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Elements of Mammalian Fertilization

Author : Paul M. Wassarman

Publisher : CRC Press

Page : 198 pages

File Size : 24,44 MB

Release : 1990-11-26

Category : Medical

ISBN : 9780849363870

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Book Description

Elements of Mammalian Fertilization, Volume 2 discusses in vitro fertilization (IVF) in humans and domestic animals and provides insight into potential applications of contemporary experimental approaches to contraceptive development. Topics covered include the origins and history of human IVF, technical considerations and diverse factors that often determine the success or failure of human IVF, the application of IVF to domestic animals, and the application of gamete biochemistry and molecular biology toward development of novel methods of contraception. This volume addresses some of the most exciting technological developments that have occurred over the past decade, developments that have already dramatically affected our lives and will continue to do so in the future. It is an important reference source for research scientists, clinicians, and advanced graduate and medical students.





Mammalian Development

Author : Patrick P. L. Tam

Publisher :

Page : 0 pages

File Size : 37,12 MB

Release : 2013

Category : Science

ISBN : 9781936113248

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Book Description

"A subject collection from Cold Spring Harbor perspectives in biology."



Sexual Reproduction in Animals and Plants

Author : Hitoshi Sawada

Publisher : Springer

Page : 463 pages

File Size : 18,22 MB

Release : 2014-02-07

Category : Science

ISBN : 4431545891

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Book Description

This book contains the proceedings of the International Symposium on the Mechanisms of Sexual Reproduction in Animals and Plants, where many plant and animal reproductive biologists gathered to discuss their recent progress in investigating the shared mechanisms and factors involved in sexual reproduction. This now is the first book that reviews recent progress in almost all fields of plant and animal fertilization. It was recently reported that the self-sterile mechanism of a hermaphroditic marine invertebrate (ascidian) is very similar to the self-incompatibility system in flowering plants. It was also found that a male factor expressed in the sperm cells of flowering plants is involved in gamete fusion not only of plants but also of animals and parasites. These discoveries have led to the consideration that the core mechanisms or factors involved in sexual reproduction may be shared by animals, plants and unicellular organisms. This valuable book is highly useful for reproductive biologists as well as for biological scientists outside this field in understanding the current progress of reproductive biology.



Textbook of Clinical Embryology

Author : Kevin Coward

Publisher : Cambridge University Press

Page : 408 pages

File Size : 25,37 MB

Release : 2013-10-31

Category : Medical

ISBN : 110727625X

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Book Description

The success of Assisted Reproductive Technology is critically dependent upon the use of well optimized protocols, based upon sound scientific reasoning, empirical observations and evidence of clinical efficacy. Recently, the treatment of infertility has experienced a revolution, with the routine adoption of increasingly specialized molecular biological techniques and advanced methods for the manipulation of gametes and embryos. This textbook – inspired by the postgraduate degree program at the University of Oxford – guides students through the multidisciplinary syllabus essential to ART laboratory practice, from basic culture techniques and micromanipulation to laboratory management and quality assurance, and from endocrinology to molecular biology and research methods. Written for all levels of IVF practitioners, reproductive biologists and technologists involved in human reproductive science, it can be used as a reference manual for all IVF labs and as a textbook by undergraduates, advanced students, scientists and professionals involved in gamete, embryo or stem cell biology.



Maternal Control of Development in Vertebrates

Author : Florence Louise Marlow

Publisher : Morgan & Claypool Publishers

Page : 221 pages

File Size : 26,4 MB

Release : 2010

Category : Family & Relationships

ISBN : 161504051X

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Book Description

Eggs of all animals contain mRNAs and proteins that are supplied to or deposited in the egg as it develops during oogenesis. These maternal gene products regulate all aspects of oocyte development, and an embryo fully relies on these maternal gene products for all aspects of its early development, including fertilization, transitions between meiotic and mitotic cell cycles, and activation of its own genome. Given the diverse processes required to produce a developmentally competent egg and embryo, it is not surprising that maternal gene products are not only essential for normal embryonic development but also for fertility. This review provides an overview of fundamental aspects of oocyte and early embryonic development and the interference and genetic approaches that have provided access to maternally regulated aspects of vertebrate development. Some of the pathways and molecules highlighted in this review, in particular, Bmps, Wnts, small GTPases, cytoskeletal components, and cell cycle regulators, are well known and are essential regulators of multiple aspects of animal development, including oogenesis, early embryogenesis, organogenesis, and reproductive fitness of the adult animal. Specific examples of developmental processes under maternal control and the essential proteins will be explored in each chapter, and where known conserved aspects or divergent roles for these maternal regulators of early vertebrate development will be discussed throughout this review. Table of Contents: Introduction / Oogenesis: From Germline Stem Cells to Germline Cysts / Oocyte Polarity and the Embryonic Axes: The Balbiani Body, an Ancient Oocyte Asymmetry / Preparing Developmentally Competent Eggs / Egg Activation / Blocking Polyspermy / Cleavage/ Mitosis: Going Multicellular / Maternal-Zygotic Transition / Reprogramming: Epigenetic Modifications and Zygotic Genome Activation / Dorsal-Ventral Axis Formation before Zygotic Genome Activation in Zebrafish and Frogs / Maternal TGF-β and the Dorsal-Ventral Embryonic Axis / Maternal Control After Zygotic Genome Activation / Compensation by Stable Maternal Proteins / Maternal Contributions to Germline Establishment or Maintenance / Perspective / Acknowledgments / References



