Ankylosing spondylitis and Klebsiella


Book Description

Ankylosing spondylitis and Klebsiella is a comprehensive and informative text on the cause of Ankylosing spondylitis. Ankylosing spondylitis (AS) is a condition which affects 20 million people worldwide and is likely caused or initiated by a bowel infection from Klebsiella bacteria. When a patient is infected by Klebsiella bacteria, his or her immune system will make antibodies against all the antigens or molecules found in the microbe. Because some of the bacterial antigens resemble self tissues, the anti-bacterial antibodies will attack not only the bacteria but also the self tissues such as the joints and the cells having the same HLA molecules, which is how the disease AS starts. This is the concept of molecular similarity or “molecular mimicry” which previously has been found to work in two other autoimmune diseases; rheumatic fever and rheumatoid arthritis. The first paper on this subject was published in 1976 and since then over 100 papers on rheumatological topics have been published, from Prof Ebringer’s group, at the Division of Life Sciences, King’s College in London, UK. The relevant information from these papers is extracted and presented in this book format making it accessible to health professionals, research institutions, pharmaceutical companies and universities and the general public.




The IBS Low-Starch Diet


Book Description

Twenty per cent of the UK population - 12 million people - suffer IBS-related symptoms, but they may be unaware that the simple elimination of starch from their diet can bring dramatic relief from pain and discomfort. In this revised edition, Carol Sinclair, a sufferer who has successfully overcome IBS and arthritic pain, brings you a revolutionary programme for a pain-free future. This practical guide will help millions to reduce their arthritic symptoms, whose pain to date has been relieved only by regular medication, with sometimes dangerous side effects. The diet shows that a gradual reduction of starch in one's diet can dramatically reduce pain in days, to a point where drug usage is reduced and, in some cases, eliminated completely. Details of the discovery - along with case histories and a practical guide - make Carol Sinclair's book a first in the world. The IBS Low-Starch Diet also contains over 200 delicious starch- and gluten-free recipes, along with a comprehensive guide to eating out.




Fix Your Gut


Book Description

Keys to unlock the gateway to health, starting with your digestion.Years of research on the most cutting-edge gut interventions like probiotics, prebiotics, and herbal/mineral supplementation, combined with data and observation from regular consultation on digestive ailments, have culminated in this 3rd Edition of the definitive guide to your gut health, Fix Your Gut. Find out the real causes of surface-level digestive disturbances like acid reflux, heartburn, excessive burping/indigestion, and even the occasional gas. Benefit from the holistic results of your new and improved digestion.There is an average of 70 million Americans diagnosed with digestive disorders every year. More and more Americans are rushing to their doctors to treat conditions like heartburn, gas, GERD, SIBO, IBS, ulcerative colitis, and Crohn's disease. In our modern world, more digestive diseases and problems are being discovered than ever before.The most concerning aspect in light of this onslaught of illnesses is that science and natural medicine are already way ahead of the curve in relieving them, yet patients are not being given answers. When digestion tanks, most people turn to conventional medicine, which is great for emergency procedures and life-threatening conditions, but often doesn't offer what is needed for the prevention and treatment of disease.In everyone's medical treatment, there are benefits from a balance of natural and conventional medicine. Individuals deserve to be given the information required to make their own decisions, not only in treatment options for problems that might arise, but in the development of a healthy overall lifestyle.This book gives you the best interventions to improve your gut health, including how to change your diet to optimize your digestive system and enhance total body function. An ideal digestive system eliminates toxins, governs the immune system, absorbs nutrients, provides peek mental health, and ultimately makes it possible to get the most out of life.This is the only guide that examines all available treatments for hacking and maximizing your microbiome, down to each species of probiotic bacteria and every molecule of prebiotic fiber that might be utilized. Probiotics, prebiotics, herbal remedies, diet and lifestyle changes, and even pharmaceutical drugs are held under the microscope to help determine a gut-healing protocol that's right for your specific goals.We are all individuals with different genetics, microbiomes, and allergies, so every contingency is accounted for in the diverging paths of healing provided within this guide.In his definitive work, John Brisson explores and explains everything you need to know about digestive health. Fix Your Gut covers (and helps you discover):-How Your Digestive System Really Works-Tips to Improve Digestive Health-Probiotic Guide and Information (All Different Flora and Their Uses)-Supplement Brand Recommendations (Quality Matters)-Buying Supplements Online and Locally-Protocols for Most Digestive Diseases (GERD, LERD, SIBO, Gastritis, Gastroparesis, IBS, IBD, Esophageal Motility Disorders)-Protocols for Colon Cleansing and Parasite Elimination-Protocols for Constipation, Diarrhea, and Food Poisoning-Protocols to treat Candida, H. pylori, and C. diff Infections-The True Cause of Ulcerative Colitis and Crohn's Disease-Information on Different Diets and How They Affect Your Digestive Health-Gastrointestinal Cancer General Information and Alternative Treatments-Information on Antibiotics and Medicines Used to Treat Digestive Diseases-Information on Digestive Diagnostic ProceduresIt's time to take back your digestive health!www.fixyourgut.com




Atlas of Uveitis


Book Description

This Atlas provides cutting-edge information on uveitis, which represents a major achievement in clinical studies on uveitis. It includes more than three thousand imaging photos of uveitis patients, showing the disease’s complete profile and the spectrum of variations commonly encountered. Numerous therapeutic regimens are also presented, each of which is designed for a specific form of uveitis. The Atlas also incorporates the latest advances in uveitis studies, making it a unique and valuable resource for a broad readership, including ophthalmologists, postgraduate students, medical students and doctors in ophthalmology.




