Applications and Methods in Genomic Networks
Author : Kimberly Glass
Publisher : Frontiers Media SA
Page : 234 pages
File Size : 49,26 MB
Release : 2022-07-01
Category : Science
ISBN : 2889764826
Author : Kimberly Glass
Publisher : Frontiers Media SA
Page : 234 pages
File Size : 49,26 MB
Release : 2022-07-01
Category : Science
ISBN : 2889764826
Author : Steve Horvath
Publisher : Springer Science & Business Media
Page : 433 pages
File Size : 22,17 MB
Release : 2011-04-30
Category : Science
ISBN : 144198819X
High-throughput measurements of gene expression and genetic marker data facilitate systems biologic and systems genetic data analysis strategies. Gene co-expression networks have been used to study a variety of biological systems, bridging the gap from individual genes to biologically or clinically important emergent phenotypes.
Author : Institute of Medicine
Publisher : National Academies Press
Page : 354 pages
File Size : 37,50 MB
Release : 2012-09-13
Category : Science
ISBN : 0309224187
Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.
Author : Fabricio Alves Barbosa da Silva
Publisher : Springer Nature
Page : 381 pages
File Size : 37,9 MB
Release : 2020-10-03
Category : Computers
ISBN : 3030518620
This book presents a range of current research topics in biological network modeling, as well as its application in studies on human hosts, pathogens, and diseases. Systems biology is a rapidly expanding field that involves the study of biological systems through the mathematical modeling and analysis of large volumes of biological data. Gathering contributions from renowned experts in the field, some of the topics discussed in depth here include networks in systems biology, the computational modeling of multidrug-resistant bacteria, and systems biology of cancer. Given its scope, the book is intended for researchers, advanced students, and practitioners of systems biology. The chapters are research-oriented, and present some of the latest findings on their respective topics.
Author : Sukanta Mondal
Publisher : Academic Press
Page : 340 pages
File Size : 18,24 MB
Release : 2020-11-25
Category : Science
ISBN : 0128206128
Advances in Animal Genomics provides an outstanding collection of integrated strategies involving traditional and modern - omics (structural, functional, comparative and epigenomics) approaches and genomics-assisted breeding methods which animal biotechnologists can utilize to dissect and decode the molecular and gene regulatory networks involved in the complex quantitative yield and stress tolerance traits in livestock. Written by international experts on animal genomics, this book explores the recent advances in high-throughput, next-generation whole genome and transcriptome sequencing, array-based genotyping, and modern bioinformatics approaches which have enabled to produce huge genomic and transcriptomic resources globally on a genome-wide scale. This book is an important resource for researchers, students, educators and professionals in agriculture, veterinary and biotechnology sciences that enables them to solve problems regarding sustainable development with the help of current innovative biotechnologies. - Integrates basic and advanced concepts of animal biotechnology and presents future developments - Describes current high-throughput next-generation whole genome and transcriptome sequencing, array-based genotyping, and modern bioinformatics approaches for sustainable livestock production - Illustrates integrated strategies to dissect and decode the molecular and gene regulatory networks involved in complex quantitative yield and stress tolerance traits in livestock - Ensures readers will gain a strong grasp of biotechnology for sustainable livestock production with its well-illustrated discussion
Author : Sándor Suhai
Publisher : Springer Science & Business Media
Page : 248 pages
File Size : 40,10 MB
Release : 1994
Category : Medical
ISBN : 9780306447129
Chapters originating as plenary lectures at the July 1992 symposium provide a bridge between experimental databases (information) on the one hand and theoretical concepts (biological and genetic knowledge) on the other. Among the topics: informatics and experiments for the Human Genome Project; the
Author : Daskalaki, Andriani
Publisher : IGI Global
Page : 982 pages
File Size : 20,68 MB
Release : 2008-11-30
Category : Technology & Engineering
ISBN : 1605660779
"This book highlights the use of systems approaches including genomic, cellular, proteomic, metabolomic, bioinformatics, molecular, and biochemical, to address fundamental questions in complex diseases like cancer diabetes but also in ageing"--Provided by publisher.
Author : Guido Sanguinetti
Publisher : Humana
Page : 0 pages
File Size : 22,69 MB
Release : 2018-12-14
Category : Science
ISBN : 9781493988815
This volume explores recent techniques for the computational inference of gene regulatory networks (GRNs). The chapters in this book cover topics such as methods to infer GRNs from time-varying data; the extraction of causal information from biological data; GRN inference from multiple heterogeneous data sets; non-parametric and hybrid statistical methods; the joint inference of differential networks; and mechanistic models of gene regulation dynamics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, descriptions of recently developed methods for GRN inference, applications of these methods on real and/ or simulated biological data, and step-by-step tutorials on the usage of associated software tools. Cutting-edge and thorough, Gene Regulatory Networks: Methods and Protocols is an essential tool for evaluating the current research needed to further address the common challenges faced by specialists in this field.
Author : Mark Buchanan
Publisher : Cambridge University Press
Page : 282 pages
File Size : 22,31 MB
Release : 2010-05-13
Category : Science
ISBN : 0521882737
Key introductory text for graduate students and researchers in physics, biology and biochemistry.
Author : Alpan Raval
Publisher : CRC Press
Page : 329 pages
File Size : 38,80 MB
Release : 2016-04-19
Category : Computers
ISBN : 1420010360
The new research area of genomics-inspired network biology lacks an introductory book that enables both physical/computational scientists and biologists to obtain a general yet sufficiently rigorous perspective of current thinking. Filling this gap, Introduction to Biological Networks provides a thorough introduction to genomics-inspired network bi