Author : W. J. Minkowycz
Publisher : CRC Press
Page : 398 pages
File Size : 46,22 MB
Release : 2009-03-27
Category : Medical
ISBN : 1420095226
Definitive Treatment of the Numerical Simulation of Bioheat Transfer and Fluid FlowMotivated by the upwelling of current interest in subjects critical to human health, Advances in Numerical Heat Transfer, Volume 3 presents the latest information on bioheat and biofluid flow. Like its predecessors, this volume assembles a team of renowned internatio
Author : Eric M. Brey
Publisher : CRC Press
Page : 402 pages
File Size : 48,63 MB
Release : 2014-08-07
Category : Medical
ISBN : 1466580453
A Complex and Growing Field The study of vascularization in tissue engineering and regenerative medicine (TERM) and its applications is an emerging field that could revolutionize medical approaches for organ and tissue replacement, reconstruction, and regeneration. Designed specifically for researchers in TERM fields, Vascularization: Regenerative Medicine and Tissue Engineering provides a broad overview of vascularization in TERM applications. This text summarizes research in several areas, and includes contributions from leading experts in the field. It defines the difficulties associated with multicellular processes in vascularization and cell-source issues. It presents advanced biomaterial design strategies for control of vascular network formation and in silico models designed to provide insight not possible in experimental systems. It also examines imaging methods that are critical to understanding vascularization in engineered tissues, and addresses vascularization issues within the context of specific tissue applications. This text is divided into three parts; the first section focuses on the basics of vascularization. The second section provides general approaches for promoting vascularization. The final section presents tissue and organ-specific aspects of vascularization in regenerative medicine. Presents Areas of Substantial Clinical and Societal Impact The material contains research and science on the process of vessel assembly with an emphasis on methods for controlling the process for therapeutic applications. It describes the tissue and organ-specific aspects of vascularization in regenerative medicine, and refers to areas such as bone tissue engineering, vascularization of encapsulated cells, adipose tissue, bone and muscle engineering. It also provides a mechanistic understanding of the process and presentation of experimental and computational approaches that facilitate the study of vascular assembly, and includes enabling technologies such as nanotechnology, drug delivery, stem cells, microfluidics, and biomaterial design that are optimized for supporting the formation of extensive vascular networks in regenerative medicine. A guide for researchers developing new methods for modulating vessel assembly, this text can also be used by senior undergraduate and graduate students taking courses focused on TERM.
Author : Murat Guvendiren
Publisher : MDPI
Page : 166 pages
File Size : 33,73 MB
Release : 2020-12-02
Category : Technology & Engineering
ISBN : 3039361120
Three-dimensional (3D) printing enables the fabrication of tissue-engineered constructs and devices from a patient’s own medical data, leading to the creation of anatomically matched and patient-specific constructs. There is a growing interest in applying 3D printing technologies in the fields of tissue engineering and regenerative medicine. The main printing methods include extrusion-based, vat photopolymerization, droplet-based, and powder-based printing. A variety of materials have been used for printing, from metal alloys and ceramics to polymers and elastomers as well as from hydrogels to extracellular matrix proteins. More recently, bioprinting, a subcategory of 3D printing, has enabled the precise assembly of cell-laden biomaterials (i.e., bioinks) for the construction of complex 3D functional living tissues or artificial organs. In this Special Issue, we aim to capture state-of-the-art research papers and the most current review papers focusing on 3D printing for tissue engineering and regenerative medicine. In particular, we seek novel studies on the development of 3D printing and bioprinting approaches, developing printable materials (inks and bioinks), and utilizing 3D-printed scaffolds for tissue engineering and regenerative medicine applications. These applications are not limited to but include scaffolds for in vivo tissue regeneration and tissue analogues for in vitro disease modeling and/or drug screening.
