Research Awards Index


Book Description




Development of Cardiovascular Systems


Book Description

This volume is a unique overview of cardiovascular development from the cellular to the organ level across a broad range of species. The first section focuses on the molecular, cellular, and integrative mechanisms that determine cardiovascular development. The second section has eight chapters that summarize cardiovascular development in invertebrate and vertebrate systems. The third section discusses the effects of disease and environmental and morphogenetic influences on nonmammalian and mammalian cardiovascular development. It includes strategies for the management of congenital cardiovascular malformations in utero and postnatally.







13th International Conference on Biomedical Engineering


Book Description

th On behalf of the organizing committee of the 13 International Conference on Biomedical Engineering, I extend our w- mest welcome to you. This series of conference began in 1983 and is jointly organized by the YLL School of Medicine and Faculty of Engineering of the National University of Singapore and the Biomedical Engineering Society (Singapore). First of all, I want to thank Mr Lim Chuan Poh, Chairman A*STAR who kindly agreed to be our Guest of Honour to give th the Opening Address amidst his busy schedule. I am delighted to report that the 13 ICBME has more than 600 participants from 40 countries. We have received very high quality papers and inevitably we had to turndown some papers. We have invited very prominent speakers and each one is an authority in their field of expertise. I am grateful to each one of them for setting aside their valuable time to participate in this conference. For the first time, the Biomedical Engineering Society (USA) will be sponsoring two symposia, ie “Drug Delivery S- tems” and “Systems Biology and Computational Bioengineering”. I am thankful to Prof Tom Skalak for his leadership in this initiative. I would also like to acknowledge the contribution of Prof Takami Yamaguchi for organizing the NUS-Tohoku’s Global COE workshop within this conference. Thanks also to Prof Fritz Bodem for organizing the symposium, “Space Flight Bioengineering”. This year’s conference proceedings will be published by Springer as an IFMBE Proceedings Series.




A Study Into the Non-invasive Manipulation of Skin Blood Flow Utilizing Electrotherapy Techniques Integrating Eastern and Western Research to Create an Engaging, Open-ended Classroom Experiences


Book Description

The research to date, of transcutaneous electric nerve stimulation on cutaneous blood flow, is equivocal. The purpose of this report is to review the TENS body of knowledge, in particular synthesizing the literature on acupuncture stimulation of cutaneous blood flow with the two fold goal of creating a protocol to increase skin blood flow through the exogenous application of electrical stimulation, as well as creating an engaging engineering challenge for high school anatomy and physiology students. The hypothesis developed was TENS stimulation with electrode placement on specific acupuncture points would influence cutaneous blood flow as measured using laser Doppler flowmetry. The findings of this project did not support the hypothesis of TENS or Interferential electrical stimulation, in combination with acupuncture points or not, influencing skin blood flow. Perhaps this is due to the physiological differences between glabrous and non-glabrous skin and the different electrical resistances of each dermal layer, nerve stimulation, age and gender of subject or some combination thereof. These equivocal findings may also be the result of inconsistencies in testing protocols, such as subject preconditioning or not, subject's position during administration of stimulation, electrode size and placement to name a few. Ultimately, this report provides a summary of the research to date, as well as outlining how this research could be adapted to supply engaging bio engineering challenges in the classroom including challenges to develop a model for delivering current to muscle; develop a model for skin blood flow management to name a few.







A Non-invasive Method for Measuring Blood Flow Rate in Superficial Veins from a Single Thermal Image


Book Description

Computer vision is a field that includes methods for processing, analyzing, acquiring and understanding images to produce numerical or symbolic information to develop methodologies and solutions for many problems in many fields. Here the concept of computer vision is being used for understanding certain human physiology and behaviors using thermal imaging alone or in conjunction with other imaging modalities. The applications of this work span a wide range of studies in human-machine interfacing vis-á-vis feedback controls that can be used to remotely determine whether a patient is in need of medical assistance or to help integrate young children with learning challenges into a public classroom setting that can require monitoring vital signs and physiological cues without the need for contact-based sensors such as electrocardiogram (ECG) or electroencephalogram (EEG), which limit a subject's physical capabilities during operational scenarios. In this thesis, a general framework is proposed to find an easy way to measure the blood flow using thermal camera to help detecting cots and vascular diseases (Venous disease, Arterial disease). In this thesis, a general framework is proposed to use a thermal image based measurement technique for the volumetric flow rate of a liquid inside a thin tube. This technique makes use of the convection heat transfer dependency between the flow rate and the temperature of the flowing liquid along the tube. The proposed method can be applied to diagnose superficial venous disease non-invasively by measuring the volumetric blood flow rate from a FLIR LWIR single thermal image (Mahmoud et al., 13).