Author : James Whisstock
Publisher : Academic Press
Page : 461 pages
File Size : 36,70 MB
Release : 2011-06-11
Category : Science
ISBN : 0123864720
Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases. This volume of Methods in Ezymology is split into 2 parts and comprehensively covers the subject.
Author : James Whisstock
Publisher : Academic Press
Page : 562 pages
File Size : 21,97 MB
Release : 2011-11-16
Category : Medical
ISBN : 0123859506
Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. This volume in the Methods in Enzymology series comprehensively covers this topic. With an international board of authors, this volume covers subjects such as Crystallography of serpins and serpin complexes, Serpins as hormone transporters, and Production of serpins using cell free systems. This volume in the Methods in Enzymology series comprehensively covers the topic of serpins With an international board of authors, this volume covers subjects such as Crystallography of serpins and serpin complexes, Serpins as hormone transporters, and Production of serpins using cell free systems
Author : Alexandra Lucas
Publisher :
Page : 276 pages
File Size : 28,94 MB
Release : 2018
Category : Biochemistry
ISBN : 9781493986453
This volume explores the latest methods used to study and define serpin molecular structure, basic protease inhibition, serpin targets, and the roles of serpin in biology and disease using animal models. The chapters in this book cover topics such as crystallography and phage display, peptide design, phospholipid binding, and thrombus formation to microbiome analysis and development. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and authoritative, Serpins: Methods and Protocols is a valuable resource for researchers and scientists interested in learning more about this evolving field.
Author :
Publisher : Academic Press
Page : 471 pages
File Size : 28,7 MB
Release : 1991-01-28
Category : Technology & Engineering
ISBN : 0080865968
The remarkable expansion of information leading to a deeper understanding of enzymes on the molecular level necessitated the development of this volume which not only introduces new topics to The Enzymes series but presents new information on some covered in Volume I and II of this edition.
Author : Frank C. Church
Publisher : Springer Science & Business Media
Page : 363 pages
File Size : 31,12 MB
Release : 2012-12-06
Category : Science
ISBN : 1461553911
Proceedings of an International Symposium held in Chapel Hill, North Carolina, April 13-16, 1996
Author : James Whisstock
Publisher : Academic Press
Page : 461 pages
File Size : 20,53 MB
Release : 2011-07-18
Category : Medical
ISBN : 0123864712
Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases. This volume of Methods in Ezymology is split into 2 parts and comprehensively covers the subject.
Author : Hari G. Garg
Publisher : Elsevier
Page : 793 pages
File Size : 50,53 MB
Release : 2011-10-10
Category : Science
ISBN : 0080529054
The chemistry, biochemistry and pharmacology of heparin and heparan sulfate have been and continue to be a major scientific undertaking - heparin and its derivative remain important drugs in clinical practice. Chemistry and Biology of Heparin and Heparan Sulfate provides readers with an insight into the chemistry, biology and clinical applications of heparin and heparan sulfate and examines their function in various physiological and pathological conditions. Providing a wealth of useful information, no other tome covers the diversity of topics in the field. Students, doctors, chemists, biochemists, and research scientists will find this book an invaluable source for updating their current knowledge of developments in this area. - Comprehensively reviews all aspects of heparin and heparan sulfate research - Uniquely describes the chemistry, biology and clinical application of heparins and heparan sulfates in one work - Provides an invaluable source of knowledge of current developments for chemists, biochemists, medical doctors, researchers, students and practitioners
Author : Eva Böttcher-Friebertshäuser
Publisher : Springer
Page : 337 pages
File Size : 32,65 MB
Release : 2018-05-22
Category : Medical
ISBN : 3319754742
This book will give an overview on viruses undergoing proteolytic activation through host proteases. The chapters will be organized in three themed parts, the first part describing respective viruses and their characteristics in detail. In the second part the molecular and cellular biology of the proteases involved as well as their physiological functions will be further explored. The third part will contain a chapter on protease inhibitors that are promising tools for antiviral therapy. This book will engage scholars in virology and medical microbiology as well as researchers with an interest in enzymology and protein structure and function relationship.
Author : Margarethe Geiger
Publisher : Springer
Page : 333 pages
File Size : 35,74 MB
Release : 2015-11-13
Category : Science
ISBN : 3319227114
The book provides an comprehensive overview on biology, genetics and cellular functions of serpins (serine protease inhibitors) in health and disease. With over 1000 members serpins are the most diverse family of protease inhibitors. Latest groundbreaking research findings are presented and broaden the understanding on inhibitory and non-inhibitory serpins, not only in mammalian organisms but also in insects, worms, plants and viruses.
Author : Anders Liljas
Publisher : World Scientific
Page : 610 pages
File Size : 29,89 MB
Release : 2016-09-27
Category : Science
ISBN : 9813142499
This book provides a comprehensive coverage of the basic principles of structural biology, as well as an up-to-date summary of some main directions of research in the field. The relationship between structure and function is described in detail for soluble proteins, membrane proteins, membranes, and nucleic acids.There are several books covering protein structure and function, but none that give a complete picture, including nucleic acids, lipids, membranes and carbohydrates, all being of central importance in structural biology.The book covers state-of-the-art research in various areas. It is unique for its breadth of coverage by experts in the fields. The book is richly illustrated with more than 400 color figures to highlight the wide range of structures.
