Author : Jiazhang Lian
Publisher : Frontiers Media SA
Page : 254 pages
File Size : 34,15 MB
Release : 2021-01-20
Category : Science
ISBN : 2889664058
Author : Vijai Singh
Publisher : Academic Press
Page : 0 pages
File Size : 39,40 MB
Release : 2020-02-21
Category : Science
ISBN : 9780128181409
Genome Engineering via CRISPR-Cas9 Systems presents a compilation of chapters from eminent scientists from across the globe who have established expertise in working with CRISPR-Cas9 systems. Currently, targeted genome engineering is a key technology for basic science, biomedical and industrial applications due to the relative simplicity to which they can be designed, used and applied. However, it is not easy to find relevant information gathered in a single source. The book contains a wide range of applications of CRISPR in research of bacteria, virus, algae, plant and mammalian and also discusses the modeling of drosophila, zebra fish and protozoan, among others. Other topics covered include diagnosis, sensor and therapeutic applications, as well as ethical and regulatory issues. This book is a valuable source not only for beginners in genome engineering, but also researchers, clinicians, stakeholders, policy makers, and practitioners interested in the potential of CRISPR-Cas9 in several fields.
Author : Ram Prasad
Publisher : Elsevier
Page : 506 pages
File Size : 12,44 MB
Release : 2018-02-20
Category : Technology & Engineering
ISBN : 0444639888
Crop Improvement through Microbial Biotechnology explains how certain techniques can be used to manipulate plant growth and development, focusing on the cross-kingdom transfer of genes to incorporate novel phenotypes in plants, including the utilization of microbes at every step, from cloning and characterization, to the production of a genetically engineered plant. This book covers microbial biotechnology in sustainable agriculture, aiming to improve crop productivity under stress conditions. It includes sections on genes encoding avirulence factors of bacteria and fungi, viral coat proteins of plant viruses, chitinase from fungi, virulence factors from nematodes and mycoplasma, insecticidal toxins from Bacillus thuringiensis, and herbicide tolerance enzymes from bacteria. - Introduces the principles of microbial biotechnology and its application in crop improvement - Lists various new developments in enhancing plant productivity and efficiency - Explains the mechanisms of plant/microbial interactions and the beneficial use of these interactions in crop improvement - Explores various bacteria classes and their beneficial effects in plant growth and efficiency
Author : Rodolphe Barrangou
Publisher : Springer Science & Business Media
Page : 300 pages
File Size : 22,20 MB
Release : 2012-12-13
Category : Science
ISBN : 364234657X
CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have resulted in a far greater insight into the functions and possible applications of these systems, although many secrets remain to be discovered. In this book, experts summarize the state of the art in this exciting field.
Author : Rodolphe Barrangou
Publisher : John Wiley & Sons
Page : 308 pages
File Size : 24,74 MB
Release : 2022-09-14
Category : Science
ISBN : 168367037X
“An excellent compendium of all things CRISPR from some of the leading minds in the field. With thorough coverage from every angle and beautifully detailed illustrations, this book is not to be missed!” Jennifer A. Doudna, Professor of Chemistry, Biochemistry & Molecular Biology, UC Berkeley; Founder, Innovative Genomics Institute; Nobel Laureate and coinventor of CRISPR technology “This journey through CRISPR biology and several of its breakthrough applications offers an exciting glimpse into one of the most beautiful and compelling fields in the life sciences.” David R. Liu, Director of the Merkin Institute at the Broad Institute of MIT and Harvard; Professor of Chemistry and Chemical Biology at Harvard University; coinventor of base editing and prime editing “A must read! The CRISPR topics, written by world-leading experts, span from the fascinating mechanistic underpinnings to the ingenious applications. One can read from start to finish or pick and choose themes. Either way, the book delivers utterly enjoyable learning!” Bonnie Bassler, Squibb Professor and Chair, Princeton University Department of Molecular Biology; Howard Hughes Medical Institute Investigator CRISPR-Cas systems have revolutionized the science of gene editing and their possible applications continue to expand, from basic research to potentially groundbreaking medical and commercial uses. Led by a distinguished team of editors, CRISPR: Biology and Applications explores the subject matter needed to delve into this fascinating area. Topics covered include: Classification and molecular mechanisms of CRISPR-Cas systems CRISPR-Cas evolution, regulation, expression, and function Uses for gene editing and modulation of gene expression CRISPR-based antimicrobials and phage resistance for medical and industrial purposes Written by internationally renowned authors, CRISPR: Biology and Applications serves as both an introductory guide for those new to the field and an authoritative reference for seasoned researchers whose work touches this evolving and headline- making science.
