric disorders is expected to dramatically grow in scope. Part II builds on the foundation of Part I, expanding the coverage to dementias, paroxysmal disorders, neuromuscular disorders, white matter and demyelination diseases, cerebrovascular diseases, adult psychiatric disorders and cancer and phacomatoses. - Contains comprehensive coverage of neurogenetics - Details the latest science and its impact on our understanding of neurological, psychiatric disorders - Presents a focused reference for clinical practitioners and the neuroscience/neurogenetics research community




MRI Atlas of the Infant Rat Brain


Book Description

MRI Atlas of the Infant Rat Brain: Brain Segmentation features an entirely new coronal, sagittal and horizontal set of tissue cut in regular 9 μm intervals with accompanying photographs of MRI data and color drawings of selected brain regions in the three planes. The use of the single brain allows for greater consistency between sections, while color masking offers advances in manual segmentation techniques with increased refinement in the definition of brain areas. Readers will benefit from uniform and consistent manual tissue segmentation of MRI data in an infant rat brain. This volume provides readers the first infant rat brain MRI atlas and a valuable resource in research analyses of the developing brain for structural and functional MRI analyses. - Provides a one-of-a-kind neuroanatomical reference for the infant rat brain based on MRI acquisition at 2 weeks of age - Covers 31 coronal sections of a single rat brain, allowing for better consistency and delineations of the structural outlines - Illustratively represents a 3D view of the brain and its gross structures for the ease of visual learning - Presents 31 coronal sections of a single rat brain - Includes an eBook in PDF version that is also available for improved digital readability, thus allowing for printing at different magnifications




Control of Ovulation


Book Description

Control of Ovulation discusses the general principles and practical applications of ovulation control. The book presents 25 papers that cover the basic research practices and practicalities of ovulation control. The materials are grouped according to their respective themes. The first three parts cover the hypothalamus, pituitary gland, and ovary, respectively. The remaining papers discuss concerns regarding the applications of ovulation control, such as ovulation failure; diagnosis of ovulatory disorders; and the induction and synchronization of ovulation. The text will be of great use to practitioners of obstetrics and gynecology in both human and veterinary medicine.




Brain Mapping


Book Description

Brain Mapping: A Comprehensive Reference, Three Volume Set offers foundational information for students and researchers across neuroscience. With over 300 articles and a media rich environment, this resource provides exhaustive coverage of the methods and systems involved in brain mapping, fully links the data to disease (presenting side by side maps of healthy and diseased brains for direct comparisons), and offers data sets and fully annotated color images. Each entry is built on a layered approach of the content – basic information for those new to the area and more detailed material for experienced readers. Edited and authored by the leading experts in the field, this work offers the most reputable, easily searchable content with cross referencing across articles, a one-stop reference for students, researchers and teaching faculty. Broad overview of neuroimaging concepts with applications across the neurosciences and biomedical research Fully annotated color images and videos for best comprehension of concepts Layered content for readers of different levels of expertise Easily searchable entries for quick access of reputable information Live reference links to ScienceDirect, Scopus and PubMed




The Neuroscience of Autism Spectrum Disorders


Book Description

Autism is no longer considered a rare disease, and the Center for Disease Control now estimates that upwards of 730,000 children in the US struggle with this isolating brain disorder. New research is leading to greater understanding of and ability to treat the disorder at an earlier age. It is hoped that further genetic and imaging studies will lead to biologically based diagnostic techniques that could help speed detection and allow early, more effective intervention. Edited by two leaders in the field, this volume offers a current survey and synthesis of the most important findings of the neuroscience behind autism of the past 20 years. With chapters authored by experts in each topic, the volume explores etiology, neuropathology, imaging, and pathways/models. Offering a broad background of ASDs with a unique focus on neurobiology, the volume offers more than the others on the market with a strictly clinical focus or a single authored perspective that fails to offer expert, comprehensive coverage. Researchers and graduate students alike with an interest in developmental disorders and autism will benefit, as will autism specialists across psychology and medicine looking to expand their expertise. - Uniquely explores ASDs from a neurobiological angle, looking to uncover the molecular/cellular basis rather than to merely catalog the commonly used behavioral interventions - Comprehensive coverage synthesizes widely dispersed research, serving as one-stop shopping for neurodevelopmental disorder researchers and autism specialists - Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available