Superbugs


Book Description

The first section of this book discusses Clostridium difficile Infections (CDI). There is no consensus on the definition of severe CDI, since it varies depending on the authors or clinical practice guidelines consulted. Severe CDI can be defined as an episode of CDI with one or more specific signs and symptoms of severe colitis or a complicated clinical course, with significant systemic toxicity and shock, requiring ICU admission or a colectomy, or resulting in death. The chapters in this section examine the risk factors for the development of severe CDI; study the advances in fecal microbiota transplantation; and provide management strategies of CDI in intensive care units. Section Two of this book provides research on Klebsiella pneumoniae infections. Klebsiella pneumoniae producing KPC-type carbapenemase (KPC-Kp) is an emerging problem epidemiologically, diagnostically, and therapeutically. Carbapenem-resistant Klebsiella pneumoniae have emerged as a class of pathogens that pose a significant threat to patients admitted to healthcare facilities. The first chapter of this section reviews the molecular epidemiology of Klebsiella pneumoniae carbapenemase. The following chapters discuss KPC-Kp; Klebsiella pneumoniae brain abscess in adults; and the causes of Ankylosing spondylitis and Crohn's disease.




Ankylosing Spondylitis - Axial Spondyloarthritis


Book Description

Ankylosing Spondylitis is a chronic autoimmune disease that affects about 1-3% of the world population. This debilitating disease affecting primarily young males exerts considerable socio-economic consequences. The exact pathogenesis of AS has not yet been fully understood; therefore, novel, detailed information sources are required. This book offers cutting-edge knowledge about the molecular basic and immunological mechanisms involved in the pathogenesis of Ankylosing Spondylitis. It is one of the scarce scientific resources discussing the environmental factors triggering the disease, along with the clinical manifestations, diagnostic methods, and treatments. This book covers the most recent and reliable researches and developments about spondyloarthropathies in order to provide elaborated, integrated guidance on the molecular mechanisms of Spondyloarthropathies. It will prove helpful for rheumatologists, immunologists, biologists, geneticists, and medical science students who wish to learn more about SpAs.




The Human Microbiota and Chronic Disease


Book Description

Microbiota-associated pathology can be a direct result of changes in general bacterial composition, such as might be found in periodontitis and bacterial vaginosis, and/or as the result of colonization and/or overgrowth of so called keystone species. The disruption in the composition of the normal human microbiota, or dysbiosis, plays an integral role in human health and human disease. The Human Microbiota and Human Chronic Disease: Dysbioses as a Cause of Human Pathology discusses the role of the microbiota in maintaining human health. The text introduces the reader to the biology of microbial dysbiosis and its potential role in both bacterial disease and in idiopathic chronic disease states. Divided into five sections, the text delineates the concept of the human bacterial microbiota with particular attention being paid to the microbiotae of the gut, oral cavity and skin. A key methodology for exploring the microbiota, metagenomics, is also described. The book then shows the reader the cellular, molecular and genetic complexities of the bacterial microbiota, its myriad connections with the host and how these can maintain tissue homeostasis. Chapters then consider the role of dysbioses in human disease states, dealing with two of the commonest bacterial diseases of humanity – periodontitis and bacterial vaginosis. The composition of some, if not all microbiotas can be controlled by the diet and this is also dealt with in this section. The discussion moves on to the major ‘idiopathic’ diseases afflicting humans, and the potential role that dysbiosis could play in their induction and chronicity. The book then concludes with the therapeutic potential of manipulating the microbiota, introducing the concepts of probiotics, prebiotics and the administration of healthy human faeces (faecal microbiota transplantation), and then hypothesizes as to the future of medical treatment viewed from a microbiota-centric position. Provides an introduction to dysbiosis, or a disruption in the composition of the normal human microbiota Explains how microbiota-associated pathology and other chronic diseases can result from changes in general bacterial composition Explores the relationship humans have with their microbiota, and its significance in human health and disease Covers host genetic variants and their role in the composition of human microbial biofilms, integral to the relationship between human health and human disease Authored and edited by leaders in the field, The Human Microbiota and Human Chronic Disease will be an invaluable resource for clinicians, pathologists, immunologists, cell and molecular biologists, biochemists, and system biologists studying cellular and molecular bases of human diseases.







The Keystone Approach


Book Description

Healing Arthritis and Psoriasis by Restoring the Microbiome




Ankylosing Spondylitis


Book Description

Ankylosing Spondylitis (AS) and related diseases called spondyloarthropathies (SpA) are the second most common form of chronic inflammatory arthritis after Rheumatoid Arthritis (RA). Unfortunately, most patients with AS and SpA are either never diagnosed, or they are inadequately treated. The current mean delay in the diagnosis of AS ranges from 5 to 10 years, and the presenting clinical manifestations of these diseases are wide-ranging and heterogeneous, and thus a variety of health care professionals see AS and SpA patients, from primary care physicians to rheumatologists and other medical and surgical specialists. With the availability of newer, highly effective treatments and better methods of musculoskeletal imaging, such as the MRI, there is an urgent need to improve early diagnosis and reduce any inappropriate delay in obtaining effective treatment. Earlier diagnosis and treatment can mitigate the severity of the disease, and make a meaningful difference for patient care and quality of life. The proposed book is designed for specialists and generalists alike, and is intenteded to expedite accurate diagnosis and initiation of appropriate treatment in order to alleviate unnecessary suffering. Part of the new Oxford American Rheumatology Library series, this pocket-sized book provides practical, evidence-based information for clinicians to aid diagnosis, treatment, and follow-up care for patients with AS and SpA. The book provides pointers to early diagnosis, prognosis, clinical manifestations, socioeconomic aspects, and disease management. It also provides comprehensive coverage of current treatment options, including the latest biologics, as well as non-drug therapies.