Diffusion-Weighted MR Imaging of the Brain, Head and Neck, and Spine


Book Description

This richly illustrated book, now in an updated and extended third edition, systematically covers the use of diffusion-weighted (DW) MR imaging in all major areas of neuroradiology, including imaging of the head and neck and the spine as well as the brain. The authors guide the reader from the basic principles of DW imaging through to the use of cutting-edge diffusion sequences such as diffusion tensor (DTI) and kurtosis (DKI), fiber tractography, high b value, intravoxel incoherent motion (IVIM), neurite orientation dispersion and density imaging (NODDI), and oscillating gradient spin echo (OGSE). Pathology, pathophysiology, and patient management and treatment are all thoroughly discussed. Since the early descriptions by LeBihan and colleagues of the ability to image and measure the micromovement of water molecules in the brain, diffusion imaging and its derivatives have contributed ever more significantly to the evaluation of multiple disease processes. In comprehensively describing the state of the art in the field, this book will be of high value not only for those who deal routinely with neuro-MR imaging but also for readers who wish to establish a sound basis for understanding diffusion images in the hope of extending these principles into more exotic areas of neuroimaging.




Diffusion MRI Outside the Brain


Book Description

Recent advances in MR technology permit the application of diffusion MRI outside of the brain. In this book, the authors present cases drawn from daily clinical practice to illustrate the role of diffusion sequences, along with other morphological and functional MRI information, in the work-up of a variety of frequently encountered oncological and non-oncological diseases. Breast, musculoskeletal, whole-body, and other applications are covered in detail, with careful explanation of the pros and cons of diffusion MRI in each circumstance. Quantification and post-processing are discussed, and advice is provided on how to acquire state of the art images, and avoid artifacts, when using 1.5- and 3-T magnets. Applications likely to emerge in the near future, such as for screening, are also reviewed. The practical approach adopted by the authors, combined with the wealth of high-quality illustrations, ensure that this book will be of great value to practitioners.




Diffusion MRI


Book Description

Diffusion MRI remains the most comprehensive reference for understanding this rapidly evolving and powerful technology and is an essential handbook for designing, analyzing, and interpreting diffusion MR experiments. Diffusion imaging provides a unique window on human brain anatomy. This non-invasive technique continues to grow in popularity as a way to study brain pathways that could never before be investigated in vivo. This book covers the fundamental theory of diffusion imaging, discusses its most promising applications to basic and clinical neuroscience, and introduces cutting-edge methodological developments that will shape the field in coming years. Written by leading experts in the field, it places the exciting new results emerging from diffusion imaging in the context of classical anatomical techniques to show where diffusion studies might offer unique insights and where potential limitations lie. - Fully revised and updated edition of the first comprehensive reference on a powerful technique in brain imaging - Covers all aspects of a diffusion MRI study from acquisition through analysis to interpretation, and from fundamental theory to cutting-edge developments - New chapters covering connectomics, advanced diffusion acquisition, artifact removal, and applications to the neonatal brain - Provides practical advice on running an experiment - Includes discussion of applications in psychiatry, neurology, neurosurgery, and basic neuroscience - Full color throughout




Diffusion MRI


Book Description

Professor Derek Jones, a world authority on diffusion MRI, has assembled most of the world's leading scientists and clinicians developing and applying diffusion MRI to produce an authorship list that reads like a "Who's Who" of the field and an essential resource for those working with diffusion MRI. Destined to be a modern classic, this definitive and richly illustrated work covers all aspects of diffusion MRI from basic theory to clinical application. Oxford Clinical Neuroscience is a comprehensive, cross-searchable collection of resources offering quick and easy access to eleven of Oxford University Press's prestigious neuroscience texts. Joining Oxford Medicine Online these resources offer students, specialists and clinical researchers the best quality content in an easy-to-access format.




Anisotropy Across Fields and Scales


Book Description

This open access book focuses on processing, modeling, and visualization of anisotropy information, which are often addressed by employing sophisticated mathematical constructs such as tensors and other higher-order descriptors. It also discusses adaptations of such constructs to problems encountered in seemingly dissimilar areas of medical imaging, physical sciences, and engineering. Featuring original research contributions as well as insightful reviews for scientists interested in handling anisotropy information, it covers topics such as pertinent geometric and algebraic properties of tensors and tensor fields, challenges faced in processing and visualizing different types of data, statistical techniques for data processing, and specific applications like mapping white-matter fiber tracts in the brain. The book helps readers grasp the current challenges in the field and provides information on the techniques devised to address them. Further, it facilitates the transfer of knowledge between different disciplines in order to advance the research frontiers in these areas. This multidisciplinary book presents, in part, the outcomes of the seventh in a series of Dagstuhl seminars devoted to visualization and processing of tensor fields and higher-order descriptors, which was held in Dagstuhl, Germany, on October 28-November 2, 2018.




Magnetic Resonance Imaging of the Brain and Spine


Book Description

Established as the leading textbook on imaging diagnosis of brain and spine disorders, Magnetic Resonance Imaging of the Brain and Spine is now in its Fourth Edition. This thoroughly updated two-volume reference delivers cutting-edge information on nearly every aspect of clinical neuroradiology. Expert neuroradiologists, innovative renowned MRI physicists, and experienced leading clinical neurospecialists from all over the world show how to generate state-of-the-art images and define diagnoses from crucial clinical/pathologic MR imaging correlations for neurologic, neurosurgical, and psychiatric diseases spanning fetal CNS anomalies to disorders of the aging brain. Highlights of this edition include over 6,800 images of remarkable quality, more color images, and new information using advanced techniques, including perfusion and diffusion MRI and functional MRI. A companion Website will offer the fully searchable text and an image bank.







Imaging in Oncology


Book Description

This pertinently illustrated and well referenced text serves as an up-to-date, attractive book of oncologic imaging for radiologists, oncologists, radiation therapists and others involved in oncologic care. This volume, with chapter contributions from world-renowned experts, provides clinical and research information that underpins accurate interpretation and sensible use of cancer imaging. The book also highlights new developments and advances in oncologic imaging.




Intravoxel Incoherent Motion (IVIM) MRI


Book Description

Intravoxel incoherent motion (IVIM) refers to translational movements which within a given voxel and during the measurement time present a distribution of speeds in orientation and/or amplitude. The concept was introduced in 1986 together with the foundation of diffusion MRI because it had been realized that flow of blood in capillaries (perfusion) would mimic a diffusion process and impact diffusion MRI measurements. IVIM-based perfusion MRI, which does not require injection of any tracer or contrast agent, has been first investigated in the brain, but is now experiencing a remarkable revival for applications throughout the body, especially for oncologic applications, from diagnosis to treatment monitoring. This book addresses a number of highly topical aspects of the field from leading authorities, introducing the concepts behind IVIM MRI, outlining related methodological issues, and summarizing its current usage and potential for clinical applications. It also presents future research directions, both in terms of methodological development and clinical application fields, extending to new, non-perfusion applications of IVIM MRI, such as virtual MR elastography.




Brain Network Analysis


Book Description

This coherent mathematical and statistical approach aimed at graduate students incorporates regression and topology as well as graph theory.