Author : Yong He
Publisher : John Wiley & Sons
Page : 370 pages
File Size : 45,59 MB
Release : 2022-03-14
Category : Technology & Engineering
ISBN : 3527347968
Provides an up-to-date outline of cell assembly methods and applications of 3D bioprinting Cell Assembly with 3D Bioprinting provides an accesible overview of the layer-by-layer manufacturing of living structures using biomaterials. Focusing on technical implemention in medical and bioengineering applications, this practical guide summarize each key aspect of the 3D bioprinting process. Contributions from a team of leading researchers describe bioink preparation, printing method selection, experimental protocols, integration with specific applications, and more. Detailed, highly illustrated chapters cover different bioprinting approaches and their applications, including coaxial bioprinting, digital light projection, direct ink writing, liquid support bath-assisted 3D printing, and microgel-, microfiber-, and microfluidics-based biofabrication. The book includes practical examples of 3D bioprinting, a protocol for typical 3D bioprinting, and relevant experimental data drawn from recent research. * Highlights the interdisciplinary nature of 3D bioprinting and its applications in biology, medicine, and pharmaceutical science * Summarizes a variety of commonly used 3D bioprinting methods * Describes the design and preparation of various types of bioinks * Discusses applications of 3D bioprinting such as organ development, toxicological research, clinical transplantation, and tissue repair Covering a wide range of topics, Cell Assembly with 3D Bioprinting is essential reading for advanced students, academic researchers, and industry professionals in fields including biomedicine, tissue engineering, bioengineering, drug development, pharmacology, bioglogical screening, and mechanical engineering.
Author : Ali Khademhosseini
Publisher : Artech House
Page : 647 pages
File Size : 22,16 MB
Release : 2008
Category : Science
ISBN : 1596931493
Supported with 140 illustrations, the volume exhaustively covers the micro- and nano-system technologies involved in developing cell-based bioengineering applications. You get full details on efforts to engineer the soluble and insoluble cell microenvironments, including the latest advances in microfluidic devices, surface patterning, 3D scaffolds, and techniques for engineering cellular mechanical properties and topography.
Author : Tatsuo Arai
Publisher : Springer
Page : 348 pages
File Size : 44,37 MB
Release : 2015-07-14
Category : Technology & Engineering
ISBN : 4431552979
Hyper Bio Assembler for Cellular Systems is the first book to present a new methodology for measuring and separating target cells at high speed and constructing 3D cellular systems in vitro. This book represents a valuable resource for biologists, biophysicists and robotic engineers, as well as researchers interested in this new frontier area, offering a better understanding of the measurement, separation, assembly, analysis and synthesis of complex biological tissue, and of the medical applications of these technologies. This book is the outcome of the new academic fields of the Ministry of Education, Culture, Sports, Science and Technology’s Grant-in-Aid for Scientific Research in Japan.
Author : Giovanna Orsini
Publisher : Frontiers Media SA
Page : 248 pages
File Size : 47,97 MB
Release : 2016-10-07
Category : Physiology
ISBN : 2889199843
Sequential and reciprocal interactions between oral epithelial and cranial neural crest-derived mesenchymal cells give rise to the teeth and periodontium. Teeth are vital organs containing a rich number of blood vessels and nerve fibers within the dental pulp and periodontium. Teeth are composed by unique and specific collagenous (dentin, fibrillar cementum) and non-collagenous (enamel) highly mineralized extracellular matrices. Alveolar bone is another collagenous hard tissue that supports tooth stability and function through its close interaction with the periodontal ligament. Dental hard tissues are often damaged after infection or traumatic injuries that lead to the partial or complete destruction of the functional dental and supportive tissues. Well-established protocols are routinely used in dental clinics for the restoration or replacement of the damaged tooth and alveolar bone areas. Recent progress in the fields of cell biology, tissue engineering, and nanotechnology offers promising opportunities to repair damaged or missing dental tissues. Indeed, pulp and periodontal tissue regeneration is progressing rapidly with the application of stem cells, biodegradable scaffolds, and growth factors. Furthermore, methods that enable partial dental hard tissue repair and regeneration are being evaluated with variable degrees of success. However, these cell-based therapies are still incipient and many issues need to be addressed before any clinical application. The understanding of tooth and periodontal tissues formation would be beneficial for improving regenerative attempts in dental clinics. In the present e-book we have covered the various aspects dealing with dental and periodontal tissues physiology and regeneration in 6 chapters: 1. General principles on the use of stem cells for regenerating craniofacial and dental tissues 2. The roles of nerves, vessels and stem cell niches in tissue regeneration 3. Dental pulp regeneration and mechanisms of various odontoblast functions 4. Dental root and periodontal physiology, pathology and regeneration 5. Physiology and regeneration of the bone using various scaffolds and stem cell populations 6. Physiology, pathology and regeneration of enamel using dental epithelial stem cells
