George Beadle, an Uncommon Farmer


Book Description

George Beadle was a towering scientific figure whose work from the 1930s to 1960 marked the transition from classical genetics to the molecular era. Among other distinctions, he made the pivotal, Nobel Prize–winning discovery with Edward Tatum that the role of genes is to specify proteins. From 1946 to 1960 he led the Caltech Biology Division, rebuilding it to a powerhouse in molecular biology, and afterwards became a successful President of the University of Chicago. This is the first biography of a giant of genetics, written by two of the field's most distinguished contributors, Paul Berg and Maxine Singer.




A Brief History of Genetics


Book Description

Biological inheritance, the passage of key characteristics down the generations, has always held mankind’s fascination. It is fundamental to the breeding of plants and animals with desirable traits. Genetics, the scientific study of inheritance, can be traced back to a particular set of simple but ground-breaking studies carried out 170 years ago. The awareness that numerous diseases are inherited gives this subject considerable medical importance. The progressive advances in genetics now bring us to the point where we have unravelled the entire human genome, and that of many other species. We can intervene very precisely with the genetic make-up of our agricultural crops and animals, and even ourselves. Genetics now enables us to understand cancer and develop novel protein medicines. It has also provided us with DNA fingerprinting for the solving of serious crime. This book explains for a lay readership how, where and when this powerful science emerged.




The Biology of Plants


Book Description

Plants are integral to human wellbeing, and many species have been domesticated for over ten thousand years. Evidence of plant scientific investigation and classification can be found in ancient texts from cultures around the world (Chinese, Indian, Greco-Roman, Muslim etc.), while early modern botany can be traced to the late 15th and early 16th centuries in Europe. During the past several decades plant biology has been revolutionized first by molecular biology and then by the genomic era. The model organism Arabidopsis thaliana has proved an invaluable tool for investigation into fundamental processes in plant biology, many of which share commonalities with animal biology. Plant-specific processes from reproduction to immunity and second messengers have also yielded to extensive investigation. With the genomes of more than thirty plant species now available and many more planned in the near future, the impact on our understanding of plant evolution and biology continues to grow. Our increased ability to engineer plant species to a variety of ends may provide novel solutions to ensure adequate and reliable food production and renewable energy even as climate change impacts our environment. The decision to focus the 2012 Symposium on plant science reflects the enormous research progress achieved in recent years, and is intended to provide a broad synthesis of the current state of the field, setting the stage for future discoveries and application. This is the first Symposium in this historic series focused exclusively on the botanical sciences. Plants are integral to human wellbeing, and many species have been domesticated for over ten thousand years. Evidence of plant scientific investigation and classification can be found in ancient texts from cultures around the world (Chinese, Indian, Greco-Roman, Muslim etc.), while early modern botany can be traced to the late 15th and early 16th centuries in Europe. During the past several decades plant biology has been revolutionized first by molecular biology and then by the genomic era. The model organism Arabidopsis thaliana has proved an invaluable tool for investigation into fundamental processes in plant biology, many of which share commonalities with animal biology. Plant-specific processes from reproduction to immunity and second messengers have also yielded to extensive investigation. With the genomes of more than thirty plant species now available and many more planned in the near future, the impact on our understanding of plant evolution and biology continues to grow. Our increased ability to engineer plant species to a variety of ends may provide novel solutions to ensure adequate and reliable food production and renewable energy even as climate change impacts our environment. The decision to focus the 2012 Symposium on plant science reflects the enormous research progress achieved in recent years, and is intended to provide a broad synthesis of the current state of the field, setting the stage for future discoveries and application. This is the first Symposium in this historic series focused exclusively on the botanical sciences.




The Emperor of All Maladies


Book Description

Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.







Science as a Way of Knowing


Book Description

This book makes Moore's wisdom available to students in a lively, richly illustrated account of the history and workings of life. Employing rhetoric strategies including case histories, hypotheses and deductions, and chronological narrative, it provides both a cultural history of biology and an introduction to the procedures and values of science.




The Youngest Science


Book Description

From the 1920s when he watched his father, a general practitioner who made housecalls and wrote his prescriptions in Latin, to his days in medical school and beyond, Lewis Thomas saw medicine evolve from an art into a sophisticated science. The Youngest Science is Dr. Thomas's account of his life in the medical profession and an inquiry into what medicine is all about--the youngest science, but one rich in possibility and promise. He chronicles his training in Boston and New York, his war career in the South Pacific, his most impassioned research projects, his work as an administrator in hospitals and medical schools, and even his experiences as a patient. Along the way, Thomas explores the complex relationships between research and practice, between words and meanings, between human error and human accomplishment, More than a magnificent autobiography, The Youngest Science is also a celebration and a warning--about the nature of medicine and about the future life of our planet.




The Disappearing Spoon


Book Description

From New York Times bestselling author Sam Kean comes incredible stories of science, history, finance, mythology, the arts, medicine, and more, as told by the Periodic Table. Why did Gandhi hate iodine (I, 53)? How did radium (Ra, 88) nearly ruin Marie Curie's reputation? And why is gallium (Ga, 31) the go-to element for laboratory pranksters? The Periodic Table is a crowning scientific achievement, but it's also a treasure trove of adventure, betrayal, and obsession. These fascinating tales follow every element on the table as they play out their parts in human history, and in the lives of the (frequently) mad scientists who discovered them. The Disappearing Spoon masterfully fuses science with the classic lore of invention, investigation, and discovery -- from the Big Bang through the end of time. Though solid at room temperature, gallium is a moldable metal that melts at 84 degrees Fahrenheit. A classic science prank is to mold gallium spoons, serve them with tea, and watch guests recoil as their utensils disappear.










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