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Biologics for the Treatment of Rheumatoid Arthritis

Author : Ronald van Vollenhoven

Publisher : Adis

Page : 0 pages

File Size : 17,76 MB

Release : 2016-01-06

Category : Medical

ISBN : 9783319131078

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Book Description

This book provides a comprehensive overview of the available biologic therapies whilst comparing them to standard disease modifying anti-rheumatic drugs, and discusses how best to determine which therapy is most appropriate for an individual patient in the framework of current guidelines. Biologics for the Treatment of Rheumatoid Arthritis is an up-to-date and concise practical guide to the latest therapeutic developments in this field. This book is an invaluable source of topical information for all rheumatologists and health care professionals treating patients with rheumatoid arthritis.



Biologics in Rheumatology

Author : Coziana Ciurtin

Publisher :

Page : 539 pages

File Size : 29,20 MB

Release : 2016

Category : HEALTH & FITNESS

ISBN : 9781634853026

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Book Description

Significant progress has been acquired in the treatment of rheumatic conditions with the introduction of biologic therapies, which has enabled better control of disease activity and improved patients' long-term outcome. Apart from several biologic treatments already licensed for use in autoimmune rheumatic conditions, numerous other agents are currently under investigation. This rapid expansion of the therapeutic armamentarium requires a critical analysis of individual biologic options and their clinical indications, in order to facilitate the optimal use of these new therapies. The authors felt that a comprehensive book revisiting all the evidence available regarding the efficacy, cost-effectiveness and health implications of the use of biologics in rheumatology was needed in order to integrate the clinical, ethical and socio-economic aspects related to their use. This book is aimed at specialist doctors, trainees, nurses and health professionals working in the field of rheumatology. It critically appraises the level of evidence behind the use of biologic agents in diverse autoimmune diseases, comprising separate chapters which focus on rheumatoid arthritis, systemic lupus erythematosus, myositis, systemic sclerosis, Sjogren's syndrome, seronegative spondyloarthropathies, psoriatic arthritis and psoriasis, small, medium and large vessel vasculitis, osteoporosis, and interstitial lung disease associated with rheumatic conditions. In addition, the book explores aspects related to the use of biologic agents, such as ethical considerations of consenting patients to take part in clinical trials with biologics, and adolescent and adult rheumatology nurse perspectives related to patients' benefits of biologic therapies. Particular interest is given to the use of biologics during pregnancy and assessment of their infectious risks. A separate chapter explores the off-target benefits associated with the use of anti-TNF therapies. Several chapters include data about cost-effectiveness, and national and international guidelines for the use of biologic agents in different rheumatic conditions.



Oxford Textbook of Rheumatology

Author : Philip Conaghan

Publisher : Oxford University Press

Page : 1553 pages

File Size : 47,55 MB

Release : 2013-10

Category : Medical

ISBN : 0199642486

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Book Description

A strong clinical emphasis is present throughout this volume from the first section of commonly presenting problems through to the section addressing problems shared with a range of other clinical sub-specialties.



Psoriatic and Reactive Arthritis

Author : Christopher T. Ritchlin

Publisher : Elsevier Health Sciences

Page : 258 pages

File Size : 46,96 MB

Release : 2007-01-01

Category : Medical

ISBN : 0323036228

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Book Description

This new companion to Hochberg et al.'s Rheumatology masterwork focuses on the momentous recent advances in our understanding of the genetics and immunology of psoriatic and reactive arthritis, and their implications for diagnosis and management. Leading international authorities explore new concepts in genetic and pathogenic mechanisms and early diagnosis; provide comprehensive, well-illustrated coverage of clinical features; evaluate the very latest therapeutic options, including biologics; and discuss clinical outcome measures. Examines the very latest pathogenic mechanisms and diagnostic criteria, providing the necessary tools for early diagnosis and monitoring of disease progression. Offers comprehensive coverage of the clinical manifestations of psoriatic and reactive arthritis, including a 'mini atlas' of color plates.Examines the pros and cons of the available therapeutic options, including the very latest biological as well as traditional therapies.Includes practical discussions of clinical outcome measures, delivering ongoing tools for assessment of function, disease activity, and quality of life.



Introduction to Basics of Pharmacology and Toxicology

Author : Abialbon Paul

Publisher : Springer Nature

Page : 1156 pages

File Size : 24,16 MB

Release : 2021-03-13

Category : Medical

ISBN : 9813360097

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Book Description

This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.



