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Circulating Regulatory Factors and Neuroendocrine Function

Author : Daniela Jezová

Publisher : Springer Science & Business Media

Page : 497 pages

File Size : 15,60 MB

Release : 2013-04-09

Category : Medical

ISBN : 1468457993

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Book Description

During the past several decades, much research effort has gone into the elucidation of the role of neuroendocrine systems as secretory and metabolic regulators of cells of a variety of organs and structures, including the testes, ovaries, adrenals, thyroid, pituitary gland, and mammary glands. However, the role of cells comprising such organs and structures in the modulation of neuroendocrine processes has received considerably less is generally less well appreciated. attention and Nonetheless, it is important that we understand the actions on neuroendocrine systems of substances that reach the brain by way of the vasculature, including hormones, cytokines, toxins, amino acids, drugs, and similar agents. In order to analyze the present state of knowledge on this topic, experimental scientists and clinicians, whose shared interests include actions of circulating agents on the brain, met at a satellite symposium of the XXXI International Congress of Physiological Sciences. This symposium, entitled Circulating Regulatory Factors and Neuroendocrine Function, was held in Smolenice Castle, Czechoslovakia, June 26-July 1, 1989, and reviews delivered at this symposium as invited presentations are published in this volume. Presentations given as free communications have been published separately and are available in Endocrinologia Experimentalis 24: 1-273, 1990.





Biochemistry, Molecular Biology, and Physiology of Phospholipase A2 and Its Regulatory Factors

Author : Anil B. Mukherjee

Publisher : Springer Science & Business Media

Page : 268 pages

File Size : 45,83 MB

Release : 2013-11-11

Category : Science

ISBN : 1461306515

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Book Description

During the past decade there has been a dramatic expansion of our knowledge on phospholipases in general, and phospholipase A2 (PLA2) in particular. Progress in this field has been evident on many fronts, with novel information rapidly accumulating in the literature regarding the chemistry and molecular biology of this enzyme and its role in many important physiological processes. These include cellular signal transduction via the G-protein cycle, and in the generation of many cellular mediators, such as the platelet activating factor (PAF) and the eicosanoids that participate in the initiation and propagation of inflammation, to mention a few. This symposium was organized to obtain an overview of current investigations on this enzyme from the standpoint of its chemistry, molecular biology and physiology. Another important focus of this symposium concerns the regulation of PLA2, including endogenous and synthetic inhibitors and activators of this enzyme. To review these important areas in PLA2 research we invited scientists who made significant contributions in this field. The papers in this volume are organized to emphasize the recent advances in several areas of investigation, including: (I) the structure and mechanism of action of PLA2, (2) mechanism of activation of PLA2, (3) molecular biology, physiology and endogenous inhibitors of this enzyme and finally, (4) clinical investigations emphasizing the pathophysiological role of this enzyme in human diseases. The first article in this volume is by Dr.



Interleukin-1 in the Brain

Author : Nancy J. Rothwell

Publisher : Elsevier

Page : 216 pages

File Size : 48,34 MB

Release : 2013-10-22

Category : Science

ISBN : 1483287769

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Book Description

Interest in interleukin-1 (IL-1) has increased dramatically over the last decade, but has been largely restricted to immunologists, cell biologists and those studying inflammation and cancer. However, it has recently been recognized that the brain directly controls or modulates many aspects of immune function, while molecules classically associated with the immune system, such as interleukin-1, are synthesised within the brain and act directly on the central nervous system to modify local and systemic functions. Thus, this topic is relatively new to neurobiologists, and this book is the first comprehensive description of current knowledge on interleukin-1 in the brain, including its location, synthesis and receptors, actions on behaviour, fever, metabolism, neuroendocrine function, electrical activity of the brain, nerve growth factor, and relationship to clinical indications. The book is organised into three sections. The first reviews the data available on the neural localisation of IL-1 and the nature of its central receptors. The main part of the book examines the different neural effects of IL-1 and the mechanisms which are involved in these actions, comparing IL-1 where possible to other inflammatory cytokines which also have neurotrophic effects. The final section evaluates the possible role of IL-1 in neural plasticity and neuronal degeneration.



Spermatogenesis — Fertilization — Contraception

Author : E. Nieschlag

Publisher : Springer Science & Business Media

Page : 517 pages

File Size : 12,39 MB

Release : 2013-04-17

Category : Medical

ISBN : 3662028158

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Book Description

Investigations into the mechanisms of spennatogenesis, sperm matura tion and fertilization provide the basis of our understanding of male re productive physiology. Since in recent years molecular and cellular en docrinology has provided particularly important contributions to our knowledge, the European Workshops on Molecular and Celluar Endo crinology of the Testis, held regularly during even years since 1980, have become a prominent forum for researchers in the field to discuss recent findings and exchange new ideas. The most recent of these Testis Workshops, the 7th, was held on May 5 - 10, 1992 at Castle Elmau in the Bavarian Alps. The main lectures of this Workshops form the core of this book. In order to provide a broader view of the current status of male re production research, this volume also contains the proceedings of the Schering Foundation Workshop on "Basic Mechanisms of Reproduc tion and Male Fertility Control" which was held in Berlin on October 31 to November 2, 1991. The topics of the two meetings were planned to complement each other. By combining the proceedings of both workshops, it became possible to produce a book that covers a wide spectrum of current highlights in male reproduction research and pro vides the reader with an up-to-date review of the field. The timeliness of the book is emphasized by the fact that it was al ready available when the 7th European Testis Workshop took place.