Author : A.J. Tallón-Ballesteros
Publisher : IOS Press
Page : 696 pages
File Size : 32,56 MB
Release : 2022-12-29
Category : Computers
ISBN : 1643683691
Electronics, communication and networks coexist, and it is not possible to conceive of our current society without them. Within the next decade we will probably see the consolidation of 6G-based technology, accompanied by many compatible devices, and fiber-optic is already an advanced technology with many applications. This book presents the proceedings of CECNet 2022, the 12th International Conference on Electronics, Communications and Networks, held as a virtual event with no face-to-face participation in Xiamen, China, from 4 to 7 November 2022. CECNet is held annually, and covers many interrelated groups of topics such as electronics technology, communication engineering and technology, wireless communications engineering and technology and computer engineering and technology. This year the conference committee received 313 submissions. All papers were carefully reviewed by program committee members, taking into consideration the breadth and depth of research topics falling within the scope of the conference, and after further discussion, 79 papers were selected for presentation at the conference and for publication in this book. This represents an acceptance rate of about 25%. The book offers an overview of the latest research and developments in these rapidly evolving fields, and will be of interest to all those working with electronics, communication and networks.
Author : Lulu Wang
Publisher : BoD – Books on Demand
Page : 112 pages
File Size : 30,3 MB
Release : 2020-03-18
Category : Medical
ISBN : 1838802428
This book aims to provide a brief update to the current status of and advances in computational methods and programs used for the development of the theory and practice of biomedical signal and image communication. The book comprises a collection of invited manuscripts, written in a convenient way and of manageable length. These timely collections will provide an invaluable resource for initial inquiries into technologies and will encapsulate the latest developments and applications with reference sources for further detailed information. The methods described in this book cover a wide range of computational algorithms that are widely used in bioengineering and biomedicine. The content and format are specifically designed to stimulate the further development and application of these technologies by reaching out to non-specialists across a broad audience. This book is intended to expose the latest developments of scientists and engineers covering a variety of complementary topics, to enhance people's overall understanding of computer science and biomedical image communications. It will benefit students, scientists, and researchers in applied computer science. Engineers and clinicians working in imaging will also find this book useful.
Author : Andrzej Świerniak
Publisher : Springer
Page : 241 pages
File Size : 43,17 MB
Release : 2016-05-19
Category : Mathematics
ISBN : 3319280953
This book focuses on the analysis of cancer dynamics and the mathematically based synthesis of anticancer therapy. It summarizes the current state-of-the-art in this field and clarifies common misconceptions about mathematical modeling in cancer. Additionally, it encourages closer cooperation between engineers, physicians and mathematicians by showing the clear benefits of this without stating unrealistic goals. Development of therapy protocols is realized from an engineering point of view, such as the search for a solution to a specific control-optimization problem. Since in the case of cancer patients, consecutive measurements providing information about the current state of the disease are not available, the control laws are derived for an open loop structure. Different forms of therapy are incorporated into the models, from chemotherapy and antiangiogenic therapy to immunotherapy and gene therapy, but the class of models introduced is broad enough to incorporate other forms of therapy as well. The book begins with an analysis of cell cycle control, moving on to control effects on cell population and structured models and finally the signaling pathways involved in carcinogenesis and their influence on therapy outcome. It also discusses the incorporation of intracellular processes using signaling pathway models, since the successful treatment of cancer based on analysis of intracellular processes, might soon be a reality. It brings together various aspects of modeling anticancer therapies, which until now have been distributed over a wide range of literature. Written for researchers and graduate students interested in the use of mathematical and engineering tools in biomedicine with special emphasis on applications in cancer diagnosis and treatment, this self-contained book can be easily understood with only a minimal basic knowledge of control and system engineering methods as well as the biology of cancer. Its interdisciplinary character and the authors’ extensive experience in cooperating with clinicians and biologists make it interesting reading for researchers from control and system engineering looking for applications of their knowledge. Systems and molecular biologists as well as clinicians will also find new inspiration for their research.
