Bound by Recognition


Book Description

In an era of heightened concern about injustice in relations of identity and difference, political theorists often prescribe equal recognition as a remedy for the ills of subordination. Drawing on the philosophy of Hegel, they envision a system of reciprocal knowledge and esteem, in which the affirming glance of others lets everyone be who they really are. This book challenges the equation of recognition with justice. Patchen Markell mines neglected strands of the concept's genealogy and reconstructs an unorthodox interpretation of Hegel, who, in the unexpected company of Sophocles, Aristotle, Arendt, and others, reveals why recognition's promised satisfactions are bound to disappoint, and even to stifle. Written with exceptional clarity, the book develops an alternative account of the nature and sources of identity-based injustice in which the pursuit of recognition is part of the problem rather than the solution. And it articulates an alternative conception of justice rooted not in the recognition of identity of the other but in the acknowledgment of our own finitude in the face of a future thick with surprise. Moving deftly among contemporary political philosophers (including Taylor and Kymlicka), the close interpretation of ancient and modern texts (Hegel's Phenomenology, Aristotle's Poetics, and more), and the exploration of rich case studies drawn from literature (Antigone), history (Jewish emancipation in nineteenth-century Prussia), and modern politics (official multiculturalism), Bound by Recognition is at once a sustained treatment of the problem of recognition and a sequence of virtuoso studies.




Outstanding Books for the College Bound


Book Description

More than simply a vital collection development tool, this book can help librarians help young adults grow into the kind of independent readers and thinkers who will flourish at college.




Pattern Recognition and String Matching


Book Description

The research and development of pattern recognition have proven to be of importance in science, technology, and human activity. Many useful concepts and tools from different disciplines have been employed in pattern recognition. Among them is string matching, which receives much theoretical and practical attention. String matching is also an important topic in combinatorial optimization. This book is devoted to recent advances in pattern recognition and string matching. It consists of twenty eight chapters written by different authors, addressing a broad range of topics such as those from classifica tion, matching, mining, feature selection, and applications. Each chapter is self-contained, and presents either novel methodological approaches or applications of existing theories and techniques. The aim, intent, and motivation for publishing this book is to pro vide a reference tool for the increasing number of readers who depend upon pattern recognition or string matching in some way. This includes students and professionals in computer science, mathematics, statistics, and electrical engineering. We wish to thank all the authors for their valuable efforts, which made this book a reality. Thanks also go to all reviewers who gave generously of their time and expertise.




Dynamics and Mechanism of DNA-Bending Proteins in Binding Site Recognition


Book Description

Using a novel approach that combines high temporal resolution of the laser T-jump technique with unique sets of fluorescent probes, this study unveils previously unresolved DNA dynamics during search and recognition by an architectural DNA bending protein and two DNA damage recognition proteins. Many cellular processes involve special proteins that bind to specific DNA sites with high affinity. How these proteins recognize their sites while rapidly searching amidst ~3 billion nonspecific sites in genomic DNA remains an outstanding puzzle. Structural studies show that proteins severely deform DNA at specific sites and indicate that DNA deformability is a key factor in site-specific recognition. However, the dynamics of DNA deformations have been difficult to capture, thus obscuring our understanding of recognition mechanisms. The experiments presented in this thesis uncover, for the first time, rapid (~100-500 microseconds) DNA unwinding/bending attributed to nonspecific interrogation, prior to slower (~5-50 milliseconds) DNA kinking/bending/nucleotide-flipping during recognition. These results help illuminate how a searching protein interrogates DNA deformability and eventually “stumbles” upon its target site. Submillisecond interrogation may promote preferential stalling of the rapidly scanning protein at cognate sites, thus enabling site-recognition. Such multi-step search-interrogation-recognition processes through dynamic conformational changes may well be common to the recognition mechanisms for diverse DNA-binding proteins.










Bound for Glory


Book Description

First published in 1943, this autobiography is also a superb portrait of America's Depression years, by the folk singer, activist, and man who saw it all. Woody Guthrie was born in Oklahoma and traveled this whole country over—not by jet or motorcycle, but by boxcar, thumb, and foot. During the journey of discovery that was his life, he composed and sang words and music that have become a national heritage. His songs, however, are but part of his legacy. Behind him Woody Guthrie left a remarkable autobiography that vividly brings to life both his vibrant personality and a vision of America we cannot afford to let die. “Even readers who never heard Woody or his songs will understand the current esteem in which he’s held after reading just a few pages… Always shockingly immediate and real, as if Woody were telling it out loud… A book to make novelists and sociologists jealous.” —The Nation




Biosensors and Bioelectronics


Book Description

Biosensors and Bioelectronics presents the rapidly evolving methodologies that are relevant to biosensors and bioelectronics fabrication and characterization. The book provides a comprehensive understanding of biosensor functionality, and is an interdisciplinary reference that includes a range of interwoven contributing subjects, including electrochemistry, nanoparticles, and conducting polymers. Authored by a team of bioinstrumentation experts, this book serves as a blueprint for performing advanced fabrication and characterization of sensor systems—arming readers with an application-based reference that enriches the implementation of the most advanced technologies in the field. - Features descriptions of functionalized nanocomposite materials and carbon fibre electrode-based biosensors for field and in vivo applications - Presents a range of interwoven contributing subjects, including electrochemistry, nanoparticles, and conducting polymers - Includes more than 70 figures and illustrations that enhance key concepts and aid in retention - Ideal reference for those studying bioreceptors, transducers, bioinstrumentation, nanomaterials, immunosensors, nanotubes, nanoparticles, and electrostatic interactions - Authored by a collaborative team of scientists with more than 50 years of experienced in field research and instruction combined







The Congregationalist


Book Description