The Overlooked Individual: Susceptibility to Dental Caries, Erosive Tooth Wear and Amelogenesis


Book Description

Individual susceptibility to disease (i.e., one’s own genetic background) is one of the three main components classically described in the etiology of dental caries. Hence, genes influence susceptibility to erosive tooth wear, dental development, and response to treatments and interventions. This publication is an up-to-date overview of individual susceptibility to dental caries, erosive tooth wear, and disturbances of dental development from different clinically relevant perspectives. One of the most recognized scientists in this field reports on recent research relating to human genetics – from general summaries to recommendations for daily clinical work and population-level interventions. This book covers all aspects of individual susceptibility to dental caries and erosive tooth wear. Several chapters deal with potential biological mechanisms, with additional ones providing a strong foundation in human genetics, and other chapters touch on efficacy of therapies and alternative concepts. This book is particularly recommended to dental medicine students, practitioners, other oral healthcare professionals, and scientists with an interest in translational research on dental caries and erosive tooth wear.




Genetic Basis of Oral Health Conditions


Book Description

This book explains the genetic basis of a wide range of dental disorders, including dental caries, periodontitis, congenital anomalies, malocclusions, orofacial pain, dental implant failure, and cancer. Such conditions are typically multifactorial or complex, with involvement of more than one gene as well as environmental influences. A sound grasp of this framework is ever more important, given the emergence of consumer genomics, including direct-to-consumer genetic testing. Dental professionals now need to understand why one person is susceptible to a particular oral health condition while a first-degree relative either does not develop the condition or does so in a less severe form. Knowledge of how genes operate in the susceptible host is essential if patients are to be offered accurate advice about their risks. The information provided in this book will assist in the delivery of effective personalized dental care through optimization of preventive strategies. It will enable the practitioner to explain the extent to which a patient’s condition is pure "bad luck", whether that bad luck can be changed by behavioral choices, and how many of our behaviors are influenced by genes.




Erosive Tooth Wear


Book Description

Erosive tooth wear is a multifactorial condition of growing concern to the clinician and the subject of extensive research. Since the publication of the first edition of the book with the title Dental Erosion, new knowledge for a better understanding of this important subject has been gathered. The new and more detailed insights resulted in this second, extended publication. It presents a broad spectrum of views, from the molecular level to behavioural aspects, as well as trends in society. In particular, the issues concerning chemical and biological factors as well as dental erosion in children are covered more extensively in this second edition. The first chapters include topics such as the definition, diagnosis, interaction, epidemiology and histopathology of tooth wear. Further, the aetiology of dental erosion, including nutritional and patient-related factors, and dental erosion in children are discussed. This book is a valuable and indispensable guide to better oral health and is highly recommended to faculty members, researchers, dental students, practitioners and other dental professionals.




Oral Biofilms


Book Description

Biofilms are highly organized polymicrobial communities that are embedded in an extracellular matrix and formed on natural and artificial surfaces. In the oral cavity, biofilms are formed not only on natural teeth, but also on restorative materials, prosthetic constructions, and dental implants. Oral diseases like caries, gingivitis, periodontitis, and also pulp inflammation are associated with biofilms. This publication is an up-to-date overview on oral biofilms from different clinically relevant perspectives. Experts comprising basic researchers and clinicians report on recent research relating to biofilms - from general summaries to recommendations for daily clinical work. This book covers all aspects of oral biofilms, including models used in the laboratory, biofilms in dental water unit lines, periodontal and peri-implant biofilms, caries-related biofilms, halitosis, endodontic biofilms, and Candida infections, as well as biofilms on dental materials and on orthodontic appliances. Several chapters deal with anti-biofilm therapy, from the efficacy of mechanical methods and the use of antimicrobials, to alternative concepts. This publication is particularly recommended to dental medicine students, practitioners, other oral healthcare professionals, and scientists with an interest in translational research on biofilms.




Genetics in Dentistry


Book Description




Dental Anthropology


Book Description

Shelley Saunders This book offers a welcome diversity of topics covering the broader subjects of teeth and the study of teeth by anthropologists. There is an impressive array of coverage here including the history of anthropological study of the teeth, morphology and structure, pathology and epidemiology, the relationship between nutrition, human behavior and the dentition, age and sex estimation from teeth, and geographic and genetic variation. Most chapter authors have provided thorough reviews of their subjects along with examples of recent analytical work and recommendations for future research. North American researchers should particularly appreciate the access to an extensive European literature cited in the individual chapter bibliographies. Physical anthropologists with even a passing interest in dental research should greet the publication of this book with pleasure since it adds to a growing list of books on how the study of teeth can tell us so much about past human populations. In addition to the archaeological applications, there is the forensic objective of dental anthropology which the editors refer to in their introduction which is dealt with in this volume. The chapters dealing with methods of sex determination, age estimation of juveniles and age estimation of adults using the teeth are exhaustive and exacting and of critical importance to both "osteoarchaeologists" and forensic anthropologists. Authors Liversidge, Herdeg and Rosing provide very clear guidelines for the use of dental formation standards in juvenile age estimation, recommendations that are so obviously necessary at this time.




Personalized Oral Health Care


Book Description

This book provides an overview of the oral health care environment as the transition is made to a system increasingly focusing on disease prevention, early intervention to minimize disease progression, and a personalized approach that meets each individual’s needs. Descriptions are provided of an array of technologies based on rapid advances in genomic medicine and omics technology that are already entering clinical practice and promise to have a huge impact on risk assessment, diagnosis, and therapy. Detailed consideration is also paid to personalized health insurance in the new environment, the impact of personalized health care on the economics of health care, and the consequences for the global diagnostic market place and improved access to care. The changes in dental education required to produce dentists better equipped to participate in the new health care environment are examined, and the book concludes by considering key opportunities and challenges.




Pediatric Dentistry


Book Description

Pediatric Dentistry: A Clinical Approach, Third Edition provides a uniquely clear, comprehensive, and clinical approach to the dental treatment of children and adolescents. Offers systematic coverage of all clinical, scientific and social topics relating to pediatric dentistry Thoroughly revised and updated new edition, with an increased focus on evidence based care Includes three new chapters on genetics, child abuse and neglected children, and ethics Pedodontic endodontics is now covered by two chapters – one on primary teeth and one on young permanent teeth Features a companion website with interactive self-assessment questions




Dental Caries


Book Description

This book provides information to the readers starting with the history of oral hygiene manners, and modern oral hygiene practices. It continues with the prevalence and etiology of caries and remedy of caries through natural sources. Etiology of secondary caries in prosthetic restorations and the relationship between orthodontic treatment and caries is addressed. An update of early childhood caries is presented. The use of visual-tactile method, radiography and fluorescence in caries detection is given. The book finishes with methods used for the prevention of white spot lesions and management of caries.




Caries Excavation: Evolution of Treating Cavitated Carious Lesions


Book Description

Currently there is no reason, in most cases of cavitated caries lesions, to remove affected tissue. This book presents evidence-based research on the topic and provides assessments of diagnostic devices. It offers new insights into how a dentine carious cavity can be managed by either tissue removal or restoration. Methods for preserving dental tissue are presented and ample evidence highlights the need to seal with a quality restorative material. An update on how to conduct a randomized clinical trial is followed by a chapter on agreed upon terminology for supporting improved communication among oral health professionals around the world. This is a must-read for general practitioners, restorative specialists, dental students, and oral hygienists/therapists.