Metal Transporters


Book Description

This volume of Current Topics in Membranes focuses on metal transmembrane transporters and pumps, a recently discovered family of membrane proteins with many important roles in the physiology of living organisms. The book summarizes the most recent advances in the field of metal ion transport and provides a broad overview of the major classes of transporters involved in homeostasis of heavy metals. Various families of the transporters and metal specificities are discussed with the focus on the structural and mechanistic aspects of their function and regulation. The reader will access information obtained through a variety of approaches ranging from X-ray crystallography to cell biology and bioinformatics, which have been applied to transporters identified in diverse biological systems, such as pathogenic bacteria, plants, humans and others. Field is cutting-edge and a lot of the information is new to research community Wide breadth of topic coverage Contributors of high renown and expertise




Encyclopedia of Entomology


Book Description

Bringing together the expertise of over 450 distinguished entomologists from 40 countries, this exhaustive work provides a global overview of insects and their close relatives. It is designed as an introduction to this fascinating group of animals.




Enzymatic Basis of Detoxication Volume 1


Book Description

Enzymatic Basis of Detoxication, Volume I focuses on the catalytic mechanisms and physiological expression of the enzymes that are involved in the detoxication of foreign compounds. The book explores foreign compound metabolism at the level of what specific enzymes can do. This book is organized into three sections and comprised of 17 chapters. The discussion begins with an overview of detoxication and covers both catalytic and non-catalytic removal of foreign substances, along with the general properties of the enzymes that are active in detoxication. The reader is then introduced to the physiological aspects of detoxication, paying particular attention to the kinetic aspects of metabolism and elimination of foreign compounds in animals, human genetic variation in detoxication enzymes, and how such enzymes are induced. The next section focuses on mixed function oxygenase systems and includes chapters on cytochrome P-450 and the detoxication reactions it catalyzes. The book also considers other oxidation-reduction systems, with reference to alcohol dehydrogenase, aldehyde reductase, aldehyde oxidizing enzymes, ketone reductases, xanthine oxidase and aldehyde oxidase, glutathione peroxidase, and superoxide dismutases. The final chapter is devoted to monoamine oxidase, its properties, substrate specificity, inhibitors, kinetics and mechanism, and multiple forms. Pharmacologists, toxicologists, and biochemists will find this book extremely helpful.




An Introduction to Aquatic Toxicology


Book Description

An Introduction to Aquatic Toxicology is an introductory reference for all aspects of toxicology pertaining to aquatic environments. As water sources diminish, the need to understand the effects that contaminants may have on aquatic organisms and ecosystems increases in importance. This book will provide you with a solid understanding of aquatic toxicology, its past, its cutting-edge present and its likely future. An Introduction to Aquatic Toxicology will introduce you to the global issue of aquatic contamination, detailing the major sources of contamination, from where they originate, and their effects on aquatic organisms and their environment. State-of-the-art toxicological topics covered include nanotoxicology, toxicogenomics, bioinformatics, transcriptomics, metabolomics, as well as water management and the toxicological effects of major environmental issues such as algal blooms, climate change and ocean acidification. This book is intended for anyone who wants to know more about the impact of toxicants on aquatic organisms and ecosystems, or to keep up to date with recent and future developments in the field. - Provides with the latest perspectives on the impacts of toxicants on aquatic environments, such as nanotoxicology, toxicogenomics, ocean acidification and eutrophication - Offers a complete overview, beginning with the origins of aquatic toxicology and concluding with potential future challenges - Includes guidance on testing methods and a glossary of aquatic toxicology terms




