Author : Kozo Shinoda
Publisher : Wiley-Interscience
Page : 208 pages
File Size : 34,17 MB
Release : 1986-08-21
Category : Science
ISBN :
Contains information useful for demonstrating the relation between the function of Hydrophilic Lipophilic Balance (HLB) and solubilization, microemulsions and emulsion stability or inversion. Covers the effect of temperature on systems containing nonionic surfactants and studies of the surfactant as a function of temperature. Also demonstrates how the HLB solution properties of the surfactant can be controlled to change from water-soluble to oil-soluble.
Author : K.L. Mittal
Publisher : Springer Science & Business Media
Page : 460 pages
File Size : 29,79 MB
Release : 2012-12-06
Category : Science
ISBN : 1461341574
This volume and its companion Volume 1 chronicle the proceed ings of the International Symposium on Micellization, Solubiliza tion, and tficroemulsions held under the auspices of the Northeast Regional Meeting of the American Chemical Society in Albany, New York, August 8-11, 1976. The technical program consisted of 48 papers by 91 authors from twelve countries. The program was divided into six sessions, and Dr. Hartley delivered the Concluding Remarks. Subsequently, six more papers were contributed for the proceedings volumes with the result that these volumes contain Sl papers (three papers are not included for certain reasons) and are divided into seven parts. The first three parts are embodied in Volume I and the remaining four parts constitute Volume 2; each part is followed by a Discussion Section. Dr. Hartley's Concluding Remarks are in cluded in both volumes. When the idea of arranging a symposium on micelles was broached to me, I accepted it without an iota of hesitation. I had two op tions: either to make it a one- or two-sessions symposium, or bring together the global community actively carrying out research in this area. I opted for the latter as the subject was very timely and I knew that it would elicit very enthusiastic response. In order to broaden the scope of the symposium, I suggested that the theme of the symposium should be Micellizationy Solubilization and Microemulsions.
Author : Rainer H. Müller
Publisher : CRC Press
Page : 410 pages
File Size : 20,65 MB
Release : 1998
Category : Business & Economics
ISBN : 9783887630690
Explore possible new approaches for overcoming poorly soluble drugs - a challenge to drug formulation work and an increasing problem. Many newly developed drugs are poorly soluble, very often simultaneously in aqueous and in organic media. Emulsions and Nanosuspensions for the Formulation of Poorly Soluble Drugs aims to: review the possibilities, limitations and future perspectives of emulsions as drug carriers considering technology from other than the phamaceutical industry (i.e food industry). show the production technology of nanosuspensions, explain the special dissolution properties (i.e. increased saturation solubility) and increased dissolution velocity (theory), and cover the possible applications. present the theory of high pressure homogenization and high pressure extrusion in dispersion techniques, including examples of applications and size measurements in concentrated dispersions.
Author : Tharwat F. Tadros
Publisher : John Wiley & Sons
Page : 283 pages
File Size : 20,92 MB
Release : 2013-06-04
Category : Science
ISBN : 3527647961
The importance of emulsification techniques, their use in the production of nanoparticles for biomedical applications as well as application of rheological techniques for studying the interaction between the emulsion droplets is gathered in this reference work. Written by some of the top scientists within their respective fields, this book covers such topics as emulsions, nano-emulsions, nano-dispersions and novel techniques for their investigation. It also considers the fundamental approach in areas such as controlled release, drug delivery and various applications of nanotechnology.
