Molecular Epidemiology


Book Description

This book will serve as a primer for both laboratory and field scientists who are shaping the emerging field of molecular epidemiology. Molecular epidemiology utilizes the same paradigm as traditional epidemiology but uses biological markers to identify exposure, disease or susceptibility. Schulte and Perera present the epidemiologic methods pertinent to biological markers. The book is also designed to enumerate the considerations necessary for valid field research and provide a resource on the salient and subtle features of biological indicators.




Extractive Metallurgy of Niobium


Book Description

The growth and development witnessed today in modern science, engineering, and technology owes a heavy debt to the rare, refractory, and reactive metals group, of which niobium is a member. Extractive Metallurgy of Niobium presents a vivid account of the metal through its comprehensive discussions of properties and applications, resources and resource processing, chemical processing and compound preparation, metal extraction, and refining and consolidation. Typical flow sheets adopted in some leading niobium-producing countries for the beneficiation of various niobium sources are presented, and various chemical processes for producing pure forms of niobium intermediates such as chloride, fluoride, and oxide are discussed. The book also explains how to liberate the metal from its intermediates and describes the physico-chemical principles involved. It is an excellent reference for chemical metallurgists, hydrometallurgists, extraction and process metallurgists, and minerals processors. It is also valuable to a wide variety of scientists, engineers, technologists, and students interested in the topic.




Gray's Clinical Photographic Dissector of the Human Body E-Book


Book Description

Perfect for hands-on reference, Gray's Clinical Photographic Dissector of the Human Body, 2nd Edition is a practical resource in the anatomy lab, on surgical rotations, during clerkship and residency, and beyond! The fully revised second edition of this unique dissection guide uses superb full-color photographs to orient you more quickly in the anatomy lab, and points out the clinical relevance of each structure and every dissection. - Perform dissections with confidence by comparing the 1,098 full-color photographs to the cadavers you study. - Easily relate anatomical structures to clinical conditions and procedures. - Understand the pertinent anatomy for more than 30 common clinical procedures such as lumbar puncture and knee aspiration, including where to make the relevant incisions. - Depend on the same level of accuracy and thoroughness that have made Gray's Anatomy the defining reference on this complex subject, thanks to the expertise of the author team - all leading authorities in the world of clinical anatomy. - New and improved photographs guide you through each dissection step-by-step. - All-new page design, incorporating explanatory diagrams alongside photographs to more easily orientate you on the cadaver. - Corresponding Gray's illustrations added to aid understanding and add clarity to key anatomical structures. - New coverage of the pelvis and perineum added to this edition. - Evolve Instructor Resources, including a downloadable image and test bank, are available to instructors through their Elsevier sales rep or via request at: https://evolve.elsevier.com




Braunwald's Heart Disease Review and Assessment E-Book


Book Description

With more than 700 review questions derived from and keyed to the newly revised 11th Edition of Braunwald's Heart Disease, Braunwald’s Heart Disease Review and Assessment, 11th Edition, is the perfect review tool for fellows, residents, and practitioners to prepare for board exams in cardiovascular medicine. Noted Harvard educator Dr. Leonard S. Lilly, with assistance from faculty and fellows at Brigham & Women’s Hospital, provides a thorough, clear, and concise overview of the entire field, helping ensure your mastery of all key aspects of today’s cardiology. This title is a one-stop resource for complete, authoritative coverage of the most important concepts in cardiovascular medicine – ideal for self-assessment, individualized study, and clinical practice. Uses a completely reorganized format throughout, matching the reorganization of Braunwald’s Heart Disease, 11th Edition. Provides new coverage of biomarkers and their use in precision medicine, cardio-oncology, sleep disordered breathing and CVD, the latest hypertension guidelines, reversal agents for the novel oral anticoagulants, and diabetes medications with recently proven cardiovascular benefits. Covers current topics such as cardiovascular genetics, innovative heart failure medications and devices, non-culprit percutaneous coronary intervention, selection of antithrombotic drugs, transcatheter valve procedures, and use of left atrial appendage exclusion procedures in atrial fibrillation. Features detailed answers that comprise "mini-reviews" of the material, and cross references to the main text that make it easy to find definitive explanations for any question. Contains full-color images and illustrations throughout, and numerous case studies that enhance your study and improve retention of complex material.




The Wondrous Story of Anesthesia


Book Description

Edited and written by an international "who's who" of more than 100 authors, including anesthesiologists, nurse anesthetists, bench scientists, a surgeon, and representatives of industry, this text provides a comprehensive history of anesthesia, unique in its focus on the people and events that shaped the specialty around the world, particularly during the past 70 years when anesthesia emerged from empiricism and developed into a science-based practice.