Cyanide in Biology


Book Description




Cosmic Detox


Book Description

How to cleanse the nine openings of the body for detoxification and self-healing • Explains how to purify the body’s internal environment through mono diets, fasts, and colonic cleanses to prevent degenerative disease and premature aging • Presents a 14-day total-body cleansing guide • Includes chi self-massage and healing sound practices as well as natural recipes for herbal tonics and cleansing flushes Long known by Taoist masters, the body has an innate ability to heal itself, an ability that is hampered by toxins in the food we ingest and energy blockages that arise from illnesses and obstacles in our lives. These blockages transform the body’s energy rivers into a polluted and stagnant swamp--the root of degenerative disease as well as premature aging. Revealing the detoxification and rejuvenation practices of the Taoist sages, Master Mantak Chia and William U. Wei show how to reactivate your body’s self-healing abilities by gradually and safely expelling accumulated toxins through fasting, mono diets, and cleansing the nine openings of the body. Using the practices of chi self-massage and healing sounds along with natural recipes for herbal tonics and cleansing flushes for each of the openings and their related organs, the authors explain how to balance and purify the body’s internal environment through acid and alkaline foods, urine therapy, colonic cleanses, dry skin brushing, ear candling, and energized water. Concluding with a 14-day total-body cleansing program, Cosmic Detox offers tools to keep the energy rivers clean and flowing, preparing the body for higher level Taoist practices as well as enabling healing of our emotional and spiritual bodies.




Detoxication Mechanisms


Book Description




The Detox Prescription


Book Description

The human body has an extraordinary ability to detoxify itself. We rely on this system when we wait for a hangover to lift or recover from a bout of food poisoning. However, cutting-edge science is revealing how toxic exposures can actually affect our genes and lead to conditions such as obesity, diabetes, arthritis, mood disorders, energy, allergies, fertility, and heart disease—all of which are on the rise. The good news is that each of us can optimize this natural cleansing system for better health, greater energy, and efficient weight loss. In The Detox Prescription, Dr. Merrell draws on new research to help readers assess their own toxic risk factors and health deficiencies. Next, he and Mary Beth Augustine, RD, offer more than 75 delicious and nutrient-rich recipes incorporating juices and whole foods, broken into 3-, 7-, and 21-day cleanses. Dr. Merrell's holistic approach also relies on light yoga practices, basic self-care, beginning meditation, and sleep hygiene to reset body, mind, and spiritand take control of our genetic destiny.




Annual Plant Reviews, Insect-Plant Interactions


Book Description

This latest volume in Wiley Blackwell’s prestigious Annual Plant Reviews brings together articles that describe the biochemical, genetic, and ecological aspects of plant interactions with insect herbivores.. The biochemistry section of this outstanding volume includes reviews highlighting significant findings in the area of plant signalling cascades, recognition of herbivore-associated molecular patterns, sequestration of plant defensive metabolites and perception of plant semiochemicals by insects. Chapters in the genetics section are focused on genetic mapping of herbivore resistance traits and the analysis of transcriptional responses in both plants and insects. The ecology section includes chapters that describe plant-insect interactions at a higher level, including multitrophic interactions, investigations of the cost-benefit paradigm and the altitudinal niche-breadth hypothesis, and a re-evaluation of co-evolution in the light of recent molecular research. Written by many of the world’s leading researchers in these subjects, and edited by Claudia Voelckel and Georg Jander, this volume is designed for students and researchers with some background in plant molecular biology or ecology, who would like to learn more about recent advances or obtain a more in-depth understanding of this field. This volume will also be of great use and interest to a wide range of plant scientists and entomologists and is an essential purchase for universities and research establishments where biological sciences are studied and taught. To view details of volumes in Annual Plant Reviews, visit: www.wiley.com/go/apr Also available from Wiley: Plant Defense Dale Walters 9781405175890 Herbicides and Plant Physiology, 2nd Edn Andrew Cobb & John Reade 9781405129350




Caffeine for the Sustainment of Mental Task Performance


Book Description

This report from the Committee on Military Nutrition Research reviews the history of caffeine usage, the metabolism of caffeine, and its physiological effects. The effects of caffeine on physical performance, cognitive function and alertness, and alleviation of sleep deprivation impairments are discussed in light of recent scientific literature. The impact of caffeine consumption on various aspects of health, including cardiovascular disease, reproduction, bone mineral density, and fluid homeostasis are reviewed. The behavioral effects of caffeine are also discussed, including the effect of caffeine on reaction to stress, withdrawal effects, and detrimental effects of high intakes. The amounts of caffeine found to enhance vigilance and reaction time consistently are reviewed and recommendations are made with respect to amounts of caffeine appropriate for maintaining alertness of military personnel during field operations. Recommendations are also provided on the need for appropriate labeling of caffeine-containing supplements, and education of military personnel on the use of these supplements. A brief review of some alternatives to caffeine is also provided.