Eye Banking


Book Description

Corneal transplantation has been performed with increasing success for more than 100 years. In the last 20 years, standards, outcomes and developments in the field of corneal transplantation and eye banking have been discussed at the annual meetings of the European Eye Bank Association (EEBA) to share and promote good practice and guarantee a high level of safety for the recipients. The EEBA standards for donor selection and eye banking provide professional advice and guidance to eye banks and corneal surgeons.This book highlights the history and development of eye banking and all significant steps including the donation, processing and distribution of corneas for transplantation. Additional contributions on the sclera, amnion and retinal pigment epithelium provide further insights into ocular surgery and the future potential for transplantation. This book contributes the essentials in eye banking activities for ophthalmologists and eye bankers as well as for regulatory and legislative authorities.




Eye Banking


Book Description

Until a few years ago, eye banks were only considered as centres for collecting and processing units of human donor eyes. However, eye banks in recent years have changed the process of current corneal transplantation. Although the very first corneal transplantation was conceptualised in the late 18th century, it has taken a century to develop methods and understand the role of human corneas in general. This book gives an insight of worldwide associations and their standard regulations in terms of corneal donations, processes and transplantations. The associations mainly include: Eye Bank Association of America, European Eye Bank Association and Eye Bank Association of Australia and New Zealand. This book also refers to some of the early stages of eye banking and current methods of preservation, including cold and organ culture storage. The current eye banking scenario is changing dramatically in terms of tissue processing. Once, tissues were only collected, stored and shipped for transplantation to the surgeons. Now eye banks have advanced in developing techniques in collaboration with surgeons to introduce more reliable methods of transplantation. This includes standardisation of methods such as DSAEK, UT-DSAEK, pre-loaded grafts and DMEK. Furthermore, this compilation describes different techniques of lamellar keratoplasty, such as anterior and posterior lamellar keratoplasties. Retrieving, storing, processing and transplantation of such lenticules are also discussed in this book. Posterior lamellar graft preparation for selective surgeries like DSAEK and Ultra-Thin DSAEK has been included with relevant clinical approaches. DMEK, which is currently taking corneal transplantation to a different level, has been reported with various graft preparation techniques. The role of eye banks in general for such preparation method is also examined. Additionally, the importance of microbiology in day to day care in the field of corneal transplantation and eye banks exists as a topic within these pages. Eye banks are playing a major role and changing the face of corneal transplantation in terms of new research; whether it be graft preparation for surgeries, preservation, surgical tools, ready-to-use tissues or studying cornea in details using available research tissues, these methods are advancing the field. Eye banks play a major role in tissue selection and correct processing methods. Surgeons are provided with a validated tissue so it makes easier for them to follow the transplantation. Therefore, this book highlights the new concepts in the eye banking field with regards to the standards, regulations, retrieval, preservation and transplantation methods. All of these continue to help aid in the research and development of surgical processes and devices.




DSEK


Book Description

"DSEK: What You Need to Know About Endothelial Keratoplasty provides a comprehensive background of EK, where it is today, and where it is headed in the future. Francis W. Price, MD. who was the first to complete DSEK in the United States, along with Marianne Price, PhD, have designed this text to offer a special emphasis on how to perform surgeries along with preventing and managing complications. In addition, a diverse group of contributing authors provides a wide array of insights and tips for better patient outcomes."--BOOK JACKET.




Corneal Graft Failure


Book Description

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.




Corneal Transplantation


Book Description

- Concise but comprehensive guidebook/handbook - Current and translational information - New concepts of rejection and tolerance - Multimedia display of microsurgical technique




Corneal Surgery


Book Description

Part. 1 Introduction to corneal function and surgery -- Part. 2 Testing and measuring corneal function -- Part. 3 Ocular surface surgery and reconstruction -- Part. 4 Techniques in corneal transplantation -- Part. 5 Special situations in corneal surgery -- Part. 6 Surgical correction of refractive errors.




Foundations of Corneal Disease


Book Description

The field of cornea has seen tremendous advances over the last 40 years—this uniquely comprehensive book will discuss the history of these advances, current best practices in important diseases of the cornea and ocular surface, and examine future directions in diagnosis and management. Written by leading experts, many of whom trained under Claes Henrik Dohlman, MD, PhD, whose influence and many invaluable contributions have defined and shaped the field of cornea, each chapter will reflect the state of the art in the various aspects of cornea. Foundations of Corneal Disease: Past, Present, and Future contains six different sections, opening with an introduction which delves into the evolution of subspecialty training in cornea, and provides a historical perspective of our understanding of ocular surface disease. Section Two addresses perspectives on important corneal and external diseases including infectious keratitis, dry eye, and herpes simplex. Section Three and Section Four address surgery and surgical alternatives, and frontiers in corneal research. Section Six closes this book with a discussion of special topics: imaging the cornea, corneal blindness, eye banking, and clinical trials in dry eye, and explores future directions in this fast-paced field. Foundations of Corneal Disease: Past, Present, and Future contains is an ideal guide for corneal specialists, ophthalmology residents and fellows planning to enter cornea, corneal scientists, and to those in ophthalmology and visual science interested in a comprehensive resource on cornea and the history of this field.




Ocular Surface Disease: Cornea, Conjunctiva and Tear Film


Book Description

Ocular Surface Disease: Cornea, Conjunctiva and Tear Film incorporates current research and the latest management strategies as well as classification systems and treatment paradigms for all forms of ocular surface disease. This is the first comprehensive resource that helps you to meet ocular surface disease challenges effectively using today's best medical and surgical approaches. Get the complete, evidence-based guidance you need to provide optimal care for your patients with ocular surface disease. Implement the latest drug treatments and surgical interventions to provide better outcomes with fewer complications. Hone and expand your surgical skills by watching videos of leading experts performing advanced procedures including ocular surface transplantation techniques; amniotic membrane transplantation; pterygium surgery; lamellar keratoplasty (DALK) in ocular surface disease; and keratoprosthesis surgery. Visualize how to proceed by reviewing detailed, full-color images and consulting new classification systems and treatment paradigms for mild to severe forms of ocular surface disease. Take it with you anywhere! Access the full text, downloadable image library, video clips, and more online at expertconsult.com.




Organ Tissue Engineering


Book Description

The notion of being able to engineer complete organs has inspired an entire generation of researchers. While recent years have brought significant progress in regenerative medicine and tissue engineering, the immense challenges encountered when trying to engineer an entire organ have to be acknowledged. Despite a good understanding of cell phenotypes, cellular niches and cell-to-biomaterial interactions, the formation of tissues composed of multiple cells remains highly challenging. Only a step-by-step approach will allow the future production of a living tissue construct ready for implantation and to augment organ function. In this book, expert authors present the current state of this approach. It offers a concise overview and serves as a great starting point for anyone interested in the application of tissue engineering or regenerative medicine for organ engineering. Each chapter contains a short overview including physiological and pathological changes as well as the current clinical need. The potential cell sources and suitable biomaterials for each organ type are discussed and possibilities to produce organ-like structures are illustrated. The ultimate goal is for the generated small tissues to unfold their full potential in vivo and to serve as a native tissue equivalent. By integrating and evolving, these implants will form functional tissue in-vivo. This book discusses the desired outcome by focusing on well-defined functional readouts. Each chapter addresses the status of clinical translations and closes with the discussion of current bottlenecks and an outlook for the coming years. A successful regenerative medicine approach could solve organ shortage by providing biological substitutes for clinical use - clearly, this merits a collaborative effort.