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Frontiers in Cardiovascular Drug Discovery

Author : Atta-ur-Rahman

Publisher : Bentham Science Publishers

Page : 406 pages

File Size : 15,63 MB

Release : 2016-11-01

Category : Medical

ISBN : 1681081636

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Book Description

Frontiers in Cardiovascular Drug Discovery is an eBook series devoted to publishing the latest advances in cardiovascular drug design and discovery. Each volume brings reviews on the biochemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships of molecules used in cardiovascular therapy. The eBook series should prove to be of great interest to all medicinal chemists and pharmaceutical scientists involved in preclinical and clinical research in cardiology. The third volume of the series covers the following topics: - P2Y12 receptor agonists -Heart failure pharmacotherapy -Vasopressin and the cardiovascular system -Cerebral small vessel disease -Complement blocking therapeutic strategies -New antiplatelet and anticoagulating agents for gastrointestinal treatments



Frontiers in Cardiovascular Drug Discovery

Author : Atta-ur- Rahman

Publisher : Bentham Science Publishers

Page : 359 pages

File Size : 29,48 MB

Release : 2011-08-11

Category : Medical

ISBN : 1608051609

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Book Description

"Frontiers in Cardiovascular Drug Discovery" is an Ebook series devoted to publishing the latest and the most important advances in Cardiovascular drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and d





Drug Repositioning: Current Advances and Future Perspectives

Author : Yuhei Nishimura

Publisher : Frontiers Media SA

Page : 153 pages

File Size : 23,18 MB

Release : 2019-01-11

Category :

ISBN : 288945696X

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Book Description

Drug repositioning is the process of identifying new indications for existing drugs. At present, the conventional de novo drug discovery process requires an average of about 14 years and US$2.5 billion to approve and launch a drug. Drug repositioning can reduce the time and cost of this process because it takes advantage of drugs already in clinical use for other indications or drugs that have cleared phase I safety trials but have failed to show efficacy in the intended diseases. Historically, drug repositioning has been realized through serendipitous clinical observations or improved understanding of disease mechanisms. However, recent technological advances have enabled a more systematic approach to drug repositioning. This eBook collects 16 articles from 112 authors, providing readers with current advances and future perspectives of drug repositioning.



Current and Future Role of Artificial Intelligence in Cardiac Imaging

Author : Steffen Erhard Petersen

Publisher : Frontiers Media SA

Page : 138 pages

File Size : 15,86 MB

Release : 2020-10-09

Category : Medical

ISBN : 2889660583

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Book Description

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.



Frontiers in Cardiovascular Drug Discovery: Volume 5

Author : Atta-ur-Rahman

Publisher : Bentham Science Publishers

Page : 278 pages

File Size : 21,59 MB

Release : 2020-10-02

Category : Medical

ISBN : 9811413231

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Book Description

Frontiers in Cardiovascular Drug Discovery is a book series devoted to publishing the latest advances in cardiovascular drug design and discovery. Each volume brings reviews on the biochemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships of molecules used in cardiovascular therapy. The book series should prove to be of great interest to all medicinal chemists and pharmaceutical scientists involved in preclinical and clinical research in cardiology. The fifth volume of the series covers the following topics: -The Lipid Hypothesis: From Resins to Proprotein Convertase Subtilisin/Kexin Type-9 Inhibitors -The Role of SGLT2i in the Prevention and Treatment of Heart Failure -Natural Products and Semi-Synthetic Compounds as Antithrombotics: A Review of the Last Ten Years (2009-2019) -Transient Receptor Potential Channels: Therapeutic Targets for Cardiometabolic Diseases? -Treatment of Raynaud’s Phenomenon -Traditional Medicine Based Cardiovascular Therapeutics -Cardiovascular Disease: A Systems Biology Approach



Frontiers in Cardiovascular Drug Discovery: Volume 6

Author : M. Iqbal Choudhary

Publisher : Bentham Science Publishers

Page : 256 pages

File Size : 31,43 MB

Release : 2022-11-11

Category : Medical

ISBN : 9815036912

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Book Description

Frontiers in Cardiovascular Drug Discovery is a book series devoted to publishing the latest advances in cardiovascular drug design and discovery. Each volume brings reviews on the biochemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships of molecules used in cardiovascular therapy. The book series should prove to be of great interest to all medicinal chemists and pharmaceutical scientists involved in preclinical and clinical research in cardiology. Volume 6 covers the following topics: - Cardiovascular effects of ranolazine and the scope for translational research: a current review of literature - Rho/Rho kinase signaling pathway and disease: - Hibernation or transformation? Challenges in cardiovascular drug development - New approaches in P2Y12 receptor blocker drugs use - Pathophysiological links between diabetes and cardiovascular diseases: at the biochemical and molecular levels



Frontiers in Cardiovascular Drug Discovery: Volume 4

Author : Atta-ur-Rahman

Publisher : Bentham Science Publishers

Page : 206 pages

File Size : 12,37 MB

Release : 2019-04-05

Category : Medical

ISBN : 1681084007

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Book Description

Frontiers in Cardiovascular Drug Discovery is an eBook series devoted to publishing the latest advances in cardiovascular drug design and discovery. Each volume brings reviews on the biochemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships of molecules used in cardiovascular therapy. The eBook series should prove to be of great interest to all medicinal chemists and pharmaceutical scientists involved in preclinical and clinical research in cardiology. The fourth volume of the series covers the following topics: -Aspirin administration -Adenosine receptor targeting for cardiovascular therapy -Drug treatment of patients with coronary stenting -Immunosuppressive drugs in heart transplantation -PCSK9 inhibition for lowering LDL-C levels.



Cardio-Oncology: From Bench to Bedside

Author : Jun-ichi Abe

Publisher :

Page : 0 pages

File Size : 10,94 MB

Release : 2019

Category :

ISBN :

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Book Description

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.



Antibody-Drug Conjugates

Author : Kenneth J. Olivier, Jr.

Publisher : John Wiley & Sons

Page : 567 pages

File Size : 43,29 MB

Release : 2016-11-14

Category : Medical

ISBN : 1119060842

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Book Description

Providing practical and proven solutions for antibody-drug conjugate (ADC) drug discovery success in oncology, this book helps readers improve the drug safety and therapeutic efficacy of ADCs to kill targeted tumor cells. • Discusses the basics, drug delivery strategies, pharmacology and toxicology, and regulatory approval strategies • Covers the conduct and design of oncology clinical trials and the use of ADCs for tumor imaging • Includes case studies of ADCs in oncology drug development • Features contributions from highly-regarded experts on the frontlines of ADC research and development