› › Chemotherapy Of Bacterial Infections

Chemotherapy of Bacterial Infections

Author : R. J. Schnitzer

Publisher : Elsevier

Page : 633 pages

File Size : 16,7 MB

Release : 2013-09-12

Category : Medical

ISBN : 1483273091

Get eBook

Book Description

Experimental Chemotherapy, Volume II: Chemotherapy of Bacterial Infections: Part I is devoted to the history, development, and progress of experimental chemotherapy of bacterial infections. The subject matter has been arranged according to particular groups of compounds, and in a few instances according to specific diseases. The emphasis of Volume II is placed on synthetic compounds. The literature is covered up to the latter part of 1963. It is hoped that this volume will be found useful by investigators and teachers concerned with experimental work on new substances and by physicians and veterinarians who use them. The book opens with a discussion of chemotherapy with antibacterial dyestuffs. This is followed by separate chapters on the mode of action of antibacterial substances such as sulfonamides, penicillins, and other antibiotics; the main lines on which research into antibacterial drugs has developed; and drug resistance for chemotherapy. Subsequent chapters deal with antibacterial chemotherapy with sulfonamides, the experimental pharmacology and toxicology of sulfonamides, the use of nitrofurans as chemotherapeutic agents, and antibacterial agents of limited action. The final chapters discuss experimental chemotherapy of tuberculosis and leprosy.



Antimicrobial Chemotherapy

Author : Roger Finch

Publisher : OUP Oxford

Page : 409 pages

File Size : 25,75 MB

Release : 2012-01-05

Category : Medical

ISBN : 0191628654

Get eBook

Book Description

Antimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy, artificial joint and heart valve surgery. Unlike other classes of medicines, they are vulnerable to resistance from mutations in target microorganisms, and their adverse effects may extend to other patients (increased risk of cross-infection). As a consequence, there is a constant requirement for new agents, as well as practices that ensure the continued effective prescribing of licensed agents. Public awareness and concerns about drug resistant organisms has led to widespread publicity and political action in the UK, Europe and worldwide. The control of drug resistance and the implementation of good prescribing practice are now legal requirements in the UK as a result of the UK Health Act (2008). These fundamental changes underscore the need for a thorough understanding of the advantages and risks associated with specific antibiotic choices. This sixth edition of Antimicrobial Chemotherapy continues to be a valuable resource for undergraduates and graduates requiring a thorough grounding in the scientific basis and clinical application of these drugs. This new edition is updated to include the most recently licensed agents, notably in the treatment of viral infections including HIV/AIDS, and contains new guidance on prescribing practice and infection control practices that limit the development and spread of resistant organisms.



Chemotherapy

Author : J. D. Williams

Publisher : Springer Science & Business Media

Page : 424 pages

File Size : 16,72 MB

Release : 2012-12-06

Category : Medical

ISBN : 1461343461

Get eBook

Book Description

The International Society of Chemotherapy meets every two years to review progress in chemotherapy of infections and of malignant disease. Each meeting gets larger to encompass the extension of chemotherapy into new areas. In some instances, expansion has been rapid, for example in cephalosporins, pen icillins and combination chemotherapy of cancer - in others slow, as in the field of parasitology. New problems of resistance and untoward effects arise; reduction of host toxicity without loss of antitumour activity by new substances occupies wide attention. The improved results with cancer chemotherapy, es pecially in leukaemias, are leading to a greater prevalence of severe infection in patients so treated, pharmacokinetics of drugs in normal and diseased subjects is receiving increasing attention along with related problems of bioavailability and interactions between drugs. Meanwhile the attack on some of the major bacterial infections, such as gonorrhoea and tubercu losis, which were among the first infections to feel the impact of chemotherapy, still continue to be major world problems and are now under attack with new agents and new methods. From this wide field and the 1,000 papers read at the Congress we have produced Proceedings which reflect the variety and vigour of research in this important field of medicine. It was not possible to include all of the papers presented at the Congress but we have attempted to include most aspects of cur rent progress in chemotherapy.



