Toxicology Cases for the Clinical and Forensic Laboratory


Book Description

Toxicology Cases for the Clinical and Forensic Laboratory brings together carefully selected case studies to teach important principles relating to drug and toxin exposures. Each case study includes contemporary clinical and forensic toxicologist studies that include a comprehensive analytical and clinical approach to patient management and address overdoses from designer drugs, to NSAIDS, to opioids, to stimulants. These cases present a comprehensive, analytical and clinical approach to managing a drug overdose. This is a must-have reference for clinical and forensic laboratory scientists, along with toxicology and pathology residents who need to know aspects of both. - Brings together expert cases encompassing analytical toxicology, clinical medicine and basic science in a consolidated format - Presents unique and challenging cases in clinical laboratories contributed by experts in the field - Consolidated format that make concepts in toxicology easy to learn and teach - Key learning points highlighted with multiple choice questions




Foye's Principles of Medicinal Chemistry


Book Description

With expert contributions from experienced educators, research scientists and clinicians, Foye’s Principles of Medicinal Chemistry, Eighth Edition is an invaluable resource for professional students, graduate students and pharmacy faculty alike. This ‘gold standard’ text explains the chemical basis of drug action, emphasizing the structure-activity relationships, physicochemical-pharmacokinetic properties, and metabolic profiles of the most commonly used drugs.




Karch's Drug Abuse Handbook


Book Description

Karch’s Drug Abuse Handbook, Third Edition remains the quintessential compendium addressing the pharmacological, medical, and legal aspects of drugs and informing the forensic community of the latest scientific advances and emergent practices. For this edition, Dr. Karch has brought on clinical and forensic toxicology expert Dr. Bruce Goldberger, editor-in-chief of the Journal of Analytical Toxicology and president of the American Board of Forensic Toxicology, to serve as co-editor. In addition, world-renowned scientists and medical professionals have contributed their work and expertise in tackling the latest developments in drug testing, drug-related medical emergencies, and the drug toxicology. Topics addressed include genetic testing in drug death investigation, pathology, toxicogenetics, alcohol, post-mortem toxicology, new psychoactive substances, the latest legal issues and challenges as well as drugs and drug testing in sports, and the ethical, legal, and practical issues involved. Vivid pictures and diagrams throughout illustrate the pathological effects of drugs and the chemical make-up and breakdown of abused drugs. With unparalleled detail, the latest research and the highest level of authoritative medical scientific information, The Drug Abuse Handbook, Third Edition remains the definitive resource for drug related issues.




Diagnostic Pathology: Forensic Autopsy E-Book


Book Description

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Specifically designed to assist hospital pathologists and assistants, forensic pathology fellows, pathology residents, and medical examiners, it provides a comprehensive, authoritative discussion of key topics in forensic autopsy. Richly illustrated and easy to use, Diagnostic Pathology: Forensic Autopsy is a one-stop reference on the performance of procedures in this challenging field, ideal as a day-to-day reference or as a reliable training resource. - Provides expert guidance on accurate diagnoses of the findings and patterns encountered in the forensic autopsy, as well as cause of death procedures - Covers key topics such as opioid and drug deaths, including new drugs and their toxicology; deaths and investigations in custody; infant and child deaths, including SIDS and overlaying; and infant and child neck trauma, including shaken baby syndrome - Contains the necessary information to aid in the performance of both routine and complicated forensic autopsies - Features hundreds of high-quality images throughout, including full-color illustrations and clinical and gross pathology photographs—all carefully annotated to highlight the most diagnostically significant factors - Features a templated, highly formatted design; concise, bulleted text; key facts in each chapter; and an extensive index for easy reference - Offers authoritative, readable coverage for those who need to learn and understand important aspects of forensic autopsy, including coroners, medico-legal death investigators, and legal investigators - Includes the enhanced eBook version, which allows you to search all text, figures, and references on a variety of devices




Information Resources in Toxicology, Volume 1: Background, Resources, and Tools


Book Description

This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology's subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools.Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology's presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field.The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving increased emphasis are disaster preparedness, nanotechnology, -omics, risk assessment, societal implications such as ethics and the precautionary principle, climate change, and children's environmental health. - Introductory chapters provide a backdrop to the science of toxicology, its history, the origin and status of toxicoinformatics, and starting points for identifying resources - Offers an extensive array of chapters organized by subject, each highlighting resources such as journals, databases,organizations, and review articles - Includes chapters with an emphasis on format such as government reports, general interest publications, blogs, and audiovisuals - Explores recent internet trends, web-based databases, and software tools in a section on the online environment - Concludes with a miscellany of special topics such as laws and regulations, chemical hazard communication resources, careers and professional education, K-12 resources, funding, poison control centers, and patents - Paired with Volume Two, which focuses on global resources, this set offers the most comprehensive compendium of print, digital, and organizational resources in the toxicological sciences with over 120 chapters contributions by experts and leaders in the field




