Fraud in the Lab


Book Description

From manipulated results and fake data to retouched illustrations and plagiarism, cases of scientific fraud have skyrocketed in the past two decades. In a damning exposé, Nicolas Chevassus-au-Louis details the circumstances enabling the decline in scientific standards and highlights efforts to curtail future misconduct.




Fraud in the Lab


Book Description

From a journalist and former lab researcher, a penetrating investigation of the explosion in cases of scientific fraud and the factors behind it. In the 1970s, a scientific scandal about painted mice hit the headlines. A cancer researcher was found to have deliberately falsified his experiments by coloring transplanted mouse skin with ink. This widely publicized case of scientific misconduct marked the beginning of an epidemic of fraud that plagues the scientific community today. From manipulated results and made-up data to retouched illustrations and plagiarism, cases of scientific fraud have skyrocketed in the past two decades, especially in the biomedical sciences. Fraud in the Lab examines cases of scientific misconduct around the world and asks why this behavior is so pervasive. Nicolas Chevassus-au-Louis points to large-scale trends that have led to an environment of heightened competition, extreme self-interest, and emphasis on short-term payoffs. Because of the move toward highly specialized research, fewer experts are qualified to verify experimental findings. And the pace of journal publishing has exacerbated the scientific rewards system—publish or perish holds sway more than ever. Even when instances of misconduct are discovered, researchers often face few consequences, and falsified data may continue to circulate after an article has been retracted. Sharp and damning, this exposé details the circumstances that have allowed scientific standards to decline. Fraud in the Lab reveals the intense social pressures that lead to fraud, documents the lasting impact it has had on the scientific community, and highlights recent initiatives and proposals to reduce the extent of misconduct in the future.




Science Fictions


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Bad Blood


Book Description

NATIONAL BESTSELLER • The gripping story of Elizabeth Holmes and Theranos—one of the biggest corporate frauds in history—a tale of ambition and hubris set amid the bold promises of Silicon Valley, rigorously reported by the prize-winning journalist. With a new Afterword covering her trial and sentencing, bringing the story to a close. “Chilling ... Reads like a thriller ... Carreyrou tells [the Theranos story] virtually to perfection.” —The New York Times Book Review In 2014, Theranos founder and CEO Elizabeth Holmes was widely seen as the next Steve Jobs: a brilliant Stanford dropout whose startup “unicorn” promised to revolutionize the medical industry with its breakthrough device, which performed the whole range of laboratory tests from a single drop of blood. Backed by investors such as Larry Ellison and Tim Draper, Theranos sold shares in a fundraising round that valued the company at more than $9 billion, putting Holmes’s worth at an estimated $4.5 billion. There was just one problem: The technology didn’t work. Erroneous results put patients in danger, leading to misdiagnoses and unnecessary treatments. All the while, Holmes and her partner, Sunny Balwani, worked to silence anyone who voiced misgivings—from journalists to their own employees.




Plastic Fantastic


Book Description

Discusses the scientific scandal that arose when researchers at Bell Laboratories discovered that wunderkind physicist Jan Hendrik Schön falsified his data to prove that he had discovered a simpler way to make transistors, which would have drastically improved energy technology.




On Fact and Fraud


Book Description

An in-depth look at scientific fraud Fraud in science is not as easy to identify as one might think. When accusations of scientific misconduct occur, truth can often be elusive, and the cause of a scientist's ethical misstep isn't always clear. On Fact and Fraud looks at actual cases in which fraud was committed or alleged, explaining what constitutes scientific misconduct and what doesn't, and providing readers with the ethical foundations needed to discern and avoid fraud wherever it may arise. In David Goodstein's varied experience—as a physicist and educator, and as vice provost at Caltech, a job in which he was responsible for investigating all allegations of scientific misconduct—a deceptively simple question has come up time and again: what constitutes fraud in science? Here, Goodstein takes us on a tour of real controversies from the front lines of science and helps readers determine for themselves whether or not fraud occurred. Cases include, among others, those of Robert A. Millikan, whose historic measurement of the electron's charge has been maligned by accusations of fraud; Martin Fleischmann and Stanley Pons and their "discovery" of cold fusion; Victor Ninov and the supposed discovery of element 118; Jan Hendrik Schön from Bell Labs and his work in semiconductors; and J. Georg Bednorz and Karl Müller's discovery of high-temperature superconductivity, a seemingly impossible accomplishment that turned out to be real. On Fact and Fraud provides a user's guide to identifying, avoiding, and preventing fraud in science, along the way offering valuable insights into how modern science is practiced.




Honor in Science


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The Baltimore Case: A Trial of Politics, Science, and Character


Book Description

"You read with a rising sense of despair and outrage, and you finish it as if awakening from a nightmare only Kafka could have conceived."--Christopher Lehmann-Haupt, New York Times David Baltimore won the Nobel Prize in medicine in 1975. Known as a wunderkind in the field of immunology, he rose quickly through the ranks of the scientific community to become the president of the distinguished Rockefeller University. Less than a year and a half later, Baltimore resigned from his presidency, citing the personal toll of fighting a long battle over an allegedly fraudulent paper he had collaborated on in 1986 while at MIT. From the beginning, the Baltimore case provided a moveable feast for those eager to hold science more accountable to the public that subsidizes its research. Did Baltimore stonewall a legitimate government inquiry? Or was he the victim of witch hunters? The Baltimore Case tells the complete story of this complex affair, reminding us how important the issues of government oversight and scientific integrity have become in a culture in which increasingly complicated technology widens the divide between scientists and society.




The Lab


Book Description

The Lab explains the idea of the “culture lab,” Edwards’ concept for experimental art and design centers like those he recently founded in Paris and at Harvard. He presents the lab as a new kind of educational art studio based on a contemporary science lab model, and he shows how students learn by translating ideas alongside experienced creators by exhibiting risky experimental processes in gallery settings.




Fostering Integrity in Research


Book Description

The integrity of knowledge that emerges from research is based on individual and collective adherence to core values of objectivity, honesty, openness, fairness, accountability, and stewardship. Integrity in science means that the organizations in which research is conducted encourage those involved to exemplify these values in every step of the research process. Understanding the dynamics that support â€" or distort â€" practices that uphold the integrity of research by all participants ensures that the research enterprise advances knowledge. The 1992 report Responsible Science: Ensuring the Integrity of the Research Process evaluated issues related to scientific responsibility and the conduct of research. It provided a valuable service in describing and analyzing a very complicated set of issues, and has served as a crucial basis for thinking about research integrity for more than two decades. However, as experience has accumulated with various forms of research misconduct, detrimental research practices, and other forms of misconduct, as subsequent empirical research has revealed more about the nature of scientific misconduct, and because technological and social changes have altered the environment in which science is conducted, it is clear that the framework established more than two decades ago needs to be updated. Responsible Science served as a valuable benchmark to set the context for this most recent analysis and to help guide the committee's thought process. Fostering Integrity in Research identifies best practices in research and recommends practical options for discouraging and addressing research misconduct and detrimental research practices.