Fungal Genetics


Book Description

This is a concise guide to the combined use of classical and molecular methods for the genetic analysis and breeding of fungi. It presents basic concepts and experimental designs, and demonstrates the power of fungal genetics for applied research in biotechnology and phytopathology. Case studies of Saccharomyces cerevisiae, Candida albicans, Aspergillus niger, Neurospora crassa, Podospora anserina, Phytophthora infestans and others are included.




Genetics of Fungi


Book Description

The significance of genetics in biology today stems to a considerable extent from the knowledge which has been obtained through the use of fungi as experimental objects. As a result of their short generation time, their ease of culture under laboratory conditions, and the possibil ity of identifying the four products of meiosis through tetrad analysis, the fungi have proven themselves in many ways superior to the classic genetic experimental material such as Drosophila and maize. Because they permit investigation of genetic fine structure as well as biochemical analysis of the function of the genetic material, the fungi can be used, just as the bacteria and bacteriophages, for molecular biological research. Further, the fungi, because of their simple organi zation, are suitable for investigation of the genetic and physiological bases of morphogenesis and of extrachromosomal inheritance. This monograph is an attempt to summarize and interpret the results of genetic research on fungi. The reader should be reminded that review and interpretation of original research are inevitably influenced by the authors' own opinions. An understanding of the basic principles of genetics is assumed.




Oxford Textbook of Medical Mycology


Book Description

The Oxford Textbook of Medical Mycology is a comprehensive reference text which brings together the science and medicine of human fungal disease. Written by a leading group of international authors to bring a global expertise, it is divided into sections that deal with the principles of mycology, the organisms, a systems based approach to management, fungal disease in specific patient groups, diagnosis, and treatment. The detailed clinical chapters take account of recent international guidelines on the management of fungal disease. With chapters covering recent developments in taxonomy, fungal genetics and other 'omics', epidemiology, pathogenesis, and immunology, this textbook is well suited to aid both scientists and clinicians. The extensive illustrations, tables, and in-depth coverage of topics, including discussion of the non-infective aspects of allergic and toxin mediated fungal disease, are designed to aid the understanding of mechanisms and pathology, and extend the usual approach to fungal disease. This textbook is essential reading for microbiologists, research scientists, infectious diseases clinicians, respiratory physicians, and those managing immunocompromised patients. Part of the Oxford Textbook in Infectious Disease and Microbiology series, it is also a useful companion text for students and trainees looking to supplement mycology courses and microbiology training.




Fungal Genetics


Book Description

The chromosome theory as illustrated by the genetics of neurospora. Outline of the biology of fungi of genetic interest. The induction, isolation and characterization of mutants. Chromosome mapping-meiotic analysus. Genetic analysis based on mitosis. Polyploidy. The gene as a functional unit. The mechanism of genetic exchange and the fine structure of genes. The genetic control of metabolism. The genetic control of macromolecular structure. Systems of regulation of enzyme synthesis. The genetic control of sexual development. Extra-nuclear inheritance.




Essential Fungal Genetics


Book Description

Most genetics textbooks deal adequately with plant and animal genetics, but tend to neglect fungi. The authors have produced a book that will compensate for this imbalance. This book discusses the genetics of fungi in a way that is attractive and challenging, succinct yet comprehensive, sensitive to commercial and applied aspects, yet also theoretical, dealing with their genetics from molecules to individuals to population. This short text will be an ideal supplement to the established basic genetics texts or can be used as the sole text for an advanced course devoted to fungal genetics.




Fungal Genetics


Book Description

This is a concise guide to the combined use of classical and molecular methods for the genetic analysis and breeding of fungi. It presents basic concepts and experimental designs, and demonstrates the power of fungal genetics for applied research in biotechnology and phytopathology. Case studies of Saccharomyces cerevisiae, Candida albicans, Aspergillus niger, Neurospora crassa, Podospora anserina, Phytophthora infestans and others are included.




Fungi


Book Description

Fungi: Biology and Applications, Second Edition provides a comprehensive treatment of fungi, covering biochemistry, genetics and the medical and economic significance of these organisms at introductory level. With no prior knowledge of the subject assumed, the opening chapters offer a broad overview of the basics of fungal biology, in particular the physiology and genetics of fungi and also a new chapter on the application of genomics to fungi. Later chapters move on to include more detailed coverage of topics such as antibiotic and chemical commodities from fungi, new chapters on biotechnological use of fungal enzymes and fungal proteomics, and fungal diseases of humans, antifungal agents for use in human therapy and fungal pathogens of plants.




More Gene Manipulations in Fungi


Book Description

The original work, published in 1985, appeared at the first interface between classical fungal genetics and modern genetic engineering, reflecting the excitement of a young and promising discipline. Since then, molecular mycology has come of age. The entirely new More Gene Manipulations in Fungi reviews state-of-the-art research with an intent to inform the researcher about what can be achieved by studying fungal systems with the tools of molecular biology. This book is a current reference providing overviews as well as practical information. - Updates Bennett and Lasure's classic Gene Manipulations in Fungi published in 1985 - Describes fungi for the study of fundamental problems in biology and biochemistry - Explains both classical and molecular genetics for the study of fungi - Contains special appendixes on genetic analysis, growth media, and coding conventions - Demonstrates the progress of molecular mycology since the seminal paper published by Beadle and Tatum in 1941




Growing Fungus


Book Description

This book is about the growth and differentiation processes underlying the growth and differentia of filamentous fungi. The impetus for this work tion of fungi and that it provides the reader with stems from our perception that the coverage of adequate source references for further information. this highly diverse and important group of organ It is estimated conservatively that there are more isms has been neglected in recent years, despite than 1. 5 million species of fungi - more than five many significant advances in our understanding of times the number of vascular plants and second the underlying mechanisms of growth. This situ only in diversity to the insects. The extreme ation contrasts with the treatment of Saccharomyces diversity of form in the fungi has always been a cerevisiae, for example, which because of its ideal source of inspiration for mycologists. This book is properties for genetic analyses, has established concerned mainly with those systems that have itself as the model eukaryote for the analysis of the been well characterized from the biochemical, cell cycle, and basic studies of biochemical and physiological or genetic points of view. Although genetic regulation. This book does not deal with it has not been possible to illustrate the breadth of the detailed growth phYSiology of S.




Gene Manipulations in Fungi


Book Description

Gene Manipulations in Fungi combines a review of classical fungal genetics, contemporary research, and responsible speculation about the future. This book focuses on yeasts and molds; because yeast is the primary model system for eukaryotes and that there is an elegant research on molds. The applications of fungi, including their economic importance, are addressed. The book emphasizes the need for improved transformation systems, appropriate vectors, and broadly applicable selectable markers in this field of interest. This book will help stimulate the development of innovative approaches in this subject matter.