Biochemical Actions of Hormones V9


Book Description

Biochemical Actions of Hormones, Volume IX is an 11-chapter text that provides the developments in the theoretical and experimental understanding of hormonal actions and regulation. After presenting an overview of research on peptide and steroid hormones, this volume goes on exploring the lipotropins and their active degradation products, as well as the adenylate cyclase enzyme regulation by adrenergic receptors. These topics are followed by discussions on the potassium ion conductance in the pancreatic beta cell; the concept of the insulin sensitive chemoreceptor of the central nervous system; the estrogen-induced growth factors and their role in tumor cell growth; and the nuclear acceptors for the avian progesterone receptor. Other chapters consider the structural aspects of steroid hormones and their receptors, with an emphasis on the importance of pyridoxal phosphate research studies on a better understanding of the steroid receptors function. This book also looks into an affinity label for glucocorticoid receptors and the development of a polyclonal antibody for this receptor. The concluding chapter emphasizes the regulation of the steroid sulfotransferases. This volume will be of great value to biologists, biochemists, and researchers who are interested in the biochemical aspects of hormones.




Biochemical Actions of Hormones V3


Book Description

Biochemical Actions of Hormones, Volume III is a collection of papers that deals with steroid hormone action, hypothalamic-regulating hormones, plasma membrane receptors, thyroid hormones, hormones acting on the synthesis of proteins in liver perfusion systems, as well as on approaches using genetics and cell culture. One paper explains why cell hybridization can be a useful technique in studying both genetic control of differentiated functions and of hormonal induction. Another paper discusses the general approaches in the study of ligand-membrane interactions, and cites experiments dealing with polypeptide hormones and catecholamines. It explains in detail the physiochemical interaction between a radioactively labeled ligand and the plasma membrane, either as found in an intact cell or in an isolated membrane preparation. One paper discusses the introduction and time course of estrogen-stimulated biosynthetic events in the uterus. It analyzes the relationship of the estrogen-binding protein to the biological responses of the uterus, including the "domino" versus "sustained output" model of estrogen action. One paper explains, by using a chick oviduct, how to investigate the hypothesis that hormones can activate genes to allow transcription of new species of messenger RNA. This collection can prove beneficial to biochemists, molecular biologists, cellular biologists, micro-biologists, developmental biologists, and scientists involved in cell research.




Biochemical Actions of Hormones V8


Book Description

Biochemical Actions of Hormones, Volume VIII is an eight-chapter text that covers the developments in the understanding of the biochemical aspects of hormonal action and regulation. This volume examines first the messenger functions of calcium in hormonal systems. The next chapters deal with the neuronal regulation of blood pressure; the regulation of protein synthesis by phosphorylation; and the hormonal control of hepatic gluconeogenesis. These topics are followed by discussions on the effects of insulin in intracellular functions, the mechanisms of steroidal hormones, and the membrane recognition and effector sites in steroid hormone action. A chapter focuses on the activation of steroid-receptor complexes. The final chapters survey the estradiol and progesterone receptors in the human endometrium. This book will be of great value to biologists, biochemists, and researchers in the field of hormonal action.




Biochemical Actions of Hormones V7


Book Description

Biochemical Actions of Hormones, Volume VII is a nine-chapter text that covers a broad range of subjects representing research efforts on hormone action. This book deals first with the developments on hormones of the thymus and the evidence on the regulation of liver steroid and drug metabolism by the hypothalamus and anterior pituitary. These topics are followed by discussions on the regulation by neurotransmitters in the hypothalamus of LHRH and somatostatin; the hormonal regulation of protein degradation in liver and in isolated cells; and the hormonal regulation of lipid mobilization from adipose tissue. Considerable chapters are devoted to steroid hormone mechanisms and the cell genetics of glucocorticoid responsiveness. The remaining chapters explore the mero-receptor and androgenic regulation in male accessory tissue. These chapters also highlight the molecular biological aspects of thyroid hormone action. This volume is an ideal source for biologists, biochemists, and researchers working in the subject and in related fields.




