Dispersion of Powders


Book Description

Teaching the fundamental knowledge required for successful dispersion of powders in a liquid, this book covers a host of topics -- from recent advances to industrial applications. In 15 chapters it supports formulation chemists in preparing a suspension in a more rational way, by applying the principles of colloid and interface science, while at the same time enabling the research scientist to discover new methods for preparing stable suspensions. Essential reading for those working in the pharmaceutical, cosmetic, food, paint, ceramic and agricultural industries.







Surface and Colloid Chemistry in Advanced Ceramics Processing


Book Description

Emphasizes the importance of surface and colloid chemistry in the manufacture of high-performance ceramics. Examines processing-property relationships, powderproductionandcharacte6zation,the dispersion properties of powders in liquids, the rheology of concentrated suspensions, and the surface and colloid chemistry aspects of the most widely used forming methods.




Design and Processing of Particulate Products


Book Description

A unique text providing comprehensive coverage of fundamental particle science, processing and technology. Including quantitative tools, real-world case studies and end-of-chapter problems, it is ideal for students in engineering and applied sciences, as well as for practitioners in a range of industries manufacturing particulate products.




Particle Size Measurements


Book Description

This book focuses on the practical aspects of particle size measurement: a major difference with existing books, which have a more theoretical approach. Of course, the emphasis still lies on the measurement techniques. For optimum application, their theoretical background is accompanied by quantitative quality aspects, limitations and problem identification. In addition the book covers the phenomena of sampling and dispersion of powders, either of which may be dominant in the overall analysis error. Moreover, there are chapters on the general aspects of quality for particle size analysis, quality management, reference materials and written standards, in- and on-line measurement, definitions and multilingual terminology, and on the statistics required for adequate interpretation of results. Importantly, a relation is made to product performance, both during processing as well as in final application. In view of its set-up, this book is well suited to support particle size measurement courses.




Practical Dispersion


Book Description

Ein Handbuch für die Praxis der Dispersionstechnologie: Weitverstreute Daten aus der Literatur, technische Details und ausgewählte theoretische Grundlagen wurden zu einer übersichtlichen, gut verständlichen Darstellung aufbereitet, die nicht mit Mathematik und komplizierten Zusammenhängen überfrachtet ist. An zahlreichen Beispielen wird erklärt, wie sich verschiedene Dispersionszustände in den Eigenschaften des Produkts widerspiegeln; die Wirkung eines Dispersionsmittels wird auf stoffliche Aspekte, nicht Handelsnamen zurückgeführt. Der Anwender wird in die Lage versetzt, 'seine' Dispersionen gezielt zu verändern, um mechanischen, chemischen und ökologischen Anforderungen der Kunden gerecht zu werden. Mit Herstellerlisten für die technische Ausrüstung! Geschrieben in erster Linie für die industrielle Praxis - weniger für akademische Forschung und Lehre.




Dispersing Powders in Liquids


Book Description

This book provides powder technologists with laboratory procedures for selecting dispersing agents and preparing stable dispersions that can then be used in particle size characterization instruments. Its broader goal is to introduce industrial chemists and engineers to the phenomena, terminology, physical principles, and chemical considerations involved in preparing and handling dispersions on a commercial scale. The book introduces novices to: - industrial problems due to improper degree of dispersion; - the nomenclature used in describing particles; - the basic physical phenomena, equations, and chemistry involved in particle interactions; - the analytical techniques used for evaluating solid-liquid interfaces - textbooks, courses, societies, and vendors that can provide an advanced understanding of dispersion phenomena. The book provides resources for more experienced technologists by: - discussing characteristics and applications of the various chemical classes of surfactants; - providing procedures for selecting and optimizing a dispersant for a specific solid-liquid system and end-use constraints; - naming typical commercial surfactants and listing the addresses and telephone numbers of their manufacturers; - illustrating the many physical and chemical equilibria that must be considered in modelling a dispersion and guiding the reader to the sources of both data and advanced theoretical treatments required to implement such models. The author has for several years been a consultant in the field of slurry technology, obtaining information, materials, equipment, and expert advice required to solve slurry problems. He also teaches slurry technology and powder dispersion courses to students who are either engineers recently graduated from college or managers recently transferred to plants that handle slurries. His expertise gives the book a wide appeal: as virtually every manufacturing process involves dispersions of powders in liquids, it is of interest to chemists and chemical engineers in industry; the concise definitions, descriptions and examples make it an ideal reference text for teachers and students.




Particle Size Measurement


Book Description

This is the fifth edition of the highly successful work first published in 1968, comprising two definitive volumes on particle characterisation. The first volume is devoted to sampling and particle size measurement, while surface area and pore size determination are reviewed in volume 2. Particle size and characterisation are central to understanding powder properties and behaviour. This book describes numerous potential measuring devices, how they operate and their advantages and disadvantages. It comprise a fully comprehensive treatise on the wide range of available equipment with an extensive literature survey, and a list of manufacturers and suppliers. The author's blend of academic and industrial experience results in a readable technical book with information on how to analyse, present, and extract useful information from data. This is an essential reference book for both industrial and academic research workers in a variety of areas including: pharmaceuticals, food science, pollution analysis and control, electronic materials, agricultural products, polymers, pigments and chemicals.




Particulate Interactions in Dry Powder Formulation for Inhalation


Book Description

Interactions between drug particulates are crucial in determining drug dispersion and deaggregation, and ultimately delivery efficiency. This book combines principles established in surface and colloidal chemistry with pharmaceutical powder technology. It discusses some of the factors affecting particulate interactions, and particle-fluid interaction in the respiratory tract. It review some of the studies carried out in dry powder formulation development, and proposes possible strategies in improving DPI efficiency. The majority of these principles are applicable to other pharmaceutical solid dosage forms (e.g. tablets and capsules).




Amorphous Solid Dispersions


Book Description

This volume offers a comprehensive guide on the theory and practice of amorphous solid dispersions (ASD) for handling challenges associated with poorly soluble drugs. In twenty-three inclusive chapters, the book examines thermodynamics and kinetics of the amorphous state and amorphous solid dispersions, ASD technologies, excipients for stabilizing amorphous solid dispersions such as polymers, and ASD manufacturing technologies, including spray drying, hot melt extrusion, fluid bed layering and solvent-controlled micro-precipitation technology (MBP). Each technology is illustrated by specific case studies. In addition, dedicated sections cover analytical tools and technologies for characterization of amorphous solid dispersions, the prediction of long-term stability, and the development of suitable dissolution methods and regulatory aspects. The book also highlights future technologies on the horizon, such as supercritical fluid processing, mesoporous silica, KinetiSol®, and the use of non-salt-forming organic acids and amino acids for the stabilization of amorphous systems. Amorphous Solid Dispersions: Theory and Practice is a valuable reference to pharmaceutical scientists interested in developing bioavailable and therapeutically effective formulations of poorly soluble molecules in order to advance these technologies and develop better medicines for the future.