Clinical Medicine: Lectures and Essays
Author : Balthazar Walter Foster (Baron Ilkeston.)
Publisher :
Page : 404 pages
File Size : 33,7 MB
Release : 1874
Category :
ISBN :
Clinical Lectures on Klein and Bion
Author : Robin Anderson
Publisher : Routledge
Page : 166 pages
File Size : 40,25 MB
Release : 2014-08-07
Category : Psychology
ISBN : 113491346X
Book Description
Clinical Lectures on Klein and Bion outlines the basic ideas in their thinking and shows in detail how these ideas can be used to tackle a clinical problem. The contributors correct some common misconceptions about Kleinian analysis, while demonstrating the continuity of their everyday work with seminal ideas of Klein and Bion. Originally given as a series of lectures intended to acquaint the general public with recent developments in psychoanalytic thinking and practice, the papers in this book cover the most fundamental ideas put forward by Klein and Bion; child analysis, Klein's use of the concepts of unconscious phantasy, projective identification, the paranoid-schizoid and depressive positions, Bion's study of psychotic thinking, his ideas of the relation between container and contained, and the usefulness of the ideas of reversible perspective in understanding 'as if' personalities. In particular, this book provides an eminently readable and authoritative introduction to some of the most original and controversial concepts ever put forward in psychoanalysis.
Principles and Practice of Clinical Research
Author : John I. Gallin
Publisher : Elsevier
Page : 447 pages
File Size : 26,57 MB
Release : 2011-04-28
Category : Science
ISBN : 0080489567
Book Description
The second edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensure research protocols are well designed and comply with the rigorous regulatory requirements necessary to maximize the safety of research subjects. Complete with sections on the history of clinical research and ethics, copious figures and charts, and sample documents it serves as an excellent companion text for any course on clinical research and as a must-have reference for seasoned researchers.*Incorporates new chapters on Managing Conflicts of Interest in Human Subjects Research, Clinical Research from the Patient's Perspective, The Clinical Researcher and the Media, Data Management in Clinical Research, Evaluation of a Protocol Budget, Clinical Research from the Industry Perspective, and Genetics in Clinical Research *Addresses the vast opportunities for translation of basic science observations to the bedside through clinical research*Delves into data management and addresses how to collect data and use it for discovery*Contains valuable, up-to-date information on how to obtain funding from the federal government
Understanding Clinical Research
Author : Renato D. Lopes
Publisher : McGraw Hill Professional
Page : 262 pages
File Size : 11,64 MB
Release : 2013-05-22
Category : Medical
ISBN : 0071792651
Book Description
A complete guide to understanding and applying clinical research results Ideal for both researchers and healthcare providers Understanding Clinical Research addresses both the operational challenges of clinical trials and the needs of clinicians to comprehend the nuances of research methods to accurately analyze study results. This timely resource covers all aspects of clinical trials--from study design and statistics to regulatory oversight--and it delivers a detailed yet streamlined overview of must-know research topics. The text features an accessible three-part organization that traces the evolution of clinical research and explains the bedrock principles and unique challenges of clinical experimentation and observational research. Reinforcing this content are real-life case examples--drawn from the authors' broad experience--that put chapter concepts into action and contribute to a working knowledge of integral research techniques. FEATURES: The most definitive guide to promoting excellence in clinical research, designed to empower healthcare providers to assess a study's strengths and weaknesses with confidence and apply this knowledge to optimize patient outcomes In-depth coverage of fundamental research methods and protocols from preeminent authorities provides readers with an instructive primer and a springboard for ongoing clinical research education Clear, comprehensive three-part organization: Section One: Evolution of Clinical Research offers a succinct history of clinical trials, drug regulations, and the role of the FDA while covering the impact of information technology and academic research organizations Section Two: Principles of Clinical Experimentation takes you through the typical phases of clinical trials in the development of medical products, from initial human subject research to postapproval surveillance studies Section Three: Observational Research highlights the underlying principles, pitfalls, and methods for case-control studies, cohort studies, registries, and subgroup analyses within randomized trials
The Birth of the Clinic
Author : Michel Foucault
Publisher : Routledge
Page : 344 pages
File Size : 35,94 MB
Release : 2002-11-01
Category : Philosophy
ISBN : 1134955391
Book Description
Foucault's classic study of the history of medicine.