Handbook of Stress and the Brain Part 1: The Neurobiology of Stress


Book Description

The Handbook of Stress and the Brain focuses on the impact of stressful events on the functioning of the central nervous system; how stress affects molecular and cellular processes in the brain, and in turn, how these brain processes determine our perception of and reactivity to, stressful challenges - acutely and in the long-run. Written for a broad scientific audience, the Handbook comprehensively reviews key principles and facts to provide a clear overview of the interdisciplinary field of stress. The work aims to bring together the disciplines of neurobiology, physiology, immunology, psychology and psychiatry, to provide a reference source for both the non-clinical and clinical expert, as well as serving as an introductory text for novices in this field of scientific inquiry. Part 1 addresses basic aspects of the neurobiology of the stress response including the involvement of neuropeptide, neuroendocrine and neurotransmitter systems and its corollaries regarding gene expression and behavioural processes such as cognition, motivation and emotionality. * Provides an overview of recent advances made in stress research * Includes timely discussion of stress and its effect on the immune system * Presents novel treatment strategies targeting brain processes involved in stress processing and coping mechanisms




A Combined MRI and Histology Atlas of the Rhesus Monkey Brain in Stereotaxic Coordinates


Book Description

A Combined MRI and Histology Atlas of the Rhesus Monkey Brain in Stereotaxic Coordinates, Second Edition maps the detailed architectonic subdivisions of the cortical and subcortical areas in the macaque monkey brain using high-resolution magnetic resonance (MR) images and the corresponding histology sections in the same animal. This edition of the atlas is unlike anything else available as it includes the detailed cyto- and chemoarchitectonic delineations of the brain areas in all three planes of sections (horizontal, coronal, and sagittal) that are derived from the same animal. This is a significant progress because in functional imaging studies, such as fMRI, both the horizontal and sagittal planes of sections are often the preferred planes given that multiple functionally active regions can be visualized simultaneously in a single horizontal or sagittal section. This combined MRI and histology atlas is designed to provide an easy-to-use reference for anatomical and physiological studies in macaque monkeys, and in functional-imaging studies in human and non-human primates using fMRI and PET. - The first rhesus monkey brain atlas with horizontal, coronal, and sagittal planes of sections, derived from the same animal - Shows the first detailed delineations of the cortical and subcortical areas in horizontal, coronal, and sagittal plane of sections in the same animal using different staining methods - Horizonal series illustrates the dorsoventral extent of the left hemisphere in 47 horizontal MRI and photomicrographic sections matched with 47 detailed diagrams (Chapter 3) - Coronal series presents the full rostrocaudal extent of the right hemisphere in 76 coronal MRI and photomicrographic sections, with 76 corresponding drawings (Chapter 4) - Sagittal series shows the complete mediolateral extent of the left hemisphere in 30 sagittal MRI sections, with 30 corresponding drawings (Chapter 5). The sagittal series also illustrates the location of different fiber tracts in the white matter - Individual variability - provides selected cortical and subcortical areas in three-dimensional MRI (horizontal, coronal, and sagittal MRI planes). For comparison, it also provides similar areas in coronal MRI section in six other monkeys. (Chapter 6) - Vasculature - indicates the corresponding location of all major blood vessels in horizontal, coronal, and sagittal series of sections - Provides updated information on the cortical and subcortical areas, such as architectonic areas and nomenclature, with references, in chapter 2 - Provides the sterotaxic grid derived from the in-vivo MR image




Progress in Episodic Memory Research


Book Description

Episodic memory refers to the ability to remember personal experiences in terms of what happened and where and when it happened. Humans are also able to remember the specific perceptions, emotions and thoughts they had during a particular experience. This highly sophisticated and unique memory system is extremely sensitive to cerebral aging, neurodegenerative and neuropsychiatric diseases. The field of episodic memory research is a continuously expanding and fascinating area that unites a broad spectrum of scientists who represent a variety of research disciplines including neurobiology, medicine, psychology and philosophy. Nevertheless, important questions still remain to be addressed. This research topic on the Progress in Episodic Memory Research covers past and current directions in research dedicated to the neurobiology, neuropathology, development, measurement and treatment of episodic memory.




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