Infections in Cancer Chemotherapy

Author : J. Klastersky

Publisher : Elsevier

Page : 109 pages

File Size : 48,5 MB

Release : 2013-10-22

Category : Medical

ISBN : 1483187772

Get eBook

Book Description

Infections in Cancer Chemotherapy is a collection of paper that details the advancement in the understanding of infections in chemotherapy. The coverage of the text includes aggressive cancer treatment and its role in predisposing to infection; diagnosis of infection in patients with cancer; and non-bacterial infections associated with neoplastic disease. The selection also tackles the protocol for an international prospective trial of initial therapy regimens in neutropenic patients with malignant disease; and the use of gnotobiotics in hematology in improving acute leukemia treatment. The book will be of great interest to oncologists and hematologists.



Special Problems in Chemotherapy

Author : J. D. Williams

Publisher : Springer Science & Business Media

Page : 425 pages

File Size : 23,84 MB

Release : 2012-12-06

Category : Medical

ISBN : 146843120X

Get eBook

Book Description

The International Society of Chemotherapy meets every two years to review progress in chemotherapy of infections and of malignant disease. Each meeting gets larger to encompass the extension of chemotherapy into new areas. In some instances, expansion has been rapid, for example in cephalosporins, pen icillins and combination chemotherapy of cancer - in others slow, as in the field of parasitology. New problems of resistance and untoward effects arise; reduction of host toxicity without loss of antitumour activity by new substances occupies wide attention. The improved results with cancer chemotherapy, es pecially in leukaemias, are leading to a greater prevalence of severe infection in patients so treated, pharmacokinetics of drugs in normal and diseased subjects is receiving increasing attention along with related problems of bioavailability and interactions between drugs. Meanwhile the attack on some of the major bacterial infections, such as gonorrhoea and tubercu losis, which were among the first infections to feel the impact of chemotherapy, still continue to be major world problems and are now under attack with new agents and new methods. From this wide field and the 1,000 papers read at the Congress we have produced Proceedings which reflect the variety and vigour of research in this important field of medicine. It was not possible to include all of the papers presented at the Congress but we have attempted to include most aspects of cur rent progress in chemotherapy.



Viral Infections of Humans

Author : Alfred S. Evans

Publisher : Springer Science & Business Media

Page : 744 pages

File Size : 27,42 MB

Release : 2013-11-11

Category : Medical

ISBN : 1468447270

Get eBook

Book Description

also occurs. New outbreaks of yellow fever have occurred in Colombia and Trinidad and new outbreaks of rift valley fever have occurred in Egypt. Chapter 6, Arenaviruses: The biochemical and physical properties have now been clar ified, and they show a remarkable uniformity in the various viruses constituting the group. The possibility that prenatal infection with LCM may result in hydrocephalus and chorioretinitis has been raised. Serologic surveys have suggested the existence of Lassa virus infection in Guinea, Central African Empire, Mali, Senegal, Cameroon, and Benin, in addition to earlier identification in Nigeria, Liberia, and Sierra Leone. Chapter 7, Coronaviruses: New studies have confirmed the important role of these viruses in common respiratory illnesses of children and adults. The viruses are now known to contain a single positive strand of RNA. About 50% of corona virus infections result in clinical illness. About 5% of common colds are caused by strain DC 43 in winter. Chapter 8, Cytomegalovirus: Sections on pathogenesis of CMV in relation to organ transplantation and mononucleosis, as well as sections on the risk and features of con genital infection and disease, have been expanded. There are encouraging preliminary results with a live CMV vaccine, but the questions of viral persistence and oncogenicity require further evaluation.



Antibacterial Chemotherapy

Author : Sebastian Amyes

Publisher : OUP Oxford

Page : 96 pages

File Size : 13,60 MB

Release : 2010-02-25

Category : Medical

ISBN : 0191576026

Get eBook

Book Description

Although antibiotics are among the most widely used pharmaceuticals, they are also often inappropriately and over-prescribed. Indeed there are increasing predictions that unless we moderate our use of these drugs, bacterial resistance will eventually render them useless. As there are no serious contenders to take the place of antibiotics, including a failure to find new classes of these drugs, it is essential for modern medicine that their efficacy is preserved. Part of the Oxford Infectious Disease Library, this pocketbook is designed to help medical trainees, general prescribers, healthcare workers and students of all biological and medical sciences to understand how antibiotics work, to demonstrate where they might be most appropriate and to make clear the threat of antibiotic resistance. In particular, it will highlight the problems currently seen with bacteria such as MRSA and describe the circumstances leading to their persistence.



