Beriberi in Modern Japan


Book Description

The history of the medical and scientific debate about the etiology of the disease as it played out between diet theorists and contagionists from 1880 to 1940. In modern Japan, beriberi (or thiamin deficiency) became a public health problem that cut across all social boundaries, afflicting even the Meiji Emperor. During an age of empire building for the Japanese nation, incidence rates in the military ranged from 30 percent in peacetime to 90 percent during war. Doctors and public health officials called beriberi a "national disease" because it festered within the bodies of the people and threatened the health ofthe empire. Nevertheless, they could not agree over what caused the disease, attributing it to a diet deficiency or a microbe. In Beriberi in Modern Japan, Alexander R. Bay examines the debates over the etiologyof this "national disease" during the late nineteenth and early twentieth centuries. Etiological consensus came after World War I, but the struggle at the national level to direct beriberi prevention continued, peaking during wartime mobilization. War served as the context within which scientific knowledge of beriberi and its prevention was made. The story of beriberi research is not simply about the march toward the inevitable discovery of "the beriberi vitamin," but rather the history of the role of medicine in state-making and empire-building in modern Japan. Alexander Bay is assistant professor of history at Chapman University.




Beriberi, White Rice, and Vitamin B


Book Description

In this comprehensive account of the history and treatment of beriberi, Kenneth Carpenter traces the decades of medical and chemical research that solved the puzzle posed by this mysterious disease. Caused by the lack of a minute quantity of the chemical thiamin, or vitamin B1 in the diet, beriberi is characterized by weakness and loss of feeling in the feet and legs, then swelling from fluid retention, and finally heart failure. Western doctors working in Asia after 1870 saw it as the major disease in native armed forces and prisons. It was at first attributed to miasms (poisonous vapors from damp soil) or to bacterial infections. In Java, chickens fed by chance on white rice lost the use of their legs. On brown rice, where the grain still contained its bran and germ, they remained healthy. Studies in Javanese prisons then showed beriberi also occurring where white (rather than brown) rice was the staple food. Birds were used to assay the potency of fractions extracted from rice bran and, after 20 years, highly active crystals were obtained. In another 10 years their structure was determined and "thiamin" was synthesized. Beriberi is a story of contested knowledge and erratic scientific pathways. It offers a fascinating chronicle of the development of scientific thought, a history that encompasses public health, science, diet, trade, expanding empires, war, and technology. From the preface: This is a medical detective story: beginning with the investigation of a disease that has killed or crippled at least a million people, and then following up clues that ranged much wider. One outcome was the production of a synthetic chemical that we now, nearly all of us, consume in small quantities each day in our food. The detectives had a variety of professions and spoke different languages. Their work ranged from studying the health of laborers in a primitive jungle to the painstaking dissection of individual grains of rice under a microscope. The integrated story of their struggles and successes, culled from old volumes in scattered libraries, forms the subject of this book.




Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc


Book Description

This volume is the newest release in the authoritative series issued by the National Academy of Sciences on dietary reference intakes (DRIs). This series provides recommended intakes, such as Recommended Dietary Allowances (RDAs), for use in planning nutritionally adequate diets for individuals based on age and gender. In addition, a new reference intake, the Tolerable Upper Intake Level (UL), has also been established to assist an individual in knowing how much is "too much" of a nutrient. Based on the Institute of Medicine's review of the scientific literature regarding dietary micronutrients, recommendations have been formulated regarding vitamins A and K, iron, iodine, chromium, copper, manganese, molybdenum, zinc, and other potentially beneficial trace elements such as boron to determine the roles, if any, they play in health. The book also: Reviews selected components of food that may influence the bioavailability of these compounds. Develops estimates of dietary intake of these compounds that are compatible with good nutrition throughout the life span and that may decrease risk of chronic disease where data indicate they play a role. Determines Tolerable Upper Intake levels for each nutrient reviewed where adequate scientific data are available in specific population subgroups. Identifies research needed to improve knowledge of the role of these micronutrients in human health. This book will be important to professionals in nutrition research and education.







Thiamine Deficiency and Associated Clinical Disorders


Book Description

Thiamine deficiency and related clinical disorders represent an intriguing area of both basic and clinical investigation. Modern imaging strategies have facilitated the rapid treatment, and potential reversal of these clinical disorders. The fusion of laboratory and clinical knowledge serve as an example of how research can translate to successful treatment. The goal of Thiamine Deficiency and Related Clinical Disorders is to bring together cogent results from basic and clinical investigation and to stimulate further investigations in these areas. This data will be useful to neurologists, internists, nutritionists, biochemists, neurochemists, neuroscientists, and others with interest in thiamine deficiency.




Beriberi, WhiteRice, and Vitamin B


Book Description

Traces the decades of medical & chemical research that solved the puzzle posed by beriberi, a mysterious disease that is caused by the lack of a minute quantity of the chemical thiamin, or vitamin B1, in the diet. Western doctors working in Asia after 1870 saw it as the major disease among those who ate white rice, while people eating brown rice, where the grain still contained its bran & germ, remained healthy. Research finally enabled the synthesis of thiaminÓ, which is now used to enrich white rice & flour in most advanced countries, but not in poorer countries where the disease has been endemic. A fascinating chronicle of a history that encompasses public health, science, diet, trade, expanding empires, war, & technology.Ó Illustrated.




Beriberi, White Rice, and Vitamin B


Book Description

This book travels through a century of of puzzlement that took place betweenPerry's landing and the use of Vitamin B in the late 1930s. The result is a case study of how an obscure disease rises to international prominance and challenges the experts in public health and nutrition.




Agents of Apocalypse


Book Description

As waves of epidemic disease swept the Philippines in the late nineteenth century, some colonial physicians began to fear that the indigenous population would be wiped out. Many Filipinos interpreted the contagions as a harbinger of the Biblical Apocalypse. Though the direct forebodings went unfulfilled, Philippine morbidity and mortality rates were the world's highest during the period 1883-1903. In Agents of Apocalypse, Ken De Bevoise shows that those "mourning years" resulted from a conjunction of demographic, economic, technological, cultural, and political processes that had been building for centuries. The story is one of unintended consequences, fraught with tragic irony. De Bevoise uses the Philippine case study to explore the extent to which humans participate in creating their epidemics. Interpreting the archival record with conceptual guidance from the health sciences, he sets tropical disease in a historical framework that views people as interacting with, rather than acting within, their total environment. The complexity of cause-effect and agency-structure relationships is thereby highlighted. Readers from fields as diverse as Spanish, American, and Philippine history, medical anthropology, colonialism, international relations, Asian studies, and ecology will benefit from De Bevoise's insights into the interdynamics of historical processes that connect humans and their diseases.




Vitamin History, the Early Years


Book Description

The term ""vitamine"" was first used 101 years ago in 1912. What were later to be known as vitamin-deficiency diseases, such as scurvy, beriberi, night blindness, xeropthalmia, pellagra, pernicious anemia and rickets, had plagued the world since the existence of written records. The book contains 10 chapters and traces each vitamin from an unidentified factor to its discovery and synthesis.




Beriberi


Book Description