Reviews in Cell Biology and Molecular Medicine


Book Description

"This series is a classic..." - Molecular Medicine Today/Trends in Molecular Medicine The second edition of this highly acclaimed, sixteen-volume Encyclopedia now contains 150 new articles and extended coverage of cell biology. It is thus the most comprehensive and most detailed treatment of molecular biology, cell biology and molecular medicine available today -- designed in collaboration with a founding board of 10 Nobel laureates. As such, the Encyclopedia provides a single-source library of the molecular basis of life, with a focus on molecular medicine, discussing in detail the latest advances of the post-genomic era. Each of the approximately 425 articles is written as a self-contained treatment, beginning with an outline and a key word section plus definitions. Peer-reviewed, they are written in a review-like style, complemented by an extensive bipartite bibliography of reviews and books as well as primary papers. A glossary of basic terms completes each volume and defines the most commonly used terms in molecular biology. Together with the introductory illustrations found in each volume, the articles are comprehensible for readers at every level without resorting to a dictionary, textbook, or other reference. Praise for the first edition: "...an authoritative reference source of the highest quality. ... It is extremely well written and well illustrated..." - American Reference Books Annual (Library & Information Science Annual) "This series can be recommended without hesitation to a broad readership including students and qualified researchers... . ...articles...set-up facilitates easy reading and rapid understanding. ...overwhelming amount of valuable data." - Molecular Biology Reports ".. highly valuable and recommendable both for libraries and for laboratory use." - FEBS Letters




Reviews in Cell Biology and Molecular Medicine


Book Description

"This series is a classic..." - Molecular Medicine Today/Trends in Molecular Medicine The second edition of this highly acclaimed, sixteen-volume Encyclopedia now contains 150 new articles and extended coverage of cell biology. It is thus the most comprehensive and most detailed treatment of molecular biology, cell biology and molecular medicine available today -- designed in collaboration with a founding board of 10 Nobel laureates. As such, the Encyclopedia provides a single-source library of the molecular basis of life, with a focus on molecular medicine, discussing in detail the latest advances of the post-genomic era. Each of the approximately 425 articles is written as a self-contained treatment, beginning with an outline and a key word section plus definitions. Peer-reviewed, they are written in a review-like style, complemented by an extensive bipartite bibliography of reviews and books as well as primary papers. A glossary of basic terms completes each volume and defines the most commonly used terms in molecular biology. Together with the introductory illustrations found in each volume, the articles are comprehensible for readers at every level without resorting to a dictionary, textbook, or other reference. Praise for the first edition: "...an authoritative reference source of the highest quality. ... It is extremely well written and well illustrated..." - American Reference Books Annual (Library & Information Science Annual) "This series can be recommended without hesitation to a broad readership including students and qualified researchers... . ...articles...set-up facilitates easy reading and rapid understanding. ...overwhelming amount of valuable data." - Molecular Biology Reports ".. highly valuable and recommendable both for libraries and for laboratory use." - FEBS Letters




Guide to Reference in Medicine and Health


Book Description

Drawn from the extensive database of Guide to Reference, this up-to-date resource provides an annotated list of print and electronic biomedical and health-related reference sources, including internet resources and digital image collections.




Electrical Interactions in Molecular Biophysics


Book Description

Electrical Interactions in Molecular Biophysics: An Introduction deals with electrical interactions between biomolecules and therefore encompasses two disciplines, molecular biology and physics. The emphasis is on the electrical nature of biochemical or molecular biological reactions. The principles of electrostatics are used to explain some of the basic units of structure on a molecular level. Comprised of nine chapters, this book opens with an overview of the concepts and structures of biochemistry, with particular reference to different structural biochemical groups and how they are used as building blocks in forming molecules. The following chapters discuss the basics of elementary electrostatics; dielectric constants and dipoles; the dipole moments of biomolecules; van der Waals forces; and Debye-Huckel theory. Water and water structure are also considered from a physical standpoint. The final chapter is devoted to experimental techniques that rely upon the electrical properties of biomolecules and explains what types of information can be obtained from each experimental form. This monograph will be of interest to students and practitioners in biochemistry, molecular biology, biophysics, or microbiology.




Molecular Biophysics for the Life Sciences


Book Description

This volume provides an overview of the development and scope of molecular biophysics and in-depth discussions of the major experimental methods that enable biological macromolecules to be studied at atomic resolution. It also reviews the physical chemical concepts that are needed to interpret the experimental results and to understand how the structure, dynamics, and physical properties of biological macromolecules enable them to perform their biological functions. Reviews of research on three disparate biomolecular machines—DNA helicases, ATP synthases, and myosin--illustrate how the combination of theory and experiment leads to new insights and new questions.







Physics of Bio-Molecules and Cells


Book Description

Aimed at those working to enter this rapidly developing field, this volume on biological physics is written in a pedagogical style by leading scientists giving explanations that take their starting point where any physicist can follow and end at the frontier of research in biological physics. These lectures describe the state-of-the-art physics of biomolecules and cells. In biological systems ranging from single biomolecules to entire cells and larger biological systems, it focuses on aspects that require concepts and methods from physics for their analysis and understanding, such as the mechanics of motor proteins; how the genetic code is physically read and managed; the machinery of protein--DNA interactions; force spectroscopy of biomolecules' velopes, cytoskeletons, and cytoplasms; polymerization forces; listeria propulsion; cell motility; lab-on-a-chip nanotechnology for single-molecule analysis of biomolecules; bioinformatics; and coding and computational strategies of the brain.




Handbook of Single-Molecule Biophysics


Book Description

This handbook describes experimental techniques to monitor and manipulate individual biomolecules, including fluorescence detection, atomic force microscopy, and optical and magnetic trapping. It includes single-molecule studies of physical properties of biomolecules such as folding, polymer physics of protein and DNA, enzymology and biochemistry, single molecules in the membrane, and single-molecule techniques in living cells.




Biomolecular Interfaces


Book Description

The book focuses on the aqueous interface of biomolecules, a vital yet overlooked area of biophysical research. Most biological phenomena cannot be fully understood at the molecular level without considering interfacial behavior. The author presents conceptual advances in molecular biophysics that herald the advent of a new discipline, epistructural biology, centered on the interactions of water and bio molecular structures across the interface. The author introduces powerful theoretical and computational resources in order to address fundamental topics such as protein folding, the physico-chemical basis of enzyme catalysis and protein associations. On the basis of this information, a multi-disciplinary approach is used to engineer therapeutic drugs and to allow substantive advances in targeted molecular medicine. This book will be of interest to scientists, students and practitioners in the fields of chemistry, biophysics and biomedical engineering.