Androgens II and Antiandrogens
Author :
Publisher :
Page : 625 pages
File Size : 15,58 MB
Release : 1974
Category : Androgens
ISBN : 9780387068831
Author :
Publisher :
Page : 625 pages
File Size : 15,58 MB
Release : 1974
Category : Androgens
ISBN : 9780387068831
Author : Carmen Avendaño
Publisher : Elsevier
Page : 767 pages
File Size : 41,88 MB
Release : 2015-06-11
Category : Science
ISBN : 0444626670
Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While these therapies are in their infancy, they hold promise of more effective therapies with fewer side effects. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a sorely needed update from the point of view of medicinal chemistry and drug design. - Presents information in a clear and concise way using a large number of figures - Historical background provides insights on how the process of drug discovery in the anticancer field has evolved - Extensive references to primary literature
Author : Philippa D. Darbre
Publisher : Academic Press
Page : 390 pages
File Size : 44,29 MB
Release : 2015-03-21
Category : Medical
ISBN : 0128011203
Endocrine Disruption and Human Health starts with an overview of what endocrine disruptors are, the issues surrounding them, and the source of these chemicals in the ecosystem. This is followed by an overview of the mechanisms of action and assay systems. The third section includes chapters written by specialists on different aspects of concern for the effects of endocrine disruption on human health. Finally, the authors consider the risk assessment of endocrine disruptors and the pertinent regulation developed by the EU, the US FDA, as well as REACH and NGOs. The book has been written for researchers and research clinicians interested in learning about the actions of endocrine disruptors and current evidence justifying concerns for human health but is useful for those approaching the subject for the first time, graduate students, and advanced undergraduate students. - Provides readers with access to a range of information from the basic mechanisms and assays to cutting-edge research investigating concerns for human health - Presents a comprehensive, translational look at all aspects of endocrine disruption and its effects on human health - Offers guidance on the risk assessment of endocrine disruptors and current relevant regulatory considerations
Author : Luciano Martini
Publisher : Raven Press (ID)
Page : 406 pages
File Size : 11,13 MB
Release : 1977
Category : Nature
ISBN :
Author : John Bancroft
Publisher :
Page : 745 pages
File Size : 13,44 MB
Release : 1989
Category : Medical
ISBN : 9780443034558
This is an updated multidisciplinary and scholarly account of the determinants of human sexuality including sexual development, anatomy and physiology, biochemistry and endocrinology of sexual behaviour in addition to sociological and psychological aspects.
Author : Leo Plouffe, Jr
Publisher : Cambridge University Press
Page : 261 pages
File Size : 34,61 MB
Release : 2015-06-25
Category : Medical
ISBN : 1316298876
A practical approach to the field of androgen excess or deprivation in women's health. The content includes multiple viewpoints on the most common disorders in this class, such as polycystic ovary disease, hirsutism and menopausal issues. Each chapter provides a combination of long-lasting clinical principles in the diagnosis and management of these patients along with a state-of-the-art review. This text takes an innovative approach to uncommon conditions (such as congenital adrenal hyperplasia, transgender conditions). In addition to presenting clinical insights, and a review of the basic science underpinning these conditions, it focuses on key concepts that can be derived from these rare conditions to the entire field. This book is an essential addition to the library for any busy clinician who is looking for a practical reference guide but also for the sub-specialist who is looking for new and thought-provoking insights in this complex scientific area.
Author : Donald W. Pfaff
Publisher : Springer Science & Business Media
Page : 204 pages
File Size : 18,23 MB
Release : 2008-05-31
Category : Medical
ISBN : 3540792880
This book concentrates on two major topics: firstly, the molecular and neural biology of hormone actions relevant to normal social behaviors; and secondly, the clinical treatment of human patients in whom these behaviors have gone wrong.
Author : National Research Council
Publisher : National Academies Press
Page : 453 pages
File Size : 41,58 MB
Release : 2000-02-03
Category : Science
ISBN : 0309064198
Some investigators have hypothesized that estrogens and other hormonally active agents found in the environment might be involved in breast cancer increases and sperm count declines in humans as well as deformities and reproductive problems seen in wildlife. This book looks in detail at the science behind the ominous prospect of "estrogen mimics" threatening health and well-being, from the level of ecosystems and populations to individual people and animals. The committee identifies research needs and offers specific recommendations to decision-makers. This authoritative volume: Critically evaluates the literature on hormonally active agents in the environment and identifies known and suspected toxicologic mechanisms and effects of fish, wildlife, and humans. Examines whether and how exposure to hormonally active agents occursâ€"in diet, in pharmaceuticals, from industrial releases into the environmentâ€"and why the debate centers on estrogens. Identifies significant uncertainties, limitations of knowledge, and weaknesses in the scientific literature. The book presents a wealth of information and investigates a wide range of examples across the spectrum of life that might be related to these agents.
Author : R. Pasquali
Publisher : Karger Medical and Scientific Publishers
Page : 201 pages
File Size : 41,3 MB
Release : 2019-09-09
Category : Medical
ISBN : 3318064718
Hyperandrogenism profoundly affects women’s lives from lowering self-esteem to changing cognition and affective motivation. The polycystic ovary syndrome (PCOS) is the most common androgen excess disorder worldwide. While it is not the focus of this book, some aspects are discussed. The aim of this book is to improve understanding of androgen excess and its impact on several conditions. Topics include development of adipose tissue in females, insulin sensitivity, congenital adrenal hyperplasia, and Cushing’s disease/syndrome. There is also a discussion of PCOS with emphasis on in utero origins and specific genetic and epigenetic factors. This book provides a wealth of relevant information for every endocrinologist and gynecologist who wants to broaden their knowledge of androgens in various conditions.
Author : A. Hughes
Publisher : Springer Science & Business Media
Page : 635 pages
File Size : 32,11 MB
Release : 2013-11-27
Category : Medical
ISBN : 364280859X