Design of Observational Studies


Book Description

An observational study is an empiric investigation of effects caused by treatments when randomized experimentation is unethical or infeasible. Observational studies are common in most fields that study the effects of treatments on people, including medicine, economics, epidemiology, education, psychology, political science and sociology. The quality and strength of evidence provided by an observational study is determined largely by its design. Design of Observational Studies is both an introduction to statistical inference in observational studies and a detailed discussion of the principles that guide the design of observational studies. Design of Observational Studies is divided into four parts. Chapters 2, 3, and 5 of Part I cover concisely, in about one hundred pages, many of the ideas discussed in Rosenbaum’s Observational Studies (also published by Springer) but in a less technical fashion. Part II discusses the practical aspects of using propensity scores and other tools to create a matched comparison that balances many covariates. Part II includes a chapter on matching in R. In Part III, the concept of design sensitivity is used to appraise the relative ability of competing designs to distinguish treatment effects from biases due to unmeasured covariates. Part IV discusses planning the analysis of an observational study, with particular reference to Sir Ronald Fisher’s striking advice for observational studies, "make your theories elaborate." The second edition of his book, Observational Studies, was published by Springer in 2002.




The Burden of Musculoskeletal Diseases in the United States


Book Description

This study measures the incidence and prevalence of musculoskeletal conditions and projects trends, presenting the latest national data illuminating the physical and economic costs. Several professional organizations concerned with musculoskeletal health and the mission of the U.S. Bone and Joint Decade collaborated to tabulate the data, to educate health care professionals, policy makers and the public.--Publisher's description.




Evidence-based LSP


Book Description

This book presents a number of different perspectives on the central theme of 'evidence' and its interpretation in the study of specialist languages and their various uses. The principal topics include text corpora, citation patterns, some challenging dichotomies, terminology and knowledge management, and specialist translation. Each topic is presented in one of five parts, each with its own introduction. The volume includes contributions from established and new researchers in the field, as well as well-known scholars from other disciplines who bring a fresh eye to LSP studies. The book presents selected papers from LSP2003, the 14th European Symposium on Language for Special Purposes held at the University of Surrey, Guildford, in co-operation with the AILA Scientific Commission on Language for Special Purposes.




Cancer Patient Survival


Book Description




Observational Studies


Book Description

An observational study is an empirical investigation of the effects of treatments, policies, or exposures. It differes from an experiment in that the investigator cannot control the assignments of treatments to subjects. Scientists across a wide range of disciplines undertake such studies, and the aim of this book is to provide a sound statistical account of the principles and methods for the design and analysis of observational studies. Readers are assumed to have a working knowledge of basic probability and statistics, but otherwise the account is reasonably self-contained. Throughout there are extended discussions of actual observational studies to illustrate the ideas discussed. These are drawn from topics as diverse as smoking and lung cancer, lead in children, nuclear weapons testing, and placement programs for students. As a result, many researchers involved in observational studes will find this an invaluable companion to their work.




Methodology and Epistemology for Social Sciences


Book Description

Selections from the work of an influential contributor to the methodology of the social sciences. He treats: measurement, experimental design, epistemology, and sociology of science each section introduced by the editor, Samuel Overman. Annotation copyright Book News, Inc. Portland, Or.




XXXXX


Book Description

xxxxx proposes a radical, new space for artistic exploration, with essential contributions from a diverse range of artists, theorists, and scientists. Combining intense background material, code listings, screenshots, new translation, [the] xxxxx [reader] functions as both guide and manifesto for a thought movement which is radically opposed to entropic contemporary economies. xxxxx traces a clear line across eccentric and wide ranging texts under the rubric of life coding which can well be contrasted with the death drive of cynical economy with roots in rationalism and enlightenment thought. Such philosophy, world as machine, informs its own deadly flipside embedded within language and technology. xxxxx totally unpicks this hiroshimic engraving, offering an dandyish alternative by way of deep examination of software and substance. Life coding is primarily active, subsuming deprecated psychogeography in favour of acute wonderland technology, wary of any assumed transparency. Texts such as Endonomadology, a text from celebrated biochemist and chaos theory pioneer Otto E. Roessler, who features heavily throughout this intense volume, make plain the sadistic nature and active legacy of rationalist thought. At the same time, through the science of endophysics, a physics from the inside elaborated here, a delicate theory of the world as interface is proposed. xxxxx is very much concerned with the joyful elaboration of a new real; software-led propositions which are active and constructive in eviscerating contemporary economic culture. xxxxx embeds Perl Routines to Manipulate London, by way of software artist and Mongrel Graham Harwood, a Universal Dovetailer in the Lisp language from AI researcher Bruno Marchal rewriting the universe as code, and self explanatory Pornographic Coding from plagiarist and author Stewart Home and code art guru Florian Cramer. Software is treated as magical, electromystical, contrasting with the tedious GUI desktop applications and user-led drudgery expressed within a vast ghost-authored literature which merely serves to rehearse again and again the demands of industry and economy. Key texts, which well explain the magic and sheer art of programming for the absolute beginner are published here. Software subjugation is made plain within the very title of media theorist Friedrich Kittler's essay Protected Mode, published in this volume. Media, technology and destruction are further elaborated across this work in texts such as War.pl, Media and Drugs in Pynchon's Second World War, again from Kittler, and Simon Ford's elegant take on J.G Ballard's crashed cars exhibition of 1970, A Psychopathic Hymn. Software and its expansion stand in obvious relation to language. Attacking transparency means examining the prison cell or virus of language; life coding as William Burrough's cutup. And perhaps the most substantial and thorough-going examination is put forward by daring Vienna actionist Oswald Wiener in his Notes on the Concept of the Bio-adapter which has been thankfully unearthed here. Equally, Olga Goriunova's extensive examination of a new Russian literary trend, the online male literature of udaff.com provides both a reexamination of culture and language, and an example of the diversity of xxxxx; a diversity well reflected in background texts ranging across subjects such as Leibniz' monadology, the ur-crash of supreme flaneur Thomas de Quincey and several rewritings of the forensic model of Jack the Ripper thanks to Stewart Home and Martin Howse. xxxxx liberates software from the machinic, and questions the transparency of language, proposing a new world view, a sheer electromysticism which is well explained with reference to the works of Thomas Pynchon in Friedrich Kittler's essay, translated for the first time into English, which closes xxxxx. Further contributors include Hal Abelson, Leif Elggren, Jonathan Kemp, Aymeric Mansoux, and socialfiction.org.




A Life in the Cinema


Book Description