Biochemistry of Vision


Book Description

Biochemistry of Vision provides information pertinent to vision biochemistry. This book discusses the biochemical information derived primarily from studies on nonocular tissues and describes the biochemical reactions related to the function of the retina and pigmented epithelium. Organized into 16 chapters, this book begins with an overview of the visual system and the structure of the vertebrate eye. The text then proceeds with a discussion of photoreceptor, which has a highly membranous structure. Other chapters cover a brief discussion of several topics, including biomembranes, photochemistry, spectral properties of retinal isomers, and the photochemical properties of the chromophore of rhodopsin. This book discusses as well the properties and intramembrane disposition of rhodopsin. The final chapter deals with the biochemistry of photoreceptor disorders and summarizes the basic knowledge on neurotransmitters and electrophysiology in the retina. This book is intended for ophthalmologists and medical students who are interested in the molecular aspects of photoreceptor diseases.




Biochemistry and Physiology of Visual Pigments


Book Description

This book is a report of a four-day Symposium on the Biochemistry and Physiology of Visual Pigments, which took place immediately after the VIth International Congress on Photobiology, held in Bochum, Federal Republic of Germany, in August 1972. This meeting, which brought together about 50 investigators of various aspects of the visual process, was devoted to the visual cells of both vertebrates and invertebrates. Whereas the International Symposium on the Biochemistry of the Retina, held at Nij megen, The Netherlands, in 1968, had concentrated on vertebrate photoreceptors, this Symposium dealt with invertebrate photoreceptors as well, so that workers in each field could become acquainted with recent progress in the other area. The papers presented at the Symposium were divided into six main topics, to each of which a half-day session was devoted. The six parts of this book, following the intro ductory lecture, essentially correspond to these sessions. In addition to the invited con tributions, the volume contains a number of short communications by other partici pants and two contributions by invited participants, who were unable to attend. The volume closes, as did the Symposium, with a General Discussion, prepared and moderated by S. L. BONTING, in which an attempt was made to integrate various new findings, and to reconcile certain points of disagreement.




The Visual System in Vertebrates


Book Description

The vertebrate eye has been, and continues to be, an object of interest and of inquiry for biologists, physicists, chemists, psychologists, and others. Quite apart from its important role in the development of ophthalmology and related medical disciplines, the vertebrate eye is an exemplar of the ingenuity of living systems in adapting to the diverse and changing environments in which vertebrates have evolved. The wonder is not so much that the visual system, like other body systems, has been able to adapt in this way, but rather that these adaptations have taken such a variety of forms. In a previous volume in this series (VII/I) Eakin expressed admiration for the diversity of invertebrate photoreceptors. A comparable situation exists for the vertebrate eye as a whole and one object of this volume is to present to the reader the nature of this diversity. One result of this diversification of ocular structures and properties is that the experimental biologist has available a number of systems for study that are unique or especially favorable for the investigation of particular questions in visual science or neurobiology. This volume includes some examples of progress made by the use of such specially selected vertebrate systems. It is our hope that this comparative approach will continue to reveal new and useful preparations for the examination of important questions.




Anatomy ;Ocular physiology ;Biochemistry and genetics ;Pathology ;Microbiology ;Immunology ;Growth and senescence ;Optics ;Therapeutics ;Lasers and instrument technology ;Basic biostatistical and epidemiological terms


Book Description

An indispensable and fully comprehensive textbook, this covers the basic sciences in ophthalmology and is the only book you need to pass the FRCOphth Part 1 exam.




Photoreceptor Cell Biology and Inherited Retinal Degenerations


Book Description

This important book presents review articles on the cell biology of photoreceptor and RPE cells, as well as the relationship between this cell biology and inherited photoreceptor degeneration. The chapters have been written by leaders in the field. The vision scientist will see this book as a review of photoreceptor and RPE cell biology, and known molecular bases of many forms of retinitis pigmentosa and related retinal degeneration.




