Innovative Medicine


Book Description

This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.




Fructose-2,6-Bisphosphate


Book Description

This reference volume follows the Fructose-2, 6-P2 story from its discovery in 1980 to current studies on the enzyme systems responsible for its synthesis and degradation. The book begins with a historical perspective on the discovery of the compound and then proceeds to its chemistry and number of derivatives. It includes a detailed treatment of the role of the compound in the regulation of carbohydrate metabolism in various tissues and organisms. A portion of this work is devoted to characterization of the enzyme activities responsible for its synthesis and degradation. This detailed, yet comprehensive work is helpful for all biochemists, experimental biologists, and biophysicists.




Biochemistry for Medical Professionals


Book Description

Biochemistry for Medical Professionals contains pivotal advances in the biochemistry field and provides a resource for professionals across medicine, dentistry, pharmaceutical sciences and health professions who need a concise, topical biochemistry reference. Relevant, well-illustrated coverage begins with the composition of the human body and then goes into the technical detail of the metabolism of the human body and biochemistry of internal organs before featuring a biotechnology study inclusive of numerous methods and applications. The work is written at a consistently high level, with technical notes added to aid comprehension for complex topics. - Illustrates disease involvement in metabolic maps - Contains coverage of cutting-edge technology, including iPS, HPLC and HPLC-MS, and FACS method - Provides in-depth technical detail as well as conceptual frameworks of biochemistry and experimental design in the context of the human organism - Includes a biotechnology study, featuring application of basic biochemistry principles




Elsevier's Integrated Review Biochemistry


Book Description

Effectively merge basic science and clinical skills with Elsevier's Integrated Review Biochemistry, by John W. Pelley, PhD. This concise, high-yield title in the popular Integrated Review Series focuses on the core knowledge in biochemistry while linking that information to related concepts from other basic science disciplines. Case-based questions at the end of each chapter enable you to gauge your mastery of the material, and a color-coded format allows you to quickly find the specific guidance you need. Online access via www.studentconsult.com - included with your purchase - allows you to conveniently access the book's complete text and illustrations online as well as relevant content from other Student Consult titles. This concise and user-friendly reference provides crucial guidance for the early years of medical training and USMLE preparation. Spend more time reviewing and less time searching thanks to an extremely focused, "high-yield" presentation. Gauge your mastery of the material and build confidence with both case-based, andUSMLE-style questions that provide effective chapter review and quick practice for your exams. Access the full contents online at www.studentconsult.com where you'll find the complete text and illustrations, "Integration Links" to bonus content in other Student Consult titles, an interactive community center with a wealth of additional resources, and much more! Grasp and retain vital concepts more easily thanks to a color-coded format, succinct,text, key concept boxes, and dynamic illustrations that facilitate learning in a highly visual approach. Effectively review for problem-based courses with the help of text boxes that help you clearly see the clinical relevance of the material. Great for visual learners!




The Heterogeneity of Cancer Metabolism


Book Description

Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.




Cells: Molecules and Mechanisms


Book Description

"Yet another cell and molecular biology book? At the very least, you would think that if I was going to write a textbook, I should write one in an area that really needs one instead of a subject that already has multiple excellent and definitive books. So, why write this book, then? First, it's a course that I have enjoyed teaching for many years, so I am very familiar with what a student really needs to take away from this class within the time constraints of a semester. Second, because it is a course that many students take, there is a greater opportunity to make an impact on more students' pocketbooks than if I were to start off writing a book for a highly specialized upper- level course. And finally, it was fun to research and write, and can be revised easily for inclusion as part of our next textbook, High School Biology."--Open Textbook Library.




Rapid Review Biochemistry E-Book


Book Description

Get the most from your study time, and experience a realistic USMLE simulation with Rapid Review Biochemistry, 3rd Edition, by Drs. John W. Pelley, and Edward F. Goljan. This new reference in the highly rated Rapid Review Series is formatted as a bulleted outline with photographs, tables, and figures that address all the biochemistry information you need to know for the USMLE. And with Student Consult functionality, you can become familiar with the look and feel of the actual exam by taking a timed or a practice online test that includes 350 USMLE-style questions. Author, John Pelley, wins 2010 Alpha Omega Alpha Robert J. Glaser Distinguished Teacher Award John Pelley PhD, an associate author of two popular medical review titles, Rapid Review Biochemistry, and Elsevier's Integrated Review Biochemistry has won the 2010 Alpha Omega Alpha (AOA) Robert J. Glaser Distinguished Teacher Award. The award was established by the AOA medical honor society in 1988 to recognize faculty members who have distinguished themselves in medical student education. He is nationally known for applying concept mapping, a learning technique that focuses on building patterns and relationships to concepts, to medical education. - Review the most current information with completely updated chapters, images, and questions. - Profit from the guidance of series editor, Dr. Edward Goljan, a well-known author of medical review books, who reviewed and edited every question. - Take a timed or a practice test online with more than 350 USMLE-style questions and full rationales for why every possible answer is right or wrong. - Access all the information you need to know quickly and easily with a user-friendly, two-color outline format that includes High-Yield Margin Notes. - Study and take notes more easily with the new, larger page size. - Practice with a new testing platform on USMLE Consult that gives you a realistic review experience and fully prepares you for the exam.




Biology for AP ® Courses


Book Description

Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.




Passing the USMLE


Book Description

Preparing for the USMLE can be a stressful and time consuming task for any medical student. The key elements of a successful review program are clarity, brevity and memory-assisting consistency. The author of Passing the USMLE: Clinical Knowledge has taken great pains to distill an ocean of knowledge down to the fundamental clinical applications of patient care. Covering internal medicine, dermatology, obstetrics, gynecology, surgery, pediatrics and psychology, a wealth of high yield information is presented so the reader takes away as much as possible from every word, every sentence, and every minute spent studying. Passing the USMLE: Clinical Knowledge is illustrated throughout with full color photographs and illustrations.




Inborn Metabolic Diseases


Book Description

Each disease-related chapter begins with a detailed description of the patient and the delineating symptoms used for establishing the diagnosis and differential diagnosis. The highly detailed figures illustrate the metabolic derangement in a uniform way, together with essential aspects of the genetics involved, thus affording clarification and better understanding of the treatment. Topics covered range from general aspects such as the clinical approach, emergency treatment, diagnostic procedures, and psychosocial care for the child and the family, to specific discussions of new modes of treatment, including liver, bone marrow transplantation and somatic gene therapy.