Molecular Biology of the Cell
Author :
Publisher :
Page : 0 pages
File Size : 23,48 MB
Release : 2002
Category : Cells
ISBN : 9780815332183
Molecular Biology of Mutagens and Carcinogens
Author : Beatrice Singer
Publisher : Springer Science & Business Media
Page : 352 pages
File Size : 35,37 MB
Release : 2012-12-06
Category : Medical
ISBN : 1461337720
Book Description
This book originated in numerous Gordon Research Conferences and many other meetings of scientists working in chemistry, biophysics, biochemistry, and biology related to mutagenesis and carcinogenesis. It seemed the appro priate time to sit back and summarize the results of several decades of research in laboratories in different countries. We are very grateful to the Rockefeller Foundation for inviting us to formulate and begin writing the book at the Center for International Studies in Bellagio, Italy, where we were Resident Scholars. We are fortunate to have had the assistance of so many colleagues around the world who cheerfully sent original data, figures, and preprints and lis tened patiently to us as we worked out the various conflicting ideas in this fast-moving. field. The names of these scientists are found within the tables, figures, and references. There is one person whose contributions we especially wish to acknowl edge. Professor Heinz Fraenkel-Conrat was present at the inception of this book and throughout the writing encouraged and criticized in apprOximately equal proportion. Finally, his editing and amalgamation of our two styles gave us great comfort. B.S. D.G.
Genes and the Biology of Cancer
Author : Harold Varmus
Publisher : Times Books
Page : 214 pages
File Size : 30,20 MB
Release : 1993-01-01
Category : Medical
ISBN : 9780716750376
Book Description
Discusses advances in cancer research and shows how research into the causes of cancer have led to a greater understanding of the normal biological functioning of cells
The Molecular Biology of Cancer
Author : Harris Busch
Publisher : Academic Press
Page : 657 pages
File Size : 20,79 MB
Release : 2013-10-22
Category : Medical
ISBN : 1483216853
Book Description
The Molecular Biology of Cancer discusses the state of progress in the molecular biology of cancer. The book describes the effects of anticancer agents on nucleolar ultrastructure; the role of chromosomes in the causation and progression of cancer and leukemia; the replication, modification, and repair of DNA. The text also describes the metabolism and utilization of messenger RNA and other high molecular weight RNA and low molecular weight nuclear RNA; the characteristics, structures, and functions of nuclear proteins; and the process of protein synthesis. Nucleotides are reviewed with regard to its biosynthesis, inhibition of synthesis, and development of resistance to inhibitors. The book further tackles the biochemical mechanisms of chemical carcinogenesis; the oncogenic viruses; and the molecular correlation concept. The text also demonstrates phenotypic variability as a manifestation of translational control; and plasmacytomas. Molecular biologists, virologists, pathologists, cell biologists, oncologists, pharmacologists, and students taking related courses will find the book useful.
Molecular Biology of Cancer
Author : Lauren Pecorino
Publisher : Oxford University Press, USA
Page : 365 pages
File Size : 30,12 MB
Release : 2012-04-26
Category : Medical
ISBN : 019957717X
Book Description
Demonstrating how the malfunction of normal molecular pathways and components can lead to cancer, this text explores how our understanding of these defective mechanisms can be harnessed to develop new targeted therapeutic agents.
The Biology of Cancer
Author : Weinberg, Robert A.
Publisher : W.W. Norton & Company
Page : 6 pages
File Size : 11,76 MB
Release : 2013-05-24
Category : Science
ISBN : 0815345283
Book Description
Incorporating the most important advances in the fast-growing field of cancer biology, the text maintains all of its hallmark features. It is admired by students, instructors, researchers, and clinicians around the world for its clear writing, extensive full-color art program, and numerous pedagogical features.
