Uncertainty Quantification in Computational Fluid Dynamics


Book Description

Fluid flows are characterized by uncertain inputs such as random initial data, material and flux coefficients, and boundary conditions. The current volume addresses the pertinent issue of efficiently computing the flow uncertainty, given this initial randomness. It collects seven original review articles that cover improved versions of the Monte Carlo method (the so-called multi-level Monte Carlo method (MLMC)), moment-based stochastic Galerkin methods and modified versions of the stochastic collocation methods that use adaptive stencil selection of the ENO-WENO type in both physical and stochastic space. The methods are also complemented by concrete applications such as flows around aerofoils and rockets, problems of aeroelasticity (fluid-structure interactions), and shallow water flows for propagating water waves. The wealth of numerical examples provide evidence on the suitability of each proposed method as well as comparisons of different approaches.




Digital Filters and Signal Processing


Book Description

Digital filters, together with signal processing, are being employed in the new technologies and information systems, and are implemented in different areas and applications. Digital filters and signal processing are used with no costs and they can be adapted to different cases with great flexibility and reliability. This book presents advanced developments in digital filters and signal process methods covering different cases studies. They present the main essence of the subject, with the principal approaches to the most recent mathematical models that are being employed worldwide.




Optimization and Computational Fluid Dynamics


Book Description

The numerical optimization of practical applications has been an issue of major importance for the last 10 years. It allows us to explore reliable non-trivial configurations, differing widely from all known solutions. The purpose of this book is to introduce the state-of-the-art concerning this issue and many complementary applications are presented.




Cardiovascular Biomechanics


Book Description

This book provides a balanced presentation of the fundamental principles of cardiovascular biomechanics research, as well as its valuable clinical applications. Pursuing an integrated approach at the interface of the life sciences, physics and engineering, it also includes extensive images to explain the concepts discussed. With a focus on explaining the underlying principles, this book examines the physiology and mechanics of circulation, mechanobiology and the biomechanics of different components of the cardiovascular system, in-vivo techniques, in-vitro techniques, and the medical applications of this research. Written for undergraduate and postgraduate students and including sample problems at the end of each chapter, this interdisciplinary text provides an essential introduction to the topic. It is also an ideal reference text for researchers and clinical practitioners, and will benefit a wide range of students and researchers including engineers, physicists, biologists and clinicians who are interested in the area of cardiovascular biomechanics.




Fluid-Structure Interaction


Book Description

This volume in the series Lecture Notes in Computational Science and Engineering presents a collection of papers presented at the International Workshop on FSI, held in October 2005 in Hohenwart and organized by DFG's Research Unit 493 "FSI: Modeling, Simulation, and Optimization". The papers address partitioned and monolithic coupling approaches, methodical issues and applications, and discuss FSI from the mathematical, informatics, and engineering points of view.




TEXTBOOK OF COMPUTER AIDED DRUG DEVELOPMENT


Book Description

This book explores the use of computer-assisted techniques in the discovery, design, optimization, and production of innovative pharmaceutical formulations and drug delivery systems, with an emphasis on their effectiveness and safety. It discusses computational methods, statistical and molecular modeling, all aimed at advancing the development and safe administration of drugs in humans. The book thoroughly examines the integration of Quality by Design (QbD), Design of Experiments (DoE), artificial intelligence, and in silico pharmacokinetic assessment/simulation, facilitated by commercial software and expert systems, and includes examples from recent research. "Computer-aided Pharmaceutics and Drug Delivery" serves as a comprehensive reference for the latest scholarly updates on emerging developments in computer-assisted techniques for drug design and development. It is intended for pharmacists, medical practitioners, students, and researchers seeking authoritative insights into this evolving field.




Cardiovascular Mechanics


Book Description

The objective of this book is to illustrate in specific detail how cardiovascular mechanics stands as a common pillar supporting such different clinical successes as drugs for high blood pressure, prosthetic heart valves and coronary artery bypass grafting, among others. This information is conveyed through a comprehensive treatment of the overarching principles and theories that are behind mechanobiological processes, aortic and arterial mechanics, atherosclerosis, blood and microcirculation, hear valve mechanics, as well as medical devices and drugs. Examines all major theoretical and practical aspects of mechanical forces related to the cardiovascular system. Discusses a unique coverage of mechanical changes related to an aging cardiovascular system. Provides an overview of experimental methods in cardiovascular mechanics. Written by world-class researchers from Canada, the US and EU. Extensive references are provided at the end of each chapter to enhance further study. Michel R. Labrosse is the founder of the Cardiovascular Mechanics Laboratory at the University of Ottawa, where he is a full professor within the Department of Mechanical Engineering. He has been an active researcher in academia along with being heavily associated with the University of Ottawa Heart Institute. He has authored or co-authored over 90 refereed communications, and supervised or co-supervised over 40 graduate students and post-docs.




Computational Methods for Solids and Fluids


Book Description

This volume contains the best papers presented at the 2nd ECCOMAS International Conference on Multiscale Computations for Solids and Fluids, held June 10-12, 2015. Topics dealt with include multiscale strategy for efficient development of scientific software for large-scale computations, coupled probability-nonlinear-mechanics problems and solution methods, and modern mathematical and computational setting for multi-phase flows and fluid-structure interaction. The papers consist of contributions by six experts who taught short courses prior to the conference, along with several selected articles from other participants dealing with complementary issues, covering both solid mechanics and applied mathematics.




AIAA Guide for the Verification and Validation of Computational Fluid Dynamics Simulations


Book Description

This document defines a number of key terms, discusses fundamental concepts, and specifies general procedures for conducting verification and validation of computational fluid dynamics simulations. It's goal is to provide a foundation for the major issues and concepts in verification and validation. However, it does not recommend standards in these areas because a number of important issues are not yet resolved.




Data Streams


Book Description

In the data stream scenario, input arrives very rapidly and there is limited memory to store the input. Algorithms have to work with one or few passes over the data, space less than linear in the input size or time significantly less than the input size. In the past few years, a new theory has emerged for reasoning about algorithms that work within these constraints on space, time, and number of passes. Some of the methods rely on metric embeddings, pseudo-random computations, sparse approximation theory and communication complexity. The applications for this scenario include IP network traffic analysis, mining text message streams and processing massive data sets in general. Researchers in Theoretical Computer Science, Databases, IP Networking and Computer Systems are working on the data stream challenges.