Adverse Reactions to Biologics

Author : L. Puig

Publisher : Karger Medical and Scientific Publishers

Page : 120 pages

File Size : 47,76 MB

Release : 2017-11-07

Category : Medical

ISBN : 3318061018

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Book Description

In many areas of medicine physicians still face the great challenge of finding therapies that will meet the patients’ needs. In dermatology the challenge has arisen on multiple fronts through advances in the understanding of the immunopathogenesis of many inflammatory and malignant cutaneous disorders. Breakthroughs, combined with significant developments in targeted immunotherapy, have resulted in improved outcomes as these newer therapies are being used for both approved indications and as off-label therapies for various chronic inflammatory skin disorders and many forms of skin cancer. In the expectation that by truly understanding the safety profile of these targeted therapies patients’ outcomes will be significantly improved, this book offers insights into topics such as adverse reactions, infectious complications and the perioperative use of biologics in psoriasis, immunogenicity of biologic therapies, paradoxical reactions, safety of biologics used to treat autoimmune bullous diseases and primary cutaneous lymphomas, adverse reactions and skin manifestations of therapies targeting melanoma and non-melanoma skin cancer and other neoplastic diseases. Eminent researchers with extensive clinical experience have contributed to this publication, providing an in-depth overview of the latest knowledge in this field.



Safe and Effective Medicines for Children

Author : Institute of Medicine

Publisher : National Academies Press

Page : 432 pages

File Size : 37,96 MB

Release : 2012-10-13

Category : Medical

ISBN : 0309225493

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Book Description

The Best Pharmaceuticals for Children Act (BPCA) and the Pediatric Research Equity Act (PREA) were designed to encourage more pediatric studies of drugs used for children. The FDA asked the IOM to review aspects of pediatric studies and changes in product labeling that resulted from BPCA and PREA and their predecessor policies, as well as assess the incentives for pediatric studies of biologics and the extent to which biologics have been studied in children. The IOM committee concludes that these policies have helped provide clinicians who care for children with better information about the efficacy, safety, and appropriate prescribing of drugs. The IOM suggests that more can be done to increase knowledge about drugs used by children and thereby improve the clinical care, health, and well-being of the nation's children.



Pediatric Rheumatology, an Issue of Rheumatic Disease Clinics

Author : Andreas Reiff

Publisher : Clinics: Internal Medicine

Page : 0 pages

File Size : 34,64 MB

Release : 2013-11-12

Category : Medical

ISBN : 9780323242356

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Book Description

This issue of Rheumatic Disease Clinics teaches you the latest developments and best practices in pediatric rheumatology. Guest edited by Andreas Reiff, topics include juvenile arthritis, juvenile spondyloarthritis, inflammatory bowel disease, vasculitis, scleroderma, eye conditions, and more



Skills in Rheumatology

Author : Hani Almoallim

Publisher : Springer Nature

Page : 562 pages

File Size : 34,37 MB

Release : 2021-01-05

Category : Medical

ISBN : 9811583234

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Book Description

This Open Access book presents practical approaches to managing patients affected by various rheumatological diseases, allowing readers to gain a better understanding of the various clinical expressions and problems experienced by these patients. Discussing rheumatology from an organ systems perspective, it highlights the importance ofdetailed musculoskeletal examinations when treating patients affected by rheumatological diseases. The book first explores the latest diagnostic approaches and offers key tips for accurate musculoskeletal examinations before addressing the various treatment modalities, with a particular focus on the most common joints involved in rheumatoid arthritis: the wrists and the metacarpophalangeal joints (2nd and 3rd). Featuring easy-to-understand flow diagrams and explaining the common medical problems associated with rheumatic disease, such as shortness of breath and anemia, it is not only a valuable resource to rheumatologists, but will also appeal to medical students, junior residents, and primary healthcare physicians.



Rheumatology Drug Review

Author : Donica Liu Baker

Publisher :

Page : 126 pages

File Size : 48,6 MB

Release : 2020-01-18

Category :

ISBN : 9781660800612

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Book Description

Review pharmacology of Rheumatology drugs for board preparation and patient care! Whether you are starting your Rheumatology fellowship, finishing training, or are already an attending in academics or private practice, this will be a useful book for board preparation, clinical practice, and also for patient counseling. Up to date on the latest FDA-approved agents.