Flow Cytometry


Book Description

Flow cytometry continually amazes scientists with its ever-expanding utility. Advances in flow cytometry have opened new directions in theoretical science, clinical diagnosis, and medical practice. The new edition of Flow Cytometry: First Principles provides a thorough update of this now classic text, reflecting innovations in the field while outlining the fundamental elements of instrumentation, sample preparation, and data analysis. Flow Cytometry: First Principles, Second Edition explains the basic principles of flow cytometry, surveying its primary scientific and clinical applications and highlighting state-of-the-art techniques at the frontiers of research. This edition contains extensive revisions of all chapters, including new discussions on fluorochrome and laser options for multicolor analysis, an additionalsection on apoptosis in the chapter on DNA, and new chapters onintracellular protein staining and cell sorting, including high-speed sorting and alternative sorting methods, as well as traditional technology. This essential resource: Assumes no prior knowledge of flow cytometry Progresses with an informal, engaging lecture style from simpleto more complex concepts Offers a clear introduction to new vocabulary, principles of instrumentation, and strategies for data analysis Emphasizes the theory relevant to all flow cytometry, with examples from a variety of clinical and scientific fields Flow Cytometry: First Principles, Second Edition provides scientists, clinicians, technologists, and students with the knowledge necessary for beginning the practice of flow cytometry and for understanding related literature.




The 71F Advantage


Book Description

Includes a foreword by Major General David A. Rubenstein. From the editor: "71F, or "71 Foxtrot," is the AOC (area of concentration) code assigned by the U.S. Army to the specialty of Research Psychology. Qualifying as an Army research psychologist requires, first of all, a Ph.D. from a research (not clinical) intensive graduate psychology program. Due to their advanced education, research psychologists receive a direct commission as Army officers in the Medical Service Corps at the rank of captain. In terms of numbers, the 71F AOC is a small one, with only 25 to 30 officers serving in any given year. However, the 71F impact is much bigger than this small cadre suggests. Army research psychologists apply their extensive training and expertise in the science of psychology and social behavior toward understanding, preserving, and enhancing the health, well being, morale, and performance of Soldiers and military families. As is clear throughout the pages of this book, they do this in many ways and in many areas, but always with a scientific approach. This is the 71F advantage: applying the science of psychology to understand the human dimension, and developing programs, policies, and products to benefit the person in military operations. This book grew out of the April 2008 biennial conference of U.S. Army Research Psychologists, held in Bethesda, Maryland. This meeting was to be my last as Consultant to the Surgeon General for Research Psychology, and I thought it would be a good idea to publish proceedings, which had not been done before. As Consultant, I'd often wished for such a document to help explain to people what it is that Army Research Psychologists "do for a living." In addition to our core group of 71Fs, at the Bethesda 2008 meeting we had several brand-new members, and a number of distinguished retirees, the "grey-beards" of the 71F clan. Together with longtime 71F colleagues Ross Pastel and Mark Vaitkus, I also saw an unusual opportunity to capture some of the history of the Army Research Psychology specialty while providing a representative sample of current 71F research and activities. It seemed to us especially important to do this at a time when the operational demands on the Army and the total force were reaching unprecedented levels, with no sign of easing, and with the Army in turn relying more heavily on research psychology to inform its programs for protecting the health, well being, and performance of Soldiers and their families."




Public Health Implications of Raising the Minimum Age of Legal Access to Tobacco Products


Book Description

Tobacco use by adolescents and young adults poses serious concerns. Nearly all adults who have ever smoked daily first tried a cigarette before 26 years of age. Current cigarette use among adults is highest among persons aged 21 to 25 years. The parts of the brain most responsible for cognitive and psychosocial maturity continue to develop and change through young adulthood, and adolescent brains are uniquely vulnerable to the effects of nicotine. At the request of the U.S. Food and Drug Administration, Public Health Implications of Raising the Minimum Age of Legal Access to Tobacco Products considers the likely public health impact of raising the minimum age for purchasing tobacco products. The report reviews the existing literature on tobacco use patterns, developmental biology and psychology, health effects of tobacco use, and the current landscape regarding youth access laws, including minimum age laws and their enforcement. Based on this literature, the report makes conclusions about the likely effect of raising the minimum age to 19, 21, and 25 years on tobacco use initiation. The report also quantifies the accompanying public health outcomes based on findings from two tobacco use simulation models. According to the report, raising the minimum age of legal access to tobacco products, particularly to ages 21 and 25, will lead to substantial reductions in tobacco use, improve the health of Americans across the lifespan, and save lives. Public Health Implications of Raising the Minimum Age of Legal Access to Tobacco Products will be a valuable reference for federal policy makers and state and local health departments and legislators.




Laboratory Techniques in Thrombosis - A Manual


Book Description

The first edition of this manual appeared in 1992 and was entitled ECAT Assay Procedures. This completely revised new edition combines the strengths of the first edition with new and useful features. Laboratory Techniques in Thrombosis - a Manual still gives detailed descriptions of the recommended assays and their alternatives. However, the manual now has a broader scope because it is no longer limited by the frontiers of ECAT. Experts all over the world have contributed to this edition. Furthermore, new assays have been introduced, improvements have been suggested for other assays, while a few others have become redundant or no longer available. The list of manufacturers is fully updated and a list of the recommended nomenclature of quantities in thrombosis and haemostasis is new to this edition, further facilitating the use of this manual. Laboratory Techniques in Thrombosis - a Manual will contribute to furthering the much needed harmonization and standardization of tests within the field and should have a place in all working haemostasis laboratories.