Biophysical and Chemical Properties of Collagen: Biomedical Applications: Biomedical Applications


Book Description

Biophysical and Chemical Properties of Collagen: Biomedical Applications provides an introduction to the biophysics and chemistry of collagen and its use as a biomedical material in the rapidly changing fields of biomedical device production, tissue engineering and regenerative medicine. Written by experts in the field, this text will be of interest for researchers as well as lecturers and students.




Bioelectrochemical Systems


Book Description

In the context of wastewater treatment, Bioelectrochemical Systems (BESs) have gained considerable interest in the past few years, and several BES processes are on the brink of application to this area. This book, written by a large number of world experts in the different sub-topics, describes the different aspects and processes relevant to their development. Bioelectrochemical Systems (BESs) use micro-organisms to catalyze an oxidation and/or reduction reaction at an anodic and cathodic electrode respectively. Briefly, at an anode oxidation of organic and inorganic electron donors can occur. Prime examples of such electron donors are waste organics and sulfides. At the cathode, an electron acceptor such as oxygen or nitrate can be reduced. The anode and the cathode are connected through an electrical circuit. If electrical power is harvested from this circuit, the system is called a Microbial Fuel Cell; if electrical power is invested, the system is called a Microbial Electrolysis Cell. The overall framework of bio-energy and bio-fuels is discussed. A number of chapters discuss the basics – microbiology, microbial ecology, electrochemistry, technology and materials development. The book continues by highlighting the plurality of processes based on BES technology already in existence, going from wastewater based reactors to sediment based bio-batteries. The integration of BESs into existing water or process lines is discussed. Finally, an outlook is provided of how BES will fit within the emerging biorefinery area.




Bioelectrosynthesis


Book Description

This volume discusses both the latest experimental research in bioelectrosynthesis and current applications. Beginning with an introduction into the “electrification of biotechnology” as well as the underlying fundamentals, the volume then discusses a wide range of topics based on the interfacing of biotechnological and electrochemical reaction steps. It includes contributions on the different aspects of bioelectrochemical applications for synthesis purposes, i.e. the production of fine and platform chemicals based on enzymatically or microbially catalyzed reactions driven by electric energy. The volume finishes with a summary and outlook chapter which gives an overview of the current status of the field and future perspectives. Edited by experts in the field, and authored by a wide range of international researchers, this volume assesses how research from today’s lab bench can be developed into industrial applications, and is of interest to researchers in academia and industry.




Handbook of Radioactivity Analysis


Book Description

Handbook of Radioactivity Analysis: Radiation Physics and Detectors, Volume One, and Radioanalytical Applications, Volume Two, Fourth Edition, constitute an authoritative reference on the principles, practical techniques and procedures for the accurate measurement of radioactivity - everything from the very low levels encountered in the environment, to higher levels measured in radioisotope research, clinical laboratories, biological sciences, radionuclide standardization, nuclear medicine, nuclear power, and fuel cycle facilities, and in the implementation of nuclear forensic analysis and nuclear safeguards. It includes sample preparation techniques for all types of matrices found in the environment, including soil, water, air, plant matter and animal tissue, and surface swipes.Users will find the latest advances in the applications of radioactivity analysis across various fields, including environmental monitoring, radiochemical standardization, high-resolution beta imaging, automated radiochemical separation, nuclear forensics, and more. - Spans two volumes, Radiation Physics and Detectors and Radioanalytical Applications - Includes a new chapter on the analysis of environmental radionuclides - Provides the latest advances in the applications of liquid and solid scintillation analysis, alpha- and gamma spectrometry, mass spectrometric analysis, Cherenkov counting, flow-cell radionuclide analysis, radionuclide standardization, aerosol analysis, high-resolution beta imaging techniques, analytical techniques in nuclear forensics, and nuclear safeguards - Describes the timesaving techniques of computer-controlled automatic separation and activity analysis of radionuclides - Provides an extensive table of the radiation characteristics of most radionuclides of interest for the radioanalytical chemist




New and Emerging Proteomic Techniques


Book Description

Leading researchers and innovators describe in step-by-step detail the latest techniques that promise to significantly impact the practice of proteomics, as well as its success in developing novel clinical agents. The methods span the entire spectrum of top-down and bottom-up approaches, including microarrays, gels, chromatography, and affinity separations, and address every aspect of the human proteome, both quantitatively and qualitatively. The techniques of protein detection utilized are diverse and range from fluorescence and resonance light scattering to surface plasmon resonance and mass spectrometry. The protocols follow the successful Methods in Molecular BiologyTM series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.