Practical Forensic Pathology and Toxicology


Book Description

Practical Forensic Pathology and Toxicology is a companion to the authors’ original book on the subject, Forensic Toxicology: Mechanisms and Pathology. This new volume addresses issues that forensic pathologists face when confronted by the suspected or demonstrated presence of drugs or toxins in their cases. Since such considerations include the need for a basic understanding of the direct physiological effects of potentially toxic agents, the authors highlight various connections and interaction between forensic pathology and toxicology. The book is written for both the practicing pathologist, and those in training, who may already have some knowledge of forensic medicine but are on occasion faced with issues that reach beyond a basic determination of cause and manner of death. Pathologists are expected to provide informed, well‐reasoned opinions explaining how a person died—which includes questions about any drugs, prescription medications, or otherwise that may have caused or contributed to death. As such, this book looks at the direct physiological effects of drugs and toxins, answering questions such as “Why does hypernatremia cause seizures?” or “Why can synthetic cannabinoids cause fatal complications, yet THC does not?” or the very timely “What is the mechanism by which an opiate overdose causes death?” Coverage primarily centers on the pathological derangements and physiological consequences of the actions of drugs and toxins, and the cellular mechanisms by which those pathological consequences arise. Organized using an organ system approach, sections are divided into major target organ systems and sections included for affected organs and tissues. While some drugs affect more than one organ system—and some patients will have multiple drugs present—the book’s categorization and organization take this approach to be readily usable for the reader. Case reports are included with additional patient data to show the effects of specific toxins and poisons both alone and in combination with natural disease. Color figures illustrate all aspects of drug or toxin impact on postmortem casework including the scene of death, the deceased persons, and the organs and tissues affected. Practical Forensic Pathology and Toxicology is an invaluable resource for practicing pathologists, toxicologists, and those training for those fields. It also serves as a useful reference for lawyers, judges, insurance companies, and other medical professionals who need to know, in light of what drugs are present in a particular case, what such compounds do, and how their presence (or absence thereof) is—or is not—related to an individual’s death.




Handbook of Forensic Medicine


Book Description

Der Goldstandard unter den Referenzwerken der Rechtsmedizin In der zweiten Auflage des Handbook of Forensic Medicine vermittelt der Herausgeber Burkhard Madea der Leserschaft einen umfassenden, internationalen Ansatz in der Rechtsmedizin mithilfe eines Teams von Experten aus aller Welt. Das Buch enthält neue Inhalte zu den Themen Tatortuntersuchung, Analyse von Blutfleckenmustern, Terroranschläge, Brandkatastrophen, neue psychoaktive Substanzen und Molekularpathologie sowie einen umfassenden Überblick über sämtliche Aspekte der Rechtsmedizin. In den einzelnen Kapiteln werden alle Faktoren der Qualitätskontrolle und Best Practices behandelt. Anhand von Fallstudien werden die dort erläuterten Konzepte veranschaulicht und die Verbindungen zwischen verschiedenen Teildisziplinen hervorgehoben. Für Spezialisten, die täglich im Einsatz sind, werden in jedem Kapitel die Elemente der Routineanalyse behandelt. In der zweiten Auflage des Handbook of Forensic Medicine werden die neuesten Entwicklungen in der forensischen Molekularbiologie, der forensischen Toxikologie, der Molekularpathologie und der Immunhistochemie besprochen. Darüber hinaus bietet das Werk: * Eine gründliche Einführung in die Aufgaben der Rechtsmedizin in der modernen Gesellschaft mit einer Darstellung der internationalen Richtlinien und Akkreditierungen in der Rechtsmedizin * Umfassende Betrachtungen der medizinischen Aspekte des Todes, insbesondere des Wesens und der Definition von Tod, Autopsie und der Identifizierung der Opfer von Massenkatastrophen * Praktische Erörterungen zur Traumatologie und zum gewaltsamen Tod, insbesondere durch Ersticken, Stromschlag und Blitzschlag, Kindstötung und ärztliche Kunstfehler * Tiefgreifende Untersuchungen zum plötzlichen und unerwarteten Tod aus natürlichen Gründen, auch zur Biochemie nach dem Tod Dieses Buch ist unverzichtbar für jeden Experten in der Rechtsmedizin, Toxikologie und Hämogenetik sowie für alle, die Gutachten für Gerichtsverfahren erstellen sollen. Auch für Rechtsanwälte und Jurastudenten ist es ein ideales Nachschlagewerk.




Harwood-Nuss' Clinical Practice of Emergency Medicine


Book Description

Clinically focused and evidence-based, Harwood-Nuss’ Clinical Practice of Emergency Medicine, Seventh Edition, is a comprehensive, easy-to-use reference for practitioners and residents in today’s Emergency Department (ED). Templated chapters rapidly guide you to up to date information on clinical presentation, differential diagnosis, evaluation, management, and disposition, including highlighted critical interventions and common pitfalls. This concise text covers the full range of conditions you’re likely to see in the ED, with unmatched readability for quick study and reference.







Atlas of Forensic Pathology: A Pattern Based Approach


Book Description

Atlas of Forensic Pathology: A Pattern-Based Approach, by Dr. Walter L. Kemp (Montana State Medical Examiner), Dr. Rhome L. Hughes, and Dr. Jeffrey J. Barnard (Dallas County Chief Medical Examiner) provides a highly illustrated succinct “day-to-day” educational guide to the interpretation of patterns of findings at forensic autopsy to best allow for an accurate determination of cause and manner of death. The format of the book will also guide a pathologist in how to identify pertinent information (i.e., how to search for the patterns) and assemble a thorough and streamlined autopsy report.