Webvision


Book Description




Adaptive Mechanisms in the Ecology of Vision


Book Description

John Lythgoe was one of the pioneers of the 'Ecology of Vision', a subject that he ably delineated in his classic and inspirational book published some 20 years ago [1]. At heart, the original book aimed generally to identify inter-relationships between vision, animal behaviour and the environment. John Lythgoe excelled at identifying the interesting 'questions' in the ecology of an animal that fitted the 'answers' presented by an analysis of the visual system. Over the last twenty years, however, since Lythgoe's landmark publication, much progress has been made and the field has broadened considerably. In particular, our understanding of the 'adaptive mechanisms' underlying the ecology of vision has reached considerable depths, extending to the molecular dimension, partly as a result of development and application of new techniques. This complements the advances made in parallel in clinically oriented vision research [2]. The current book endeavours to review the progress made in the ecology of vision field by bringing together many of the major researchers presently active in the expanded subject area. The contents deal with theoretical and physical considerations of light and photoreception, present examples of visual system structure and function, and delve into aspects of visual behaviour and communi cation. Throughout the book, we have tried to emphasise one of the major themes to emerge within the ecology of vision: the high degree of adaptability that visual mechanisms are capable of undergoing in response to diverse, and dynamic, environments and behaviours.







The Pigmentary System


Book Description

The most comprehensive and integrated book on pigmentation The Pigmentary System, Second Edition, gathers into one convenient, all-inclusive volume a wealth of information about the science of pigmentation and all the common and rare clinical disorders that affect skin color. The two parts, physiology (science) and pathophysiology (clinical disorders), are complementary and annotated so that those reading one part can easily refer to relevant sections in the other. For the clinician interested in common or rare pigment disorders or the principles of teaching about such disorders, this book provides an immediate and complete resource on the biologic bases for these disorders. For the scientist studying the biology of melanocyte function, the book provides a list of disorders that are related to basic biological functions of melanocytes. New features of this Second Edition include: Completely new section on the basic science of pigmentation – explaining the integration of melanocyte functions with other epidermal cells and with various organ systems like the immune system New chapters on pigmentary disorders related to intestinal diseases, the malignant melanocyte, benign proliferations of melanocytes (nevi) and phototherapy with narrow band UV All clinical chapters include the latest genetic findings and advances in therapy More than 400 color images of virtually all clinical disorders The book is ideal for all dermatologists and especially those interested in disorders of pigmentation. It is of particular use for pediatric dermatologists and medical geneticists caring for patients with congenital and genetic pigmentary disorders. This authoritative volume will fill the gap for dermatology training programs that do not have local experts on pigmentation. Basic and cosmetic scientists studying pigmentation and melanocytes will find the science and clinical correlations very useful in showing human significance and relevance to the results of their studies.




Photoreceptor Optics


Book Description

The above consideration indicates that at present many of the experi mental facts on PS in animals can be quantitatively explained within the limits of the "universal" photoreceptor membrane concept. Of course, existence of preferential orientation of the absorbing dipoles in the tubuli of the rhabdomeres can not be totally rejected. We hope that the concept of the "universal" photoreceptor membrane may serve as the useful instrument when dealing with newly discovered properties of visual cells so that true mechanisms of electrical and optical coupling will be searched for instead of assumptions being made on additional properties of the photoreceptor membrane in every new animal under study. 5. Absorption Spectrum of the Universal Photoreceptor Membrane and Spectral Sensitivity of the Photoreceptor 5. 1 Preliminary Notes It seems nearly self-evident that the absorption spectrum of the pho toreceptor membrane coincides exactly with that of the visual pigment it contains. Hence, the membrane must exhibit three bands of absorp tion - the principal band with its peak within the limits of visible spectrum (or a-peak); the secondary band between 340 and 380 nm (S peak); and the third, protein band, in the ultraviolet (UV) at 280 nm (COLLINS et al. , 1952). The main peak of absorption is located within the range 433-575 nm for retinol-based pigments and between 438 and 620 nm for 3-dehydroretinol-based pigments, the position of Amax de pending on many ecological factors.