Hardware Hacker


Book Description




Epidermal Growth Factor


Book Description

A comprehensive collection of optimized methods for dissecting the mechanisms that control epidermal growth factors (EGF) and their regulators in both normal and pathological states. These readily reproducible techniques range from the study of purified EGF receptor to complex signaling and processing networks in intact cells, including a chapter on the clinical and pharmacological considerations of their use in cancer therapy. The protocols follow the successful Methods in Molecular BiologyTM series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.




101 Life Skills Games for Children


Book Description

How do you teach tolerance, self-awareness, and responsibility? How can you help children deal with fear, mistrust, or aggression? Play a game with them! Games are an ideal way to help children develop social and emotional skills; they are exciting, relaxing, and fun. 101 LIFE SKILLS GAMES FOR CHILDREN: LEARNING, GROWING, GETTING ALONG (Ages 6-12) is a resource that can help children understand and deal with problems that arise in daily interactions with other children and adults. These games help children develop social and emotional skills and enhance self-awareness. The games address the following issues: dependence, aggression, fear, resentment, disability, accusations, boasting, honesty, flexibility, patience, secrets, conscience, inhibitions, stereotypes, noise, lying, performance, closeness, weaknesses, self confidence, fun, reassurance, love, respect, integrating a new classmate, group conflict. Organized in three main chapters: (I-Games, You-Games and We-Games), the book is well structured and easily accessible. It specifies an objective for every game, gives step-by-step instructions, and offers questions for reflection. It provides possible variations for each game, examples, tips, and ideas for role plays. Each game contains references to appropriate follow-up games and is illustrated with charming drawings.




The Indispensables


Book Description

The acclaimed combat historian and author of The Unknowns details the history of the Marbleheaders and their critical role in the Revolutionary War. On the stormy night of August 29, 1776, the Continental Army faced annihilation after losing the Battle of Brooklyn. The British had trapped George Washington’s army against the East River, and the fate of the Revolution rested upon the soldier-mariners from Marblehead, Massachusetts. One of the country’s first diverse units, they pulled off an “American Dunkirk” and saved the army by navigating the treacherous river to Manhattan. At the right time in the right place, the Marbleheaders, a group of white, black, Hispanic, and Native American soldiers, repeatedly altered the course of events, and their story shines new light on our understanding of the American Revolution. As historian Patrick K. O’Donnell recounts, beginning nearly a decade before the war started, Marbleheaders such as Elbridge Gerry and Azor Orne spearheaded the break with Britain and helped shape the United States through governing, building alliances, seizing British ships, forging critical supply lines, and establishing the origins of the US Navy. The Marblehead Regiment, led by John Glover, became truly indispensable. Marbleheaders battled at Lexington and on Bunker Hill and formed the elite Guard that protected George Washington, foreshadowing today’s Secret Service. Then the special operations–like regiment, against all odds, conveyed 2,400 of Washington’s men across the ice-filled Delaware River on Christmas night of 1776, delivering the surprise attack on Trenton that changed the course of history . . . The Marbleheaders’ story, never fully told before now, makes The Indispensables a vital addition to the literature of the American Revolution. Praise for The Indispensables “Perfectly paced and powerfully wrought, this is the story of common men who gave everything for an ideal—America. The product of meticulous research, The Indispensables is the perfect reminder of who we are, when we need it most.” —Adam Makos, author of the New York Times bestseller A Higher Call “O’Donnell’s gift for storytelling brings the once famous regiment back to life, as he takes readers from the highest war councils to the grime and grit of battle.” —Dr. James Lacey, author of The Washington War “Comprehensive . . . Revolutionary War buffs will delight in the copious details and vivid battle scenes.” —Publishers Weekly “A vivid account of an impressive Revolutionary War unit and a can’t-miss choice for fans of O’Donnell’s previous books.” —Kirkus Review




Alphaherpesviruses


Book Description

Alphaherpesviruses are a fascinating group of DNA viruses that includes important human pathogens such as herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV): the causative agents of cold sores, genital ulcerous disease, and chickenpox/shingles, respectively. A key attribute of these viruses is their ability to establish lifelong latent infection in the peripheral nervous system of the host. Such persistence requires subversion of the host's immune system and intrinsic antiviral defense mechanisms. Understanding the mechanisms of the immune evasion and what triggers viral reactivation is a major challenge for today's researchers. This has prompted enormous research efforts into understanding the molecular and cellular biology of these viruses. This up-to-date and comprehensive volume aims to distill the most important research in this area providing a timely overview of the field. Topics covered include: transcriptional regulation, DNA replication, translational control, virus entry and capsid assembly, the role of microRNAs in infection and oncolytic vectors for cancer therapy. In addition there is coverage of virus-host interactions, including apoptosis, subversion of host protein quality control and DNA damage response pathways, autophagy, establishment and reactivation from latency, interferon responses, immunity and vaccine development. Essential reading for everyone working with alphaherpesviruses and of interest to all virologists working on latent infections.