Principles and Practice of Cancer Infectious Diseases

Author : Amar Safdar

Publisher : Springer Science & Business Media

Page : 581 pages

File Size : 29,4 MB

Release : 2014-07-08

Category : Medical

ISBN : 1607616440

Get eBook

Book Description

Principles and Practice of Cancer Infectious Diseases is a comprehensive and insightful work dedicated to elucidating the problem of infections in cancer patients. This essential volume reviews common and less often encountered infections, while establishing the difficulties behind preventing, diagnosing, and treating infectious diseases in cancer patients. Key sections are devoted to the presentation of clinical symptoms and the identification of major etiologic agents. A cadre of leading clinicians provide a detailed assessment of the risk factors for various infections, critical strategies in preventing and managing infections, and study of the interactions between the pathogen and host's immune function and inflammatory response. With its in-depth knowledge and concise treatment of the distinct facets of infections in cancer patients, this volume is an indispensible tool for all infectious disease specialists and clinical oncologists.



Antibiotic and Chemotherapy E-Book

Author : Roger G. Finch

Publisher : Elsevier Health Sciences

Page : 913 pages

File Size : 44,24 MB

Release : 2010-11-30

Category : Medical

ISBN : 0702047651

Get eBook

Book Description

Well-respected and widely regarded as the most comprehensive text in the field, Antibiotic and Chemotherapy, 9th Edition by Drs. Finch, Greenwood, Whitley, and Norrby, provides globally relevant coverage of all types of antimicrobial agents used in human medicine, including all antiviral, antiprotozoan and anthelminthic agents. Comprehensively updated to include new FDA and EMEA regulations, this edition keeps you current with brand-new information about antiretroviral agents and HIV, superficial and mucocutaneous myscoses and systemic infections, management of the immunocompromised patient, treatment of antimicrobial resistance, plus coverage of new anti-sepsis agents and host/microbe modulators. Reference is easy thanks to a unique 3-part structure covering general aspects of treatment; reviews of every agent; and details of treatments of particular infections. Offer the best possible care and information to your patients about the increasing problem of multi-drug resistance and the wide range of new antiviral therapies now available for the treatment of HIV and other viral infections. Stay current with 21 new chapters including the latest information on superficial and mucocutaneous mycoses, systemic infections, anti-retroviral agents, and HIV. Get fresh perspectives and insights thanks to 21 newly-authored and extensively re-written chapters. Easily access information thanks to a unique 3-part structure covering general aspects of treatment; reviews of every agent; and details of treatments of particular infections. Apply the latest treatments for anti-microbial organisms such as MRSA, and multi-drug resistant forms of TB, malaria and gonorrhea. Keep up on the latest FDA and EMEA regulations.



Guide to Chemotherapy and Chemoprophylaxis in Bacterial Infections

Author : Y. Z. Abou

Publisher :

Page : 134 pages

File Size : 19,30 MB

Release : 1998

Category : Medical

ISBN : 9789290212256

Get eBook

Book Description

A comprehensive guide to the rational and safe prescribing of antimicrobials in the treatment and prevention of bacterial infections. Now in its second revised edition. the book gives particular attention to the management of infections commonly found in Eastern Mediterranean countries. Addressed to physicians, the guide responds to the urgent need to prevent the misuse of antibiotics, protect against the emergence of resistant bacterial strains and reduce the waste of resources spent on useless treatments. The manual has five chapters. The first explains the general principles of safe and effective antimicrobial therapy, emphasizing the many factors that need to be considered when selecting drugs, doses and modes of administration. The second chapter, which constitutes the core of the manual, provides precise prescribing guidelines for the management of 77 bacterial infections. For each infection, information includes relevant diagnostic advice, the most likely causative organisms listed in the order of frequency, the first-choice drug or combination, followed by alternatives and advice on dosage, mode of administration and duration of therapy. The third chapter outlines essential information about the properties, advantages and limitations of topical preparations for use as disinfectants, antiseptics, cleaning agents and antibiotics. Chemoprophylaxis is covered in the fourth chapter, which describes indications for chemoprophylaxis to prevent wound infection and sepsis in surgery, to prevent selected infections and to prevent bacterial endocarditis. The concluding chapter sets out dosage ranges for 27 commonly used antimicrobials.