E. Merck's Annual Report


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Beans, Roots and Leaves


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Parkinsonism of various types has long been a debilitating and cruel affliction for significant numbers of people, and even today the cure remains elusive. The present volume explores the colorful and sometimes alarming history of the attempts to provide at least some relief from the symptoms of this disorder, commencing with interesting reports from ancient India and medieval Europe and continuing until the present time. Especial attention is devoted to L-DOPA therapy, still the leading pharmacological approach to the disorder more than forty years after its first application, and its place in the development of neurochemistry. But the employment of solanaceous plant alkaloid-based therapies, which dominated antiparkinsonian therapy until the mid-20th century, and the broad range of other approaches which found varying degrees of popularity, including those stimulated by the encephalitis epidemic which appeared in Europe during the First World War, are also discussed. The author concludes that antiparkinsonian therapy was never 'irrational', but was rather always determined by prevailing medical, pharmacological and scientific paradigms, so that its history is inextricably linked with experimental and clinical developments in these fields.




The Endocrine Survey


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The Merck Report


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International Financial Reporting Standards


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International Financial Reporting Standards: A Framework-based Perspective links broad concepts and general accounting principles to the specific requirements of IFRS to help students develop and understand the judgments required in using a principle-based standard. Although it is still unclear whether the US will adopt IFRS, the global business environment makes it necessary for accounting students and professionals to be bilingual in both US GAAP and IFRS. This comprehensive textbook offers: A clear presentation of the concepts underlying IFRS A conceptual framework to guide students in interpreting and applying IFRS rules A comparison between IFRS and US GAAP to develop students’ understanding of the requirements of each standard Real world examples and case studies to link accounting theory to practice, while also exposing students to different interpretations and applications of IFRS End of chapter material covering other aspects of financial reporting, including international auditing standards, international ethics standards, and corporate governance and enforcement, as well as emerging topics, such as integrated accounting, sustainability and social responsibility accounting and new forms of financial reporting Burton & Jermakowicz have crafted a thorough and extensive tool to give students a competitive edge in understanding, and applying IFRS. A companion website provides additional support for both students and instructors.