Author : Hideharu Anazawa
Publisher : Springer Science & Business Media
Page : 302 pages
File Size : 20,65 MB
Release : 2014-02-20
Category : Science
ISBN : 4431546073
Microbial production: From genome design to cell surface engineering affords a comprehensive review of novel technology and approaches being implemented for manufacturing microorganisms, written by specialists in both academia and industry. This book is divided into three sections: the first includes technology for improvement of fermentation strains and many supporting technologies and information; the second examines novel technology useful for analysis of cell activities, analyzing gene function, and designing genomes of producer strains; and finally, a discussion of the practical application of the techniques and success case studies in many fields of bio-production, such as microbiological production, pharmaceuticals, chemicals, foods and cosmetics.
Author : National Research Council
Publisher : National Academies Press
Page : 254 pages
File Size : 15,41 MB
Release : 2004-07-08
Category : Science
ISBN : 0309166152
Assists policymakers in evaluating the appropriate scientific methods for detecting unintended changes in food and assessing the potential for adverse health effects from genetically modified products. In this book, the committee recommended that greater scrutiny should be given to foods containing new compounds or unusual amounts of naturally occurring substances, regardless of the method used to create them. The book offers a framework to guide federal agencies in selecting the route of safety assessment. It identifies and recommends several pre- and post-market approaches to guide the assessment of unintended compositional changes that could result from genetically modified foods and research avenues to fill the knowledge gaps.
Author : Trevor C. Charles
Publisher : Springer
Page : 256 pages
File Size : 31,85 MB
Release : 2017-10-09
Category : Science
ISBN : 3319615106
In this book, the latest tools available for functional metagenomics research are described.This research enables scientists to directly access the genomes from diverse microbial genomes at one time and study these “metagenomes”. Using the modern tools of genome sequencing and cloning, researchers have now been able to harness this astounding metagenomic diversity to understand and exploit the diverse functions of microorganisms. Leading scientists from around the world demonstrate how these approaches have been applied in many different settings, including aquatic and terrestrial habitats, microbiomes, and many more environments. This is a highly informative and carefully presented book, providing microbiologists with a summary of the latest functional metagenomics literature on all specific habitats.
Author : Institute of Medicine
Publisher : National Academies Press
Page : 570 pages
File Size : 33,18 MB
Release : 2011-12-30
Category : Science
ISBN : 0309219396
Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.
Author : Miguel Fernández-Niño
Publisher : BoD – Books on Demand
Page : 106 pages
File Size : 49,97 MB
Release : 2022-02-02
Category : Science
ISBN : 1839696389
The current advances in sequencing, data mining, DNA synthesis, cloning, in silico modeling, and genome editing have opened a new field of research known as Synthetic Genomics. The main goal of this emerging area is to engineer entire synthetic genomes from scratch using pre-designed building blocks obtained by chemical synthesis and rational design. This has opened the possibility to further improve our understanding of genome fundamentals by considering the effect of the whole biological system on biological function. Moreover, the construction of non-natural biological systems has allowed us to explore novel biological functions so far not discovered in nature. This book summarizes the current state of Synthetic Genomics, providing relevant examples in this emerging field.
