Craniofacial Embryogenetics and Development


Book Description

The field of embryology has experienced a period of explosive growth since the previous edition of this book was published nearly a decade ago. The insights of genetic expression in determining the unfolding of the embryonic layers have revolutionised our understanding of some of the mechanisms of embryogenesis. As implied by the title of the new edition, Craniofacial Embryogenetics and Development, genetics is linked with embryology in this text. Virtually all embryological development has an underlying genetic component, and the basic science of genetics is the key in uncovering the many mysteries of embryogenesis. The tools of molecular genetics have provided insights into developmental mechanisms that allow us the ability to identify transient regions of genetic expression patterns. Unraveling the precise biochemical and mechanical interactions of discrete regions in the unfolding embryonic components remains a dauntingly-complex challenge to understanding the conversion of the genome into the phenome. The addition of genetic information gleaned from other mammalian species might aid in dissecting human embryology into comprehensible components to understand normal and abnormal development. This new edition is dedicated to this objective and will prove invaluable to plastic and orofacial surgeons, otolaryngologists, orthodontists, neonatal pediatricians, speech pathologists, teratologists, embryologists, and anatomists. Key Features: Provides clinicians with a basic background for assessing and treating craniofacial anomalies. Describes recent technical advances in optical projection tomography, photoacoustic and 3D imaging, small-angle X-ray scattered (SAXS) tomography and morphometrics and their impact on embryogenetics.




Craniofacial Development (Book for Windows & Macintosh)


Book Description

The accompanying CD-ROM includes the complete text and illustrations from the print volume, as well as three-dimensional movies that show reconstructions of embryos.




Craniofacial Embryology


Book Description




Craniofacial Embryogenetics and Development


Book Description

Provides clinicians with a basic background for treating craniofacial anomalies. Includes a CD-ROM with entire text and illustrations of the book in fully searchable PDF files Accompanying CD also contains three-dimensional movies that show reconstructions of embryos




Craniofacial Development, Growth and Evolution


Book Description

"Over the past twenty years craniofacial biology has been revolutionized by major developments in our understanding of the cellular, molecular and genetic mechanisms underlying embryonic development. Many of these advances have been based on animal models, most notably the fruitfly Drosophila, the chick and the mouse. Since these developmental processes have been highly conserved during evolution, this information is relevant not only to understanding normal human development but also to understanding how genetic mutations produce particular malformations or inherited diseases. This book incorporates these discoveries into traditional morphological description of craniofacial development, and in a form accessible to clinicians with an interest in the head and neck." --book cover.




Fundamentals of Craniofacial Malformations


Book Description

This is the first volume in an interdisciplinary three-book series covering the full range of biological, clinical, and surgical aspects in the evaluation, diagnosis, and treatment of patients with craniofacial malformations. This volume opens by considering general topics such as developmental biology and disease classification and then examines in depth the biological basis of the various malformations, including craniosynostoses, cleft-lip and palate with complex orofacial clefts, branchio-oculo-facial syndromes, rare syndromes, soft tissue malformations, and dysgnathia. Psychological aspects, including psychological evaluation methods and therapies and quality of life issues, are then addressed. Finally, all relevant clinical, radiological, and genetic investigations are described and important diagnostic issues are explored. Featuring numerous high-quality illustrations, the book will be of high value for all clinicians, researchers, and postgraduate students who deal with these malformations. The accompanying two volumes describe treatment principles and present in an atlas manner all relevant surgical techniques in detail. The content of this multivolume set, written by the world’s leading research and clinical specialists in their discipline, represents therefore the recent intellect, experience, and state of this medical field.




Biological Mechanisms of Tooth Movement


Book Description

Biological Mechanisms of Tooth Movement This new edition continues to be an authoritative reference to the scientific foundations underpinning clinical orthodontics The newly and thoroughly revised Third Edition of Biological Mechanisms of Tooth Movement delivers a comprehensive reference for orthodontic trainees and specialists. It is fully updated to include new chapters on personalized orthodontics as well as the inflammatory process occurring in the dental and paradental tissues. It is heavily illustrated throughout, making it easier for readers to understand and retain the information discussed within. The topics covered range from bone biology, the effects of mechanical loading on tissues and cells, genetics, tissue remodeling, and the effects of diet, drugs, and systemic diseases. The Third Edition of Biological Mechanisms of Tooth Movement features seven sections that cover subjects such as: The development of biological concepts in orthodontics, including the cellular and molecular biology behind orthodontic tooth movement Mechanics meets biology, including the effects of mechanical loading on hard and soft tissues and cells, and biological reactions to temporary anchorage devices Inflammation and orthodontics, including markers for tissue remodeling in the gingival crevicular fluid and saliva Personalized diagnosis and treatment based on genomic criteria, including the genetic influences on orthodontic tooth movement Rapid orthodontics, including methods to accelerate or decelerate orthodontic tooth movement Perfect for residents and PhD students of orthodontic and periodontal programs, Biological Mechanisms of Tooth Movement is also useful to academics, clinicians, bone biologists, and researchers with an interest in the mechanics and biology of tooth movement.




Handbook of Developmental Cognitive Neuroscience, second edition


Book Description

The second edition of an essential resource to the evolving field of developmental cognitive neuroscience, completely revised, with expanded emphasis on social neuroscience, clinical disorders, and imaging genomics. The publication of the second edition of this handbook testifies to the rapid evolution of developmental cognitive neuroscience as a distinct field. Brain imaging and recording technologies, along with well-defined behavioral tasks—the essential methodological tools of cognitive neuroscience—are now being used to study development. Technological advances have yielded methods that can be safely used to study structure-function relations and their development in children's brains. These new techniques combined with more refined cognitive models account for the progress and heightened activity in developmental cognitive neuroscience research. The Handbook covers basic aspects of neural development, sensory and sensorimotor systems, language, cognition, emotion, and the implications of lifelong neural plasticity for brain and behavioral development. The second edition reflects the dramatic expansion of the field in the seven years since the publication of the first edition. This new Handbook has grown from forty-one chapters to fifty-four, all original to this edition. It places greater emphasis on affective and social neuroscience—an offshoot of cognitive neuroscience that is now influencing the developmental literature. The second edition also places a greater emphasis on clinical disorders, primarily because such research is inherently translational in nature. Finally, the book's new discussions of recent breakthroughs in imaging genomics include one entire chapter devoted to the subject. The intersection of brain, behavior, and genetics represents an exciting new area of inquiry, and the second edition of this essential reference work will be a valuable resource for researchers interested in the development of brain-behavior relations in the context of both typical and atypical development.







Computational Neuroscience in Epilepsy


Book Description

Epilepsy is a neurological disorder that affects millions of patients worldwide and arises from the concurrent action of multiple pathophysiological processes. The power of mathematical analysis and computational modeling is increasingly utilized in basic and clinical epilepsy research to better understand the relative importance of the multi-faceted, seizure-related changes taking place in the brain during an epileptic seizure. This groundbreaking book is designed to synthesize the current ideas and future directions of the emerging discipline of computational epilepsy research. Chapters address relevant basic questions (e.g., neuronal gain control) as well as long-standing, critically important clinical challenges (e.g., seizure prediction). Computational Neuroscience in Epilepsy should be of high interest to a wide range of readers, including undergraduate and graduate students, postdoctoral fellows and faculty working in the fields of basic or clinical neuroscience, epilepsy research, computational modeling and bioengineering. - Covers a wide range of topics from molecular to seizure predictions and brain implants to control seizures - Contributors are top experts at the forefront of computational epilepsy research - Chapter contents are highly relevant to both basic and clinical epilepsy researchers