Handbook of Histology Methods for Bone and Cartilage


Book Description

Histotechnology and histomorphometry are the major methodologies in bone and cartila- related research. Handbook of Histology Methods for Bone and Cartilage is an outgrowth of the editors’ own quest for information on bone and cartilage histology and histomorphometry. It is designed to be an experimental guide for personnel who work in the areas of basic and clinical bone and cartilage, orthopedic, or dental research. It is the first inclusive and organized reference book on histological and histomorphometrical techniques on bone and cartilage specimens. The topic has not previously been covered adequately by any existing books in the field. Handbook of Histology Methods for Bone and Cartilage has six major parts and is designed to be concise as well as inclusive, and more practical than theoretical. The text is simple and straightforward. Large numbers of tables, line drawings, and micro- or macro-photographs, are used to help readers better understand the content. Full bibliographies at the end of each chapter guide readers to more detailed information. A book of this length cannot discuss every method for bone and cartilage histology that has been used over the years, but it is hoped that major methods and their applications have been included.




Bone Remodeling Process


Book Description

Bone Remodeling Process: Mechanics, Biology, and Numerical Modeling provides a literature review. The first part of the book discusses bones in a normal physiological condition, bringing together the involved actors and factors reported over the past two decades, and the second discusses pathological conditions, highlighting the attack vectors of each bone disease. The third part is devoted to the mathematical descriptions of bone remodeling, formulated to develop models able to provide information that is not amenable to direct measurement, while the last part focuses on models using the finite element method in investigating bone biomechanics.This book creates an overall image of the complex communication network established between the diverse remodeling actors, based on overwhelming control evidence revealed over recent years, as well as visualizes the remodeling defects and possible treatments in each case. It also regroups the models allowing readers to analyze and assess bone mechanical and biological properties. This book details the cellular mechanisms allowing the bone to adapt its microarchitecture to the requirements of the human body, which is the main issue in bone biology and presents the evolution of mathematical modeling used in a bone computer simulation. - Each chapter covers a core topic in bone biomechanics - Provides a multidisciplinary view that effectively links orthopaedics, cellular biology, mechanics, and computer simulation - Draws an overall image about bone biology and cell interactions, for identifying cell populations that are crucial for the remodeling process




Review in Oral and Maxillofacial Surgery


Book Description

This book explores all the topics of Oral and Maxillofacial Surgery, from basics to recent concepts like Distraction Osteogenesis and Osseointegration helpful for undergraduate examinations and various MDS entrance examinations. This is an attempt to solve the difficulty faced by students in their pursuit of excellence in these examinations. The text will help the readers to get a command over the examination technique and also clarify questions that otherwise appear confusing. The text will also help students to judge their preparations after the study of theory is over.




ImmunoPharmaceuticals


Book Description

Written by a leading researcher in immunology, ImmunoPharmaceuticals specifically focuses on immunologically active drugs recently tested for clinical activity or recently approved for medical use. Each chapter focuses on a single drug or class of drugs and discusses data from basic and preclinical research concerning mechanisms of action. Preclinical models are compared with clinical findings to allow the reader to evaluate the predictive value of those models. Featured drugs are being studied for therapy of cancer, arthritic disease, autoimmune disease, immunodeficiency disease, transplantation, and determination of sepsis. Overviews of the retinoids in cancer therapy and preclinical studies on flavonoids are featured.




Tissue and Cell Clinical Use


Book Description

This new book explores clinical information in the tissue transplantation field and acts as a comprehensive learning tool to comply with regulatory requirements. Broad in scope, coverage includes all the traditionally transplanted tissues and moves into more complex areas of tissue grafting and the assisted reproduction fields. This useful text focuses on the potential for disease transmission, ways to improve safety, and the role of the clinician in these safety aspects. The book starts off by describing non-surgical risks of using allografts and moves onto chapters devoted completely to tissue- or cell-specific issues relating to transplantation of the individual types of tissues or cells. Tissue and Cell Clinical Use: An Essential Guide is the final book in a series which covers all aspects of tissue banking, donation, processing, and transplantation. Each book in the series includes lists of learning points and case studies which consist of sample processing protocols, descriptions of where processing went wrong, sample risk assessments, or validation studies. This three book series covers all you need to know about tissue banking.




Adipose-Derived Stem Cells


Book Description

During the past decade, a wide range of scientific disciplines have adopted the use of adipose-derived stem/stromal cells (ASCs) as an important tool for research and discovery. In Adipose-Derived Stem Cells: Methods and Protocols, experts from the field, including members of the esteemed International Federation of Adipose Therapeutics and Science (IFATS), provide defined and established protocols in order to further codify the utilization of these powerful and accessible cells. With chapters organized around approaches spanning the discovery, pre-clinical, and clinical processes, much of the emphasis is placed on human ASC, while additional techniques involving small and large animal species are included. As a volume in the highly successful Methods in Molecular BiologyTM series, the detailed contributions include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Adipose-Derived Stem Cells: Methods and Protocols serves as a vital reference text for experienced researchers as well as new students on the path to further exploring the incredible potential of ASCs.