Author : Seid Mahdi Jafari
Publisher : Academic Press
Page : 665 pages
File Size : 32,33 MB
Release : 2018-02-24
Category : Technology & Engineering
ISBN : 0128118393
Nanoemulsions: Formulation, Applications, and Characterization provides detailed information on the production, application and characterization of food nanoemulsion as presented by experts who share a wealth of experience. Those involved in the nutraceutical, pharmaceutical and cosmetic industries will find this a useful reference as it addresses findings related to different preparation and formulation methods of nanoemulsions and their application in different fields and products. As the last decade has seen a major shift from conventional emulsification processes towards nanoemulsions that both increase the efficiency and stability of emulsions and improve targeted drug and nutraceutical delivery, this book is a timely resource. - Summarizes general aspects of food nanoemulsions and their formulation - Provides detailed information on the production, application, and characterization of food nanoemulsion - Reveals the potential of nanoemulsions, as well as their novel applications in functional foods, nutraceutical products, delivery systems, and cosmetic formulations - Explains preparation of nanoemulsions by both low- and high-energy methods
Author : Sherril D. Christian
Publisher : CRC Press
Page : 568 pages
File Size : 33,1 MB
Release : 1995-04-10
Category : Science
ISBN : 9780824790998
This work covers topics ranging from fundamental studies of solubilization to practical technological applications of the phenomenon. It reviews the solubilization of organic materials into surfactant aggregates, including micelles, vesicles and admicelles. The book also details methods of measuring solubilization that utilize both classical and newer instrumental techniques. It is intended for physical, surface, colloid and surfactant chemists; chemical, environmental and civil engineers; and upper-level undergraduate and graduate students in these disciplines.
Author : David B. Troy
Publisher : Lippincott Williams & Wilkins
Page : 2452 pages
File Size : 21,66 MB
Release : 2006
Category : Medical
ISBN : 9780781746731
For over 100 years, Remington has been the definitive textbook and reference on the science and practice of pharmacy. This Twenty-First Edition keeps pace with recent changes in the pharmacy curriculum and professional pharmacy practice. More than 95 new contributors and 5 new section editors provide fresh perspectives on the field. New chapters include pharmacogenomics, application of ethical principles to practice dilemmas, technology and automation, professional communication, medication errors, re-engineering pharmacy practice, management of special risk medicines, specialization in pharmacy practice, disease state management, emergency patient care, and wound care. Purchasers of this textbook are entitled to a new, fully indexed Bonus CD-ROM, affording instant access to the full content of Remington in a convenient and portable format.
Author : Ron Liu
Publisher : CRC Press
Page : 781 pages
File Size : 49,35 MB
Release : 2018-03-12
Category : Medical
ISBN : 1351646826
Properties and Formulation: From Theory to Real-World Application Scientists have attributed more than 40 percent of the failures in new drug development to poor biopharmaceutical properties, particularly water insolubility. Issues surrounding water insolubility can postpone or completely derail important new drug development. Even the much-needed reformulation of currently marketed products can be significantly affected by these challenges. More recently it was reported that the percentage increased to 90% for the candidates of new chemical entities in the discovery stage and 75% for compounds under development. In the most comprehensive resource on the topic, this third edition of Water-Insoluble Drug Formulation brings together a distinguished team of experts to provide the scientific background and step-by-step guidance needed to deal with solubility issues in drug development. Twenty-three chapters systematically describe the detailed discussion on solubility theories, solubility prediction models, the aspects of preformulation, biopharmaceutics, pharmacokinetics, regulatory, and discovery support of water-insoluble drugs to various techniques used in developing delivery systems for water-insoluble drugs. This book includes more than 15 water-insoluble drug delivery systems or technologies, illustrated with case studies and featuring oral and parenteral applications. Highlighting the most current information and data available, this seminal volume reflects the significant progress that has been made in nearly all aspects of this field. The aim of this book is to provide a handy reference for pharmaceutical scientists in the handling of formulation issues related to water-insoluble drugs. In addition, this book may be useful to pharmacy and chemistry undergraduate students and pharmaceutical and biopharmaceutical graduate students to enhance their knowledge in the techniques of drug solubilization and dissolution enhancement.
Author : Conxita Solans
Publisher : CRC Press
Page : 424 pages
File Size : 47,88 MB
Release : 1996-11-27
Category : Science
ISBN : 9780824797959
"Fills a void in the literature by presenting the basic concepts of microemulsions, essential to understanding their industrial significance, and comprehensive descriptions of the most useful commerical applications. Discusses important issues related to enzymatic reactions and nanoparticle formation. Charts the enormous advances that have occurred in the field over the past decade."
Author : Martin J. Schick
Publisher : CRC Press
Page : 1166 pages
File Size : 19,89 MB
Release : 1987-03-27
Category : Science
ISBN : 9780824775308
