Health Risks from Exposure to Low Levels of Ionizing Radiation


Book Description

This book is the seventh in a series of titles from the National Research Council that addresses the effects of exposure to low dose LET (Linear Energy Transfer) ionizing radiation and human health. Updating information previously presented in the 1990 publication, Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR V, this book draws upon new data in both epidemiologic and experimental research. Ionizing radiation arises from both natural and man-made sources and at very high doses can produce damaging effects in human tissue that can be evident within days after exposure. However, it is the low-dose exposures that are the focus of this book. So-called “late” effects, such as cancer, are produced many years after the initial exposure. This book is among the first of its kind to include detailed risk estimates for cancer incidence in addition to cancer mortality. BEIR VII offers a full review of the available biological, biophysical, and epidemiological literature since the last BEIR report on the subject and develops the most up-to-date and comprehensive risk estimates for cancer and other health effects from exposure to low-level ionizing radiation.




Cancer in Atomic Bomb Survivors


Book Description

Follow-up studies of persons exposed to medical radiation have long shown that radiation induces cancer in man. This, coupled with increasing exposure from other sources including occupational and environmental radiations, has resulted in greater recognition of the importance of research on radiation-induced carcinogenesis and risk assessment with a view to radiation protection. One of the well-known late effects of radiation is the increased incidence of leukemia that occurred among atomic bomb survivors beginning two or three years after expo sure. A remarkable increase of solid tumors including cancers of the thyroid, breast and lung was also observed 10 to 20 years after exposure. Thus, many pathological, clinical and epidemiological studies have been made on radiation carcinogenesis in atomic bomb survivors by investigators at the Atomic Bomb Casualty Commission (ABCC), now known as the Radiation Effects Research Foundation (RERF), as well as by the staff of universities in Hiroshima and Nagasaki. Some of the mechanisms involved in radia tion carcinogenesis in man and associated modifying factors, such as age at time of ex posure and sex, have been elucidated by these studies. The results obtained are being used by such agencies as the International Commission on Radiation Protection (ICRP) for risk estimations of radiation exposure. This monograph presents the results realized thus far in these epidemiological and The incidence of radiation-induced cancer among atomic bomb pathological studies.




The Children of Atomic Bomb Survivors


Book Description

Do persons exposed to radiation suffer genetic effects that threaten their yet-to-be-born children? Researchers are concluding that the genetic risks of radiation are less than previously thought. This finding is explored in this volume about the children of atomic bomb survivors in Hiroshima and Nagasakiâ€"the population that can provide the greatest insight into this critical issue. Assembled here for the first time are papers representing more than 40 years of research. These documents reveal key results related to radiation's effects on pregnancy termination, sex ratio, congenital defects, and early mortality of children. Edited by two of the principal architects of the studies, J. V. Neel and W. J. Schull, the volume also offers an important comparison with studies of the genetic effects of radiation on mice. The wealth of technical details will be immediately useful to geneticists and other specialists. Policymakers will be interested in the overall conclusions and discussion of future studies.




Adverse Reproductive Outcomes in Families of Atomic Veterans


Book Description

Over the past several decades, public concern over exposure to ionizing radiation has increased. This concern has manifested itself in different ways depending on the perception of risk to different individuals and different groups and the circumstances of their exposure. One such group are those U.S. servicemen (the "Atomic Veterans" who participated in the atmospheric testing of nuclear weapons at the Nevada Test Site or in the Pacific Proving Grounds, who served with occupation forces in or near Hiroshima and Nagasaki, or who were prisoners of war in or near those cities at the time of, or shortly after, the atomic bombings. This book addresses the feasibility of conducting an epidemiologic study to determine if there is an increased risk of adverse reproductive outcomes in the spouses, children, and grandchildren of the Atomic Veterans.




