Author : Matthias Salathe
Publisher : CRC Press
Page : 451 pages
File Size : 13,59 MB
Release : 2001-07-27
Category : Medical
ISBN : 1482270587
This book details advances in research regarding cilia, mucus, and mucociliary clearance, examining changes in mucus expression and goblet cell metaplasia, and assessing the ability of the mucociliary system to respond to abnormalities. Recognizes that cilia and dynein arms play pivotal roles in developing mammalian embryos! Examines the rol
Author : Kian Fan Chung
Publisher : European Respiratory Society
Page : 365 pages
File Size : 38,38 MB
Release : 2019-06-01
Category : Medical
ISBN : 1849841047
Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.
Author : Wolfgang B. Liedtke, MD, PH.D.
Publisher : CRC Press
Page : 502 pages
File Size : 17,93 MB
Release : 2006-09-29
Category : Medical
ISBN : 1420005847
Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st
Author : United States. Public Health Service. Office of the Surgeon General
Publisher :
Page : 728 pages
File Size : 21,58 MB
Release : 2010
Category : Government publications
ISBN :
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Author : D.F. Rogers
Publisher : Springer Science & Business Media
Page : 408 pages
File Size : 45,42 MB
Release : 1997-09-23
Category : Medical
ISBN : 9783764356910
Conceptually unsavoury, airway mucus is vital to homeostasis in the respiratory tract. In contrast, when abnormal, mucus contributes significantly to the pathophysiology of a number of severe bronchial diseases, including asthma, chronic bronchitis and cystic fibrosis. This volume provides wide ranging and in-depth coverage of the scientific and clinical aspects of airway mucus. It commences with introductory chapters which address the biochemical and molecular biological basis of airway mucus and continues with comprehensive coverage of the various physiological and rheological aspects of respiratory secretions. The clinical aspects of the topic are then considered, with chapters discussing the involvement of mucus secretions in bacterial infection and in hypersecretory diseases of the airway. The volume concludes with a discussion of the therapeutic aspects of the topic, both in terms of the possible approaches to the treatment of mucus hypersecretion and the interaction of these drugs with airway mucus. Written by leading experts in the field, each contribution provides a comprehensive review of its particular subject. Reflecting the latest advances in this important area of respiratory research, this volume will be of great interest to scientists and clinicians working in the field of airway secretions and related areas.
Author :
Publisher : Academic Press
Page : 423 pages
File Size : 48,13 MB
Release : 2009-11-30
Category : Science
ISBN : 0080962823
In recent years, the role of cilia in the study of health, development and disease has been increasingly clear, and new discoveries have made this an exciting and important field of research. This comprehensive volume, a complement to the new three-volume treatment of cilia and flagella by King and Pazour, presents easy-to-follow protocols and detailed background information for researchers working with cilia and flagella. - Covers protocols for primary cilia across several systems and species - Both classic and state-of-the-art methods readily adaptable across model systems, and designed to last the test of time - Relevant to clinicians and scientists working in a wide range of fields
Author : Jaap MJ den Toonder
Publisher : Royal Society of Chemistry
Page : 279 pages
File Size : 20,63 MB
Release : 2013-05-31
Category : Technology & Engineering
ISBN : 1849737096
Cilia are tiny hairs covering biological cells to generate and sense fluid flow. Millions of years of evolution have inspired a novel technology which is barely a decade old. Artificial cilia have been developed to control and sense fluid flow in microscopic systems, presenting new and interesting options for flow control in lab-on-a-chip devices. This appealing link between nature and technology has seen rapid development in the last few years, and this book presents a review of the state-of-the-art in the form of a professional reference book. The editors have pioneered the field, having initiated a major European project on this topic soon after its inception. Active researchers in academia and industry will benefit from the comprehensive nature of this book, while postgraduates and those new to the field will gain a clear understanding of the theory, techniques and applications of artificial cilia.
Author :
Publisher : Academic Press
Page : 643 pages
File Size : 31,18 MB
Release : 1995-08-31
Category : Science
ISBN : 0080859453
Cilia and Flagella presents protocols accessible to all individuals working with eukaryotic cilia and flagella. These recipes delineate laboratory methods and reagents, as well as critical steps and pitfalls of the procedures. The volume covers the roles of cilia and flagella in cell assembly and motility, the cell cycle, cell-cell recognition and other sensory functions, as well as human diseases and disorders. Students, researchers, professors, and clinicians should find the book's combination of "classic" and innovative techniques essential to the study of cilia and flagella.Key Features* A complete guide containing more than 80 concise technical chapters friendly to both the novice and experienced researcher* Covers protocols for cilia and flagella across systems and species from Chlamydomonas and Euglena to mammals* Both classic and state-of-the-art methods readily adaptable across model systems, and designed to last the test of time, including microscopy, electrophoresis, and PCR* Relevant to clinicians interested in respiratory disease, male infertility, and other syndromes, who need to learn biochemical, molecular, and genetic approaches to studying cilia, flagella, and related structures
Author : J. Gordon Betts
Publisher :
Page : 0 pages
File Size : 44,73 MB
Release : 2013-04-25
Category :
ISBN : 9781947172807
Author : Jordan S. Josephson
Publisher : Penguin
Page : 356 pages
File Size : 42,11 MB
Release : 2006-12-05
Category : Health & Fitness
ISBN : 9780399532986
Dr. Josephson's unique five-step program combines the best practices from traditional and alternative medicine to bring relief to the millions who suffer from respiratory problems. Recent research shows that many respiratory diseases are more related than previously thought. Their common, underlying cause is what Dr. Josephson terms "Chronic Airway-Digestive Inflammatory Disease" (CAID). His groundbreaking, proven approach will provide real relief from sinus disease, allergies, asthma, sinus infections, sinus headaches, bronchitis, ear infections, snoring, sleep apnea, GERD, and the acute mold epidemic. Sinus Relief Now will show how to: Maintain proper sinus care Remove mold and other irritants from the home, office, and car Follow a sinus-friendly nutrition program Find the right medications and treatments Experience total-body health
