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Advanced Drug Delivery

Author : Ashim Mitra

Publisher : John Wiley & Sons

Page : 844 pages

File Size : 36,16 MB

Release : 2013-08-26

Category : Medical

ISBN : 1118662849

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Book Description

Provides both fundamentals and new and emerging applications Advanced Drug Delivery brings readers fully up to date with the state of the science, presenting the basics, formulation strategies, and therapeutic applications of advanced drug delivery. The book demonstrates how core concepts of pharmaceutical sciences, chemistry, and molecular biology can be combined and applied in order to spark novel ideas to design and develop advanced drug delivery systems for the treatment of a broad range of human diseases. Advanced Drug Delivery features contributions from an international team of pharmaceutical scientists. Chapters reflect a thorough review and analysis of the literature as well as the authors' firsthand experience developing drug delivery systems. The book is divided into four parts: Part I, Introduction and Basics of Advanced Drug Delivery, explores physiological barriers, stability, transporters, and biomaterials in drug delivery Part II, Strategies for Advanced Drug Delivery, offers tested and proven strategies for advanced delivery of both small molecules and macromolecules Part III, Translational Research of Advanced Drug Delivery, focuses on regulatory considerations and translational applications of advanced drug delivery systems for the treatment of cardiovascular diseases, cancer, sexually transmitted diseases, ophthalmic diseases, and brain diseases Part IV, Future Applications of Advanced Drug Delivery in Emerging Research Areas, examines stem cell research, cell-based therapeutics, tissue engineering, and molecular imaging Each chapter provides objectives and assessment questions to help readers grasp key concepts and assess their knowledge as they progress through the book. Advanced Drug Delivery is recommended for graduates and upper-level undergraduates in the pharmaceutical sciences who need a solid foundation in the basics. It is also recommended for pharmaceutical professionals who want to take advantage of new and emerging applications in advanced drug delivery systems.



Anatomy and Physiology

Author : J. Gordon Betts

Publisher :

Page : 0 pages

File Size : 42,21 MB

Release : 2013-04-25

Category :

ISBN : 9781947172807

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Regulation of Tissue Oxygenation, Second Edition

Author : Roland N. Pittman

Publisher : Biota Publishing

Page : 117 pages

File Size : 42,58 MB

Release : 2016-08-18

Category : Medical

ISBN : 1615047212

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Book Description

This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.



Regulation of Coronary Blood Flow

Author : Michitoshi Inoue

Publisher : Springer Science & Business Media

Page : 330 pages

File Size : 13,44 MB

Release : 2013-11-09

Category : Medical

ISBN : 4431683674

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Book Description

Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.



Text-book of Histology

Author : Philipp Stöhr

Publisher :

Page : 498 pages

File Size : 30,30 MB

Release : 1903

Category : Histology

ISBN :

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Cross-sectional Human Anatomy

Author : David Dean

Publisher : Lippincott Williams & Wilkins

Page : 224 pages

File Size : 49,53 MB

Release : 2000

Category : Medical

ISBN : 9780683303858

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Book Description

Featuring full color cross-sectional images from The Visible Human Pro ject, this new atlas is co-authored by a radiologist and includes orie ntation drawings with corresponding MRIs and CTs. Thus students can un derstand the relationship between anatomy and how it is represented in these imaging modalities. The text includes 100 full color tissue ima ges, 200 line drawings, and 200 magnetic resonance and computed tomogr aphy images. Images are labeled with numbers; the key is on a separate two-page spread to facilitate self-testing.





Handbook of Cardiac Anatomy, Physiology, and Devices

Author : Paul A. Iaizzo

Publisher : Springer

Page : 806 pages

File Size : 32,25 MB

Release : 2015-11-13

Category : Medical

ISBN : 331919464X

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Book Description

This book covers the latest information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Key chapters address animal models for cardiac research, cardiac mapping systems, heart-valve disease and genomics-based tools and technology. Once again, a companion of supplementary videos offer unique insights into the working heart that enhance the understanding of key points within the text. Comprehensive and state-of-the art, the Handbook of Cardiac Anatomy, Physiology and Devices, Third Edition provides clinicians and biomedical engineers alike with the authoritative information and background they need to work on and implement tomorrow’s generation of life-saving cardiac devices.



Pathology of Heart Disease in the Fetus, Infant and Child

Author : Michael T. Ashworth

Publisher : Cambridge University Press

Page : 361 pages

File Size : 31,15 MB

Release : 2019-08-22

Category : Family & Relationships

ISBN : 1107116287

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Book Description

Clearly presents the pathology of heart disease from fetus to adolescence, integrating histology and macroscopy with effects of treatment.