Effects of Ionizing Radiation


Book Description

In the decades since the atomic bombing of Hiroshima and Nagasaki, economic and political trends have opened avenues for radiation research while breakthroughs in molecular biology have shed light on radiation's effect on the human body. This volume comprehensively reviews what is now known about human exposure to ionizing radiation, with emphasis on unifying the scientific disciplines that inform this topic. Today's most widely recognized experts in the field examine four broad areas: Physics and dosimetry, including the various systems of A-bomb survivor dosimetry, the effect on survivors of subsequent medical radiation, and chromosome aberrations as biomarkers. Cancer statistics and epidemiology, including a historical review of leukemia risk in A-bomb survivors, the incidence of solid cancer and resulting mortality, and the results of studies of workers exposed to low-level radiation. Genetics, including the path from radiation exposure to cellular effects, carcinogenesis, and mutagenesis. Experts discuss the interaction between radiation and other cancer risk factors, review models of radiation-induced cancer, and report on other aspects of molecular biology. Psychological effects of radiation catastrophesâ€"as seen at Hiroshima and Nagasaki, Three Mile Island, and Chernobylâ€"and consequences of the Atomic Bomb Survivors Relief Law.




Health Effects of Exposure to Low Levels of Ionizing Radiation


Book Description

This book reevaluates the health risks of ionizing radiation in light of data that have become available since the 1980 report on this subject was published. The data include new, much more reliable dose estimates for the A-bomb survivors, the results of an additional 14 years of follow-up of the survivors for cancer mortality, recent results of follow-up studies of persons irradiated for medical purposes, and results of relevant experiments with laboratory animals and cultured cells. It analyzes the data in terms of risk estimates for specific organs in relation to dose and time after exposure, and compares radiation effects between Japanese and Western populations.







The Complete Story of Sadako Sasaki


Book Description

**Independent Publisher Book Award (IPPY) Winner** **Middle School Book of the Year-- Northern Lights Book Awards** **Skipping Stones Honor Award Winner** For the first time, middle readers can learn the complete story of the courageous girl whose life, which ended through the effects of war, inspired a worldwide call for peace. In this book, author Sue DiCicco and Sadako's older brother Masahiro tell her complete story in English for the first time--how Sadako's courage throughout her illness inspired family and friends, and how she became a symbol of all people, especially children, who suffer from the impact of war. Her life and her death carry a message: we must have a wholehearted desire for peace and be willing to work together to achieve it. Sadako Sasaki was two years old when the atomic bomb was dropped on her city of Hiroshima at the end of World War II. Ten years later, just as life was starting to feel almost normal again, this athletic and enthusiastic girl was fighting a war of a different kind. One of many children affected by the bomb, she had contracted leukemia. Patient and determined, Sadako set herself the task of folding 1000 paper cranes in the hope that her wish to be made well again would be granted. Illustrations and personal family photos give a glimpse into Sadako's life and the horrors of war. Proceeds from this book are shared equally between The Sadako Legacy NPO and The Peace Crane Project.




Suffering Made Real


Book Description

The atomic bombs dropped on Hiroshima and Nagasaki in August of 1945 unleashed a force as mysterious as it was deadly—radioactivity. In 1946, the United States government created the Atomic Bomb Casualty Commission (ABCC) to serve as a permanent agency in Japan with the official mission of studying the medical effects of radiation on the survivors. The next ten years saw the ABCC's most intensive research on the genetic effects of radiation, and up until 1974 the ABCC scientists published papers on the effects of radiation on aging, life span, fertility, and disease. Suffering Made Real is the first comprehensive history of the ABCC's research on how radiation affected the survivors of the atomic bomb. Arguing that Cold War politics and cultural values fundamentally shaped the work of the ABCC, M. Susan Lindee tells the compelling story of a project that raised disturbing questions about the ethical implications of using human subjects in scientific research. How did the politics of the emerging Cold War affect the scientists' biomedical research and findings? How did the ABCC document and publicly present the effects of radiation? Why did the ABCC refuse to provide medical treatment to the survivors? Through a detailed examination of ABCC policies, archival materials, the minutes of committee meetings, newspaper accounts, and interviews with ABCC scientists, Lindee explores how political and cultural interests were reflected in the day-to-day operations of this controversial research program. Set against a period of conflicting views of nuclear weapons and nuclear power, Suffering Made Real follows the course of a politically charged research program and reveals in detail how politics and cultural values can shape the conduct, results, and uses of science.




American Survivors


Book Description

The little-known history of U.S. survivors of the Hiroshima and Nagasaki atomic bombings reveals captivating trans-Pacific memories of war, illness, gender, and community.