Neuroimaging


Book Description

In vivo brain neuroimaging with cutting-edge technologies has achieved great success with high spatial and temporal resolutions. Several distinct medical imaging perspectives such as disease neurobiology, multimodal imaging techniques and applications, large-size clinical trials of neuro-oncology, and bioinformatics with illustrative examples and comprehensive summaries could expand our knowledge of neuroimaging mechanism, methodologies, and applications. This book highlights the possibility and achievement of early detection and multiple neuroimaging biomarkers based on various features for pathophysiological probing and therapeutic prevention. It examines the use of neuroimaging techniques such as magnetic resonance imaging (MRI), electroencephalography (EEG), and near-infrared resonance spectroscopy (NIRS) with specific and innovative biomedical applications. It provides thorough reviews, accurate descriptions, and confirmative evidences of many related important research topics together with up-to-date imaging network management.




Comparative Neuropsychology and Brain Imaging


Book Description

This volume is a special commemorative publication in honor of Professor Dr. Ulrike Halsband, from the University of Freiburg in Germany, on the occasion of her 60th birthday, and includes chapters specially written for the volume, with recent views, reviews and results on such fields as functioneuroanatomytomy, neuropsychology, education, animal behavior, altered states of consciousness, hypnosis and the history of psychology in Germany. The contributors are internationally well-known scholars from academic and clinical institutions abroad in Europe. --




Simultaneous EEG and fMRI


Book Description

One of the major challenges in science is to study and understand the human brain. Numerous methods examining different aspects of brain functions have been developed and employed. To study systemic interactions brain networks in vivo, non-invasive methods such as electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) have been used with great success. However, each of these methods can map only certain, quite selective aspects of brain function while missing others; and the inferences on neuronal processes and information flow are often rather indirect. To overcome these shortcomings of single methods, researchers have attempted to combine methods in order to make optimal use of their advantages while compensating their disadvantages. Hence, it is not surprising that soon after the introduction of fMRI as a neuroimaging method the possibilities of combinations with EEG have been explored. This book is intended to aid researchers who plan to set up a simultaneous EEG-fMRI laboratory and those who are interested in integrating electrophysiological and hemodynamic data. As will be obvious from the different chapters, this is a dynamically developing field in which several approaches are being tested, validated and compared. Currently, there is no one best solution for all problems available, but many promising techniques are emerging. This book shall give a comprehensive overview of these techniques. In addition, it points to open questions and directions for future research.







Optical Methods and Instrumentation in Brain Imaging and Therapy


Book Description

This book provides a comprehensive up-to-date review of optical approaches used in brain imaging and therapy. It covers a variety of imaging approaches including diffuse optical imaging, laser speckle imaging, photoacoustic imaging and optical coherence tomography. A number of laser-based therapeutic techniques are reviewed, including photodynamic therapy, fluorescence guided resection and photothermal therapy. Fundamental principles and instrumentation are discussed for each imaging and therapeutic approach.







The world according to zebrafish: How neural circuits generate behaviour


Book Description

Understanding how the brain functions is one of the most ambitious current scientific goals. This challenge will only be accomplish by a multidisciplinary approach involving genetics, molecular biology, optics, ethology, neurobiology and mathematics and using tractable model systems. The zebrafish larva is a transparent genetically tractable small vertebrate, ideal for the combination state-of-the- art imaging techniques (e.g. two-photon scanning microscopy, single-plane illumination microscopy, spatial light modulator microscopy and lightfield microscopy), bioluminiscence and optogenetics to monitor and manipulate neuronal activity from single specific neurons up to the entire brain, in an intact behaving organism. Furthermore, the zebrafish model offers large and increasing collection of mutant and transgenic lines modelling human brain diseases. With these advantages in hand, the zebrafish larva became in the recent years, a novel animal model to study neuronal circuits and behaviour, taking us closer than ever before to understand how the brain controls behaviour.




Dynamic Brain - from Neural Spikes to Behaviors


Book Description

This volume contains invited and contributed papers presented at the 12th edition of the International Summer School on Neural Networks "Eduardo R. Caianiello," co-organized by the RIKEN BSI (Japan) and the Department of Physics of the U- versity of Salerno (Italy). The 12th edition of the school was directed by Maria Marinaro (University of Salerno), Silvia Scarpetta (University of Salerno) and Yoko Yamaguchi (RIKEN BSI Japan) and hosted in the Ettore Majoranca Center in Erice in Italy. The contributions collected in this book are aimed at providing primarily high-level tutorial coverage of the fields related to neural dynamics, reporting recent experim- tal and theoretical results investigating the role of collective dynamics in hippocampal and parahippocampal regions and in the mammalian olfactory system. This book is devoted to graduate students and researchers with different scientific background (including physics, mathematics, biology, neuroscience, etc.) who wish to learn about brain science beyond the boundary of their fields. Each lecture aimed to include basic guidance in each field. Topics of lectures include the hippocampus and entorhinal cortex dynamics and mammalian olfactory system dynamics, memory and phase coding, mechanisms for spatial navigation and for episodic memory function, oscillations in neural assemblies, cortical up and down states, and related topics where frontier efforts in recent decades have been successfully linked to a remarkable evolution of the field. April 2008 M. Marinaro S. Scarpetta Y. Yamaguchi