Molecular and Cell Biology of Cancer
Author : Rita Fior
Publisher : Springer
Page : 222 pages
File Size : 41,29 MB
Release : 2019-06-27
Category : Medical
ISBN : 3030118126
Book Description
This textbook takes you on a journey to the basic concepts of cancer biology. It combines developmental, evolutionary and cell biology perspectives, to then wrap-up with an integrated clinical approach. The book starts with an introductory chapter, looking at cancer in a nut shell. The subsequent chapters are detailed and the idea of cancer as a mass of somatic cells undergoing a micro-evolutionary Darwinian process is explored. Further, the main Hanahan and Weinberg “Hallmarks of Cancer” are revisited. In most chapters, the fundamental experiments that led to key concepts, connecting basic biology and biomedicine are highlighted. In the book’s closing section all of these concepts are integrated in clinical studies, where molecular diagnosis as well as the various classical and modern therapeutic strategies are addressed. The book is written in an easy-to-read language, like a one-on-one conversation between the writer and the reader, without compromising the scientific accuracy. Therefore, this book is suited not only for advanced undergraduates and master students but also for patients or curious lay people looking for a further understanding of this shattering disease
Computational Biology Of Cancer: Lecture Notes And Mathematical Modeling
Author : Dominik Wodarz
Publisher : World Scientific
Page : 266 pages
File Size : 24,22 MB
Release : 2005-01-24
Category : Science
ISBN : 9814481874
Book Description
The book shows how mathematical and computational models can be used to study cancer biology. It introduces the concept of mathematical modeling and then applies it to a variety of topics in cancer biology. These include aspects of cancer initiation and progression, such as the somatic evolution of cells, genetic instability, and angiogenesis. The book also discusses the use of mathematical models for the analysis of therapeutic approaches such as chemotherapy, immunotherapy, and the use of oncolytic viruses.
Dynamics of Cancer
Author : Steven A. Frank
Publisher : Princeton University Press
Page : 393 pages
File Size : 44,6 MB
Release : 2018-06-05
Category : Medical
ISBN : 0691186863
Book Description
The onset of cancer presents one of the most fundamental problems in modern biology. In Dynamics of Cancer, Steven Frank produces the first comprehensive analysis of how particular genetic and environmental causes influence the age of onset. The book provides a unique conceptual and historical framework for understanding the causes of cancer and other diseases that increase with age. Using a novel quantitative framework of reliability and multistage breakdown, Frank unifies molecular, demographic, and evolutionary levels of analysis. He interprets a wide variety of observations on the age of cancer onset, the genetic and environmental causes of disease, and the organization of tissues with regard to stem cell biology and somatic mutation. Frank uses new quantitative methods to tackle some of the classic problems in cancer biology and aging: how the rate of increase in the incidence of lung cancer declines after individuals quit smoking, the distinction between the dosage of a chemical carcinogen and the time of exposure, and the role of inherited genetic variation in familial patterns of cancer. This is the only book that presents a full analysis of the age of cancer onset. It is a superb teaching tool and a rich source of ideas for new and experienced researchers. For cancer biologists, population geneticists, evolutionary biologists, and demographers interested in aging, this book provides new insight into disease progression, the inheritance of predisposition to disease, and the evolutionary processes that have shaped organismal design.
Ecology and Evolution of Cancer
Author : Beata Ujvari
Publisher : Academic Press
Page : 292 pages
File Size : 12,10 MB
Release : 2017-02-08
Category : Medical
ISBN : 0128043806
Book Description
Ecology and Evolution of Cancer is a timely work outlining ideas that not only represent a substantial and original contribution to the fields of evolution, ecology, and cancer, but also goes beyond by connecting the interfaces of these disciplines. This work engages the expertise of a multidisciplinary research team to collate and review the latest knowledge and developments in this exciting research field. The evolutionary perspective of cancer has gained significant international recognition and interest, which is fully understandable given that somatic cellular selection and evolution are elegant explanations for carcinogenesis. Cancer is now generally accepted to be an evolutionary and ecological process with complex interactions between tumor cells and their environment sharing many similarities with organismal evolution. As a critical contribution to this field of research the book is important and relevant for the applications of evolutionary biology to understand the origin of cancers, to control neoplastic progression, and to prevent therapeutic failures. - Covers all aspects of the evolution of cancer, appealing to researchers seeking to understand its origins and effects of treatments on its progression, as well as to lecturers in evolutionary medicine - Functions as both an introduction to cancer and evolution and a review of the current research on this burgeoning, exciting field, presented by an international group of leading editors and contributors - Improves understanding of the origin and the evolution of cancer, aiding efforts to determine how this disease interferes with biotic interactions that govern ecosystems - Highlights research that intends to apply evolutionary principles to help predict emergence and metastatic progression with the aim of improving therapies