Clinical Lectures and Essays
Author : Sir James Paget
Publisher :
Page : 480 pages
File Size : 44,97 MB
Release : 1875
Category : Clinical medicine
ISBN :
Book Description
Statistics Applied to Clinical Trials
Author : Ton J. Cleophas
Publisher : Springer Science & Business Media
Page : 105 pages
File Size : 10,6 MB
Release : 2013-11-11
Category : Medical
ISBN : 9401595089
Book Description
In 1948 the first randomized controlled trial was published by the English Medical Research Council in the British Medical Journal. Until then, observations had been uncontrolled. Initially, trials frequently did not confirm the hypotheses to be tested. This phenomenon was attributed to low sensitivity due to small samples, as well as inappropriate hypotheses based on biased prior trials. Additional flaws were recognized and, subsequently, were better accounted for: carryover effects due to insufficient washout from previous treatments, time effects due to external factors and the natural history of the condition under study, bias due to asymmetry between treatment groups, lack of sensitivity due to a negative correlation between treatment responses, and so on. Such flaws, mainly of a technical nature, have been largely corrected and led to trials after 1970 being of significantly higher quality. The past decade has focused, in addition to technical aspects, on the need for circumspection in the planning and conducting of clinical trials. As a consequence, prior to approval, clinical trial protocols are now routinely scrutinized by different circumstantial organs, including ethics committees, institutional and federal review boards, national and international scientific organizations, and monitoring committees charged with conducting interim analyses. This book not only explains classical statistical analyses of clinical trials, but also addresses relatively novel issues, including equivalence testing, interim analyses, sequential analyses, and meta-analyses, and provides a framework of the best statistical methods currently available for such purposes. This book is not only useful for investigators involved in the field of clinical trials, but also for all physicians who wish to better understand the data of trials as currently published.
The Comprehensive Guide To Clinical Research
Author : Chris Sauber
Publisher : Independently Published
Page : 218 pages
File Size : 50,91 MB
Release : 2019-04-21
Category :
ISBN : 9781090349521
Book Description
Condensing the most important topics in all of clinical research in an easy to understand presentation. The 20 percent of what you need to know in order to be 80 percent proficient!The authors who have operated various levels of businesses in the clinical research industry since 2005 believe that more practical information pertaining to clinical research needs to be accessible to individuals who are new to the industry or are curious about entering the rewarding world of clinical trials.This book reads in an easy to understand style and is based on proven methods the authors have developed to train their own employees and students of their various clinical research academies throughout the years. Picking this up and absorbing the information will allow anyone to gain much better insight into the complicated dynamics of clinical research. This practical roadmap is all you will need to get started on your clinical trial journey!In this book you will learn about:Regulations and the history as well as evolution of GCP.Clinical Research Site OperationsMonitoring Dynamics and Typical Monitoring VistsCRO ActivitiesSponsor Level DynamicsIndustry VendorsCommon Career Opportunities and Employment Roadmaps
Introduction to Statistics in Pharmaceutical Clinical Trials
Author : Todd A. Durham
Publisher :
Page : 226 pages
File Size : 23,61 MB
Release : 2008-01-01
Category : Mathematics
ISBN : 9780853697145
Book Description
All students of pharmaceutical sciences and clinical research need a solid knowledge and understanding of the nature, methods, application, and importance of statistics. Introduction to Statistics in Pharmaceutical Clinical Trials is an ideal introduction to statistics presented in the context of clinical trials conducted during pharmaceutical drug development. This novel approach both teaches the computational steps needed to conduct analyses and provides a conceptual understanding of how these analyses provide information that forms the rational basis for decision making throughout the drug development process.
Clinical Essays. Asclepiad
Author : Sir Benjamin Ward RICHARDSON
Publisher :
Page : 350 pages
File Size : 23,13 MB
Release : 1862
Category : Medicine
ISBN :