Biology and Pathology of the Oocyte

Author : Alan Trounson

Publisher : Cambridge University Press

Page : 464 pages

File Size : 21,56 MB

Release : 2013-10-24

Category : Medical

ISBN : 1107470293

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Book Description

The human egg - the rarest and most rapidly aging cell in the body - is a topic of intense scientific study. Assisted reproduction clinics are constantly vying to improve success rates - choosing the best gametes is a key step in this process. This new edition of what one reviewer of the first edition described as 'possibly the definitive work on the oocyte' covers the development, biology and pathology of the oocyte, and technologies to manipulate, enhance and control fertility. These technologies are used to overcome infertility, avoid inherited diseases, and create genetically engineered embryos from stem cells and cloning. This progress would have been impossible without the myriad of scientific and technical developments covered in this book. The new edition is thoroughly updated and includes major new research on reprogramming, oocyte molecular development, cryopreservation and viability. We are in exciting times for the egg.





A Comparative Overview of Mammalian Fertilization

Author : Bonnie S. Dunbar

Publisher : Springer Science & Business Media

Page : 458 pages

File Size : 23,72 MB

Release : 2013-06-29

Category : Science

ISBN : 1475789823

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Book Description

In 1964, the Fertilization and Gamete Physiology Research Training Program (FERGAP) was established at the Marine Biological Laboratories, Woods Hole, Massachusetts. Over the course of the next 12 years, under the directorship of Dr. Charles B. Metz, FERGAP brought together, trained, and inspired a generation of students in reproductive biology from all over the world. As students of C. B. Metz and as FERGAP trainees, we would like to dedicate this collected work on comparative mammalian fertilization to our teacher and mentor, Dr. Charles B. Metz. Like a number of authors contributing to this volume, we have been struck by the significant impact that C. B. Metz and FERGAP had on the development of students of reproductive biology. Applying both the classical and molecular techniques of cell biology and immunology to problems of gamete biology, Dr. Metz emphasized a comparative and analytical approach that was reflected in his own research on fertilization in Paramecia, sea urchins, frogs, and mammals. It is hoped that this volume will serve to stimulate students to discover the myriad of fascinating research problems in gamete and reproductive biology. Bonnie S. Dunbar Michael G. O'Rand Houston, Texas Chapel Hill, North Carolina ix Contents Part I COMPARATIVE OVERVIEW OF MAMMALIAN GAMETES The Coevolution of Mammalian Gametes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 J. Michael Bedford I. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2. Gamete Design . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 2.1. Monotremes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 . . . . . . . . . . . . . . 2.2. Marsupials . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 . . . . . . . . . . . . . . . 2.3. Eutherians . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 3. Gamete Maturation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 . . . . . . . . . . . . . . . 3 .1. Oocyte Maturation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 . . . . . . . . . . . . . 3.2. Sperm Maturation in the Male . . . . . . . . . . . . . . . . . . . . . . . 15 . . . . . . . . . .



The Sperm Cell

Author : Christopher J. De Jonge

Publisher : Cambridge University Press

Page : 372 pages

File Size : 15,60 MB

Release : 2006-04-06

Category : Medical

ISBN : 9780521853972

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Book Description

Originally published in 2006, this is a comprehensive and definitive account of the human male gamete. The volume summarizes many unique and revealing characteristics of the sperm cell. It provides a detailed overview of human sperm production, maturation and function, and looks at how these processes affect and influence fertility, infertility and ART. The volume thus provides a detailed review of the most important research and developments, augmented with pertinent references. This book will appeal to all practitioners and scientists in reproductive medicine and in particular to clinical scientists, graduate and post-graduate scientists, and laboratory personnel.