Biochemical Actions of Hormones V4


Book Description

Biochemical Actions of Hormones, Volume IV explores the significant developments toward understanding the primary effects of hormones in cellular receptors at the molecular level. This volume is composed of nine chapters, and begins with a review of the developments in affinity labeling that relate principally to the determination of the mechanisms of hormone action. The following chapters examine the role of prostaglandins in ovarian function and the methods for measuring protein synthesis and degradation in the heart and skeletal muscle. These topics are followed by discussions on the regulation of cholesterol synthesis by individual hormones; the regulatory mechanisms modulating the responsiveness of pineal gland to ß-adrenergic receptor stimulation; and the unitary mechanism of thyrotropin-releasing hormone action in target cells. The remaining chapters cover the insulin binding and insulin receptors from a variety of tissues and diverse species. These chapters also look into the physiology, molecular action, and biological effects of androgens and cyclic adenosine monophosphate. This book will be of great benefit to endocrinologists.




Biochemical Actions of Hormones V5


Book Description

Biochemical Actions of Hormones, Volume V explores the nature of interaction of multiple hormones in regulating specific phenotypes. This volume is organized into 11 chapters that include discussions on the developments in the understanding of the biochemistry and molecular biology of hormones. The opening chapters deal with the modifications of chromatin structure by hormones, the regulation of exocytosis, ontogeny of estrogen receptors, and the hormonal regulation of cells of the seminiferous tubule. The discussions then shift to the advances on the progesterone receptor, the role of glucocorticoids in the integration of mammary tumor virus genes, and a model system for estrogen action. Other chapters examine the physiology, molecular action, and biological effects of somatomedins, epidermal growth factors and 1,25-dihydroxyvitamin. The remaining chapters focus on multihormone control of mRNA for a specific hepatic protein. This book is of great value to endocrinologists.




Biochemical Actions of Hormones V1


Book Description

Biochemical Actions of Hormones, Volume I explores the significant developments toward understanding the primary effects of hormones in cellular receptors at the molecular level. This book is composed of 12 chapters that survey the molecular and biochemical approaches bearing on the problem of hormone mechanism. The opening chapters discuss the thyroid hormonal responses during metamorphic process in Amphibia; the primary role of hormones in biochemical differentiation; the influence of hormones on protein synthesis and the importance of protein synthesis mechanism; and the biochemical rhythms within the pineal gland and the rhythm in hepatic tyrosine transaminase activity. The subsequent chapters examine the effects of a number of hormones on transport systems in the cell membranes, the protein interaction with steroids, and the influence of insulin on protein and nucleic acid metabolism. The remaining five chapters deal with the physiology, mechanism of action, and biological effects of various hormones, such as mineralocorticoids, parathyroid hormone, calcitonin, thyrotropin, and plant hormones. This book is an invaluable source for endocrinologists.




Biochemical Actions of Hormones V14


Book Description

Biochemical Actions of Hormones, Volume XIV is a compendium of papers dealing with DNA regulatory elements, leukotriene receptors, hormonal regulation of sodium-proton exchange activity, the structure of the mammalian progesterone receptor, stimulus-response, and signaling systems. One paper analyzes the hormonal factors that regulate the kinetic properties of the plasma membrane Na+ -H+ exchanger in epithelia and relates the control mechanisms to specific physiological function. Aqueous two-phase partitioning is a method that can be used in the study of steroid receptor activation and other conversions or interactions of steroid receptors. Using the two-phase partitioning, one can form a model of molecular changes during activation based on changes in the steroid receptor physico-chemical properties associated with the activation in vitro-phase. Another paper investigates the hypothesis that early androgenic modulation of nuclear effector-independent PKs is intimately related to the initial events in androgenic control of gene expression in the prostate. One paper describes the interaction between the estrogen receptor with DNA and the mechanism of transcription regulation by steroid receptors. Another paper reviews the role of GTP-binding proteins in receptor-mediated activation of phospholipase C, the formation and metabolism of novel inositol phosphates, as well as the possible role of protein kinase C in signal modulation. Micro-biologists, biochemists, molecular biologists, cellular biologists, and investigators in the field of cell research will find this collection useful.




Biochemical Actions of Hormones V6


Book Description

Biochemical Actions of Hormones, Volume VI is a 10-chapter text that summarizes the regulation of protein kinases and phosphoprotein phosphatases and the relationship of the endocrines to cancer. This volume describes first the precise structures of steroid hormones and carcinogens. The subsequent chapters cover the hormonal regulation of chemical carcinogenesis; the importance of steroid hormones as growth factors for mammary tumors; the effects of steroid hormones in the central nervous system; and the properties of the purified estrogen receptor. A chapter highlights the biochemical actions of neurohypophysial hormones and neurophysin. Another chapter presents the biochemistry and physiology of cytokinin, a plant hormone. The final chapter exemplifies the multihormonal systems by control of the a2u-globulin produced in the liver. This book will be of great value to endocrinologists.