Healing Trauma

Author : Marion F. Solomon

Publisher : W. W. Norton & Company

Page : 382 pages

File Size : 42,83 MB

Release : 2003-02-25

Category : Psychology

ISBN : 0393703967

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Book Description

Born out of the excitement of a convergence of ideas and passions, this book provides a synthesis of the work of researchers, clinicians, and theoreticians who are leaders in the field of trauma, attachment, and psychotherapy. As we move into the third millennium, the field of mental health is in an exciting position to bring together diverse ideas from a range of disciplines that illuminate our understanding of human experience: neurobiology, developmental psychology, traumatology, and systems theory. The contributors emphasize the ways in which the social environment, including relationships of childhood, adulthood, and the treatment milieu change aspects of the structure of the brain and ultimately alter the mind.



Dissociation and the Dissociative Disorders

Author : Paul F. Dell

Publisher : Routledge

Page : 2132 pages

File Size : 39,48 MB

Release : 2010-11-01

Category : Psychology

ISBN : 1135906025

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Book Description

Winner of ISSTD's 2009 Pierre Janet Writing Award for the best publication on dissociation in 2009! Dissociation and the Dissociative Disorders is a book that has no real predecessor in the dissociative disorders field. It reports the most recent scientific findings and conceptualizations about dissociation; defines and establishes the boundaries of current knowledge in the dissociative disorders field; identifies and carefully articulates the field’s current points of confusion, gaps in knowledge, and conjectures; clarifies the different aspects and implications of dissociation; and sets forth a research agenda for the next decade. In many respects, Dissociation and the Dissociative Disorders both defines and redefines the field.



Brain Control of Responses to Trauma

Author : Nancy J. Rothwell

Publisher : Cambridge University Press

Page : 356 pages

File Size : 47,82 MB

Release : 1994-09-15

Category : Medical

ISBN : 9780521419390

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Book Description

Originally published in 1994, this was the first volume to look in depth at the way the brain responds to trauma and subsequently integrates and influences behavioural, metabolic, neurohumoral, cardiovascular and immune functions. At the time, the role of the brain in the control and integration of the responses to injury and infection was becoming increasingly clear. It had been established that some of these responses, such as fever and neuroendocrine changes, responded to the direct influence of the central nervous system. These, and other advances, provided fresh insights into this area and formed a basis for the more effective understanding and clinical management of trauma patients. In this volume, the authors, all international authorities in their fields, discuss data from experimental and clinical studies and considered the implications of these findings for the treatment of the trauma patient.



Dissociation and the Dissociative Disorders

Author : Martin J. Dorahy

Publisher : Taylor & Francis

Page : 1655 pages

File Size : 31,96 MB

Release : 2022-09-30

Category : Psychology

ISBN : 1000630749

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Book Description

This second edition of the award-winning original text brings together in one volume the current thinking and conceptualizations on dissociation and the dissociative disorders. Comprised of ten parts, starting with historical and conceptual issues, and ending with considerations for the present and future, internationally renowned authors in the trauma and dissociation fields explore different facets of dissociation in pathological and non-clinical guises. This book is designed to be the most comprehensive reference book in the dissociation field and aims to provide a scholarly foundation for understanding dissociation, dissociative disorders, current issues and perspectives within the field, theoretical formulations, and empirical findings. Chapters have been thoroughly updated to include recent developments in the field, including: the complex nature of conceptualization, etiology, and neurobiology; the various manifestations of dissociation in clinical and non-clinical forms; and different perspectives on how dissociation should be understood. This book is essential for clinicians, researchers, theoreticians, students of clinical psychology psychiatry, and psychotherapy, and those with an interest or curiosity in dissociation in the various ways it can be conceived and studied.



Neurobiology of Food and Fluid Intake

Author : Edward M. Stricker

Publisher : Springer Science & Business Media

Page : 588 pages

File Size : 21,67 MB

Release : 2006-05-04

Category : Medical

ISBN : 0306486431

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Book Description

Like previous handbooks, the present volume is an authoritative and up-to-date compendium of information and perspective on the neurobiology of ingestive behaviors. It is intended to be stimulating and informative to the practitioner, whether neophyte or senior scholar. It is also intended to be accessible to others who do not investigate the biological bases of food and ?uid ingestion, who may teach aspects of this material or simply wonder about the current state of the ?eld. To all readers, we present this handbook as a progress report, recognizing that the present state of the ?eld is much farther along than it was the last time a handbook was published, but mindful of the likelihood that it is not as far along as it will be when the next handbook is prepared. This ?eld has witnessed a spectacular accretion of scienti?c information since the ?rst handbook was published in 1967. During the generation of science between then and the publication of the second handbook in 1990, numerous scienti?c reports have substantially changed the perspective and informational base of the ?eld.