Cancer Stem Cells
Author : Federica Papaccio
Publisher : Springer Nature
Page : 263 pages
File Size : 11,44 MB
Release :
Category :
ISBN : 1071637304
Cancer Stem Cells: New Horizons in Cancer Therapies
Author : Surajit Pathak
Publisher : Springer Nature
Page : 369 pages
File Size : 32,96 MB
Release : 2020-10-17
Category : Medical
ISBN : 9811551200
Book Description
This book discusses the recent developments in the therapeutic implications of cancer stem cells for the effective diagnosis, prognosis, and treatment of cancer. It summarizes the various stem cells of common cancers including colon, pancreas, lungs, prostate, melanoma, and glioblastoma, and reviews the potential role of cancer stem cells in tissue aggressiveness, examining the functional contribution of cancer stem cells in the establishment and recurrence of cancerous tumors. Further, it explores the potential of cancer stem cells as novel therapeutic targets for the treatment and prevention of tumor progression. The book also discusses the various approaches for detecting, isolating, and characterizing different cancer stem cells and signaling pathways that control their replication, survival, and differentiation. Lastly, it explores the key features and mechanisms of drug resistance, chemo-resistance, and radio-resistance in cancer stem cells to improve therapeutic rationale.
Cancer Stem Cells
Author : Lucie Laplane
Publisher : Harvard University Press
Page : 265 pages
File Size : 11,74 MB
Release : 2016-06-06
Category : Medical
ISBN : 0674088743
Book Description
Part IV: The Identity of Stemness and Its Consequences for Cancer Therapies -- Chapter 7. If Stemness Is a Categorical or a Dispositional Property, How Can We Cure Cancers? -- Chapter 8. If Stemness Is a Relational or a Systemic Property, How Can We Cure Cancers? -- Conclusion -- Notes -- References -- Acknowledgments -- Index
The Heterogeneity of Cancer Metabolism
Author : Anne Le
Publisher : Springer
Page : 186 pages
File Size : 36,37 MB
Release : 2018-06-26
Category : Medical
ISBN : 331977736X
Book Description
Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.
Cancer Stem Cells
Author : Sharmila A. Bapat
Publisher : John Wiley & Sons
Page : 274 pages
File Size : 36,32 MB
Release : 2008-10-03
Category : Science
ISBN : 0470391561
Book Description
Because the concept and discoveries of cancer stem cells are relatively new, scientists and researchers need an introduction to this dynamic area. Cancer Stem Cells presents a consolidated account of the research done to date and recent progresses in the studies of cancer stem cells. Such a presentation facilitates a better understanding of and draws attention to stem cell and cancer biology - two fields that enhance, move, and evolve into each other continuously. It provides an informative study in designing approaches to apply stem cell principles to cancer biology while offering an overview of the challenges in developing combination stem and cancer biology targets for therapeutics. This book serves as a primer for new researchers in the field of cancer biology.
Cancer Stem Cells
Author : Vinagolu K. Rajasekhar
Publisher : John Wiley & Sons
Page : 0 pages
File Size : 39,24 MB
Release : 2014-04-14
Category : Science
ISBN : 9781118356166
Book Description
Cancer Stem Cells covers a wide range of topics in cancer stem cell biology, including the functional characteristics of cancer stem cells and how they're generated, where they are localized, the means by which cancer stem cells can be targeted, and how cancer stem cells can be reprogrammed back to normal tissue stem cells. Each chapter begins with a brief historical note and concept summary, followed by a description of the latest basic or clinical advance associated with the topic. Cancer Stem Cells builds systematically from coverage of the basic research stage to an advanced research level, from clinical relevance to therapeutic potential, and will be a valuable resource for professionals in the fields of cancer research and stem cell biology.
Principles of Stem Cell Biology and Cancer
Author : Tarik Regad
Publisher : John Wiley & Sons
Page : 378 pages
File Size : 37,45 MB
Release : 2015-05-06
Category : Science
ISBN : 1118670620
Book Description
Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics Tarik Regad, The John van Geest Cancer Research Centre, Nottingham Trent University, UK, Thomas J. Sayers, Centre for Cancer Research, National Cancer Institute, Frederick, USA and Robert Rees The John van Geest Cancer Research Centre, Nottingham Trent University, UK The field of cancer stem cells is expanding rapidly, with many groups focusing on isolating and identifying cancer stem cell populations. Although some progress has been made developing efficient cancer therapies, targeting cancer stem cells remains one of the important challenges facing the growing stem cell research community. Principles of Stem Cell Biology and Cancer brings together original contributions from international experts in the field to present the very latest information linking stem cell biology and cancer. Divided into two parts, the book begins with a detailed introduction to stem cell biology with a focus on the characterization of these cells, progress that has been made in their identification, as well as future therapeutic applications of stem cells. The second part focuses on cancer stem cells and their role in cancer development, progression and chemo-resistance. This section of the book includes an overview of recent progress concerning therapies targeting cancer stem cells. Features: An authoritative introduction to the link between stem cell biology and cancer. Includes contributions from leading international experts in the field. Well-illustrated with full colour figures throughout. This book will prove an invaluable resource for basic and applied researchers and clinicians working on the development of new cancer treatments and therapies, providing a timely publication of high quality reviews outlining the current progress and exciting future possibilities for stem cell research.
Cancer Stem Cells
Author : William L. Farrar
Publisher : Cambridge University Press
Page : 191 pages
File Size : 16,40 MB
Release : 2010
Category : Medical
ISBN : 0521896282
Book Description
Explores the emerging field of research in cancer stem cells; covers the basic biology, genetic pathways and therapeutic targeting.
Role of Cancer Stem Cells in Cancer Biology and Therapy
Author : Thomas Dittmar
Publisher : CRC Press
Page : 330 pages
File Size : 26,98 MB
Release : 2016-04-19
Category : Medical
ISBN : 1466577363
Book Description
This book summarizes the latest findings about the role of cancer stem cells (CSCs) in cancer biology and how this knowledge could be used for novel anticancer therapies. It provides an overview of CSCs in selected malignancies with particular emphasis on hematopoietic neoplasias. It then reviews the role of CSCs in metastasis formation and initiat
Stem Cells in Cancer: Should We Believe or Not?
Author : Enrique Grande
Publisher : Springer Science & Business
Page : 302 pages
File Size : 44,23 MB
Release : 2014-04-28
Category : Medical
ISBN : 9401787549
Book Description
This volume explores the latest developments in a novel area of molecular biology and a hot topic in the field of oncology: cancer stem cells. These chapters from expert contributing authors present concepts such as the universal stem cell, new molecular pathways, new targeted agents, the different roles that cancer stem cells seem to have according to the organ they are placed in, and the future role that targeting cancer stem cells may have in the management of patients in the clinic. Exploring the latest research including new data from randomized trials, this book examines important proposals over the origin of cancer stem cells such as the possibility that cancer stem cells may arise from mutated stem cells or a fully differentiated cell that may undergo several mutations that drive it back to a stem-like state. The authors consider the role that stem cells seem to have in the onset, development and resistance to classical antitumoral treatments of cancer and discuss possible potential future treatment modalities for the management of advanced cancer patients. The question, "Are stem cells involved in cancer?" may not have a simple answer, but ongoing investigations, in-depth consideration and a broad spectrum of information can be found in this book, allowing the reader to arrive at his or her own answer. This book will appeal to researchers in the field of oncology and cancer research and biomedical scientists with an interest in stem cells.