Forensic Taphonomy


Book Description

Links have recently been established between the study of death assemblages by archaeologists and paleontologists (taphonomy) and the application of physical anthropology concepts to the medicolegal investigation of death (forensic anthropology). Forensic Taphonomy explains these links in a broad-based, multidisciplinary volume. It applies taphonomic models in modern forensic contexts and uses forensic cases to extend taphonomic theories. Review articles, case reports, and chapters on methodology round out this book's unique approach to forensic science.




Manual of Forensic Taphonomy


Book Description

The main goals in any forensic skeletal analysis are to answer who is the person represented (individualization), how that person died (trauma/pathology) and when that person died (the postmortem interval or PMI). The analyses necessary to generate the biological profile include the determination of human, nonhuman or nonosseous origin, the minimum number of individuals represented, age at death, sex, stature, ancestry, perimortem trauma, antemortem trauma, osseous pathology, odontology, and taphonomic effects—the postmortem modifications to a set of remains. The Manual of Forensic Taphonomy, Second Edition covers fundamental principles of these postmortem changes encountered during case analysis. Taphonomic processes can be highly destructive and subtract information from bones regarding their utility in determining other aspects of the biological profile, but they also can add information regarding the entire postmortem history of the remains and the relative timing of these effects. The taphonomic analyses outlined provide guidance on how to separate natural agencies from human-caused trauma. These analyses are also performed in conjunction with the field processing of recovery scenes and the interpretation of the site formation and their postdepositional history. The individual chapters categorize these alterations to skeletal remains, illustrate and explain their significance, and demonstrate differential diagnosis among them. Such observations may then be combined into higher-order patterns to aid forensic investigators in determining what happened to those remains in the interval from death to analysis, including the environment(s) in which the remains were deposited, including buried, terrestrial surface, marine, freshwater, or cultural contexts. Features Provides nearly 300 full-color illustrations of both common and rare taphonomic effects to bones, derived from actual forensic cases. • Presents new research including experimentation on recovery rates during surface search, timing of marine alterations, trophy skulls, taphonomic laboratory and field methods, laws regarding the relative timing of taphonomic effects, reptile taphonomy, human decomposition, and microscopic alterations by invertebrates to bones. • Explains and illustrates common taphonomic effects and clarifies standard terminology for uniformity and usage within in the field. While the book is primarily focused upon large vertebrate and specifically human skeletal remains, it effectively synthesizes data from human, ethological, geological/paleontological, paleoanthropological, archaeological artifactual, and zooarchaeological studies. Since these taphonomic processes affect other vertebrates in similar manners, The Manual of Forensic Taphonomy, Second Edition will be invaluable to a broad set of forensic and investigative disciplines.




Russell, Hugo and Ayliffe's Principles and Practice of Disinfection, Preservation and Sterilization


Book Description

The new edition of this established and highly respected text is THE definitive reference in its field. It details methods for the elimination or prevention/control of microbial growth, and features: New chapters on bioterrorism and community healthcare New chapters on microbicide regulations in the EU, USA and Canada Latest material on microbial resistance to microbicides Updated material on new and emerging technologies, focusing on special problems in hospitals, dentistry and pharmaceutical practice Practical advice on problems of disinfection and antiseptics in healthcare A systematic review of sterilization methods, with uses and advantages outlined for each Evaluation of disinfectants and their mechanisms of action with respect to current regulations The differences between European and North American regulations are highlighted throughout, making this a truly global work, ideal for worldwide healthcare professionals working in infectious diseases and infection control.




Frozen Section Pathology


Book Description

This book provides guidance regarding the approach to common scenarios encountered in the frozen section laboratory while underscoring diagnostic pitfalls and providing the proper level of diagnostic information to ensure clear communication. Given the use of frozen section in molecular and research pathology, the text also serves as a guide for morphologic examination. Written by experts in the field, the book is organized according to organ system with additional chapters discussing the roles of digital pathology and molecular assays. Each chapter is extensively illustrated to highlight key points that facilitate interpretation and highlight areas for potential error. The goal of this book is to help trainees understand the need for mastery of this unique diagnostic tool, and to aid pathologists who cover frozen section convert practical information provided into diagnostic improvements. Frozen Section Pathology is a comprehensive and state-of-the-art review and serves as a valuable resource for the general surgical pathologist with frozen section responsibilities as well as surgeons who regularly utilize frozen section.