Author : Donald Mackay
Publisher : CRC Press
Page : 4196 pages
File Size : 26,50 MB
Release : 2006-03-14
Category : Science
ISBN : 1420044397
CHOICE Award WinnerTransport and transformation processes are key for determining how humans and other organisms are exposed to chemicals. These processes are largely controlled by the chemicals' physical-chemical properties. This new edition of the Handbook of Physical-Chemical Properties and Environmental Fate for Organic Chemicals is a comprehen
Author : Bill Acree
Publisher : BoD – Books on Demand
Page : 532 pages
File Size : 28,71 MB
Release : 2012-02-10
Category : Medical
ISBN : 9535100041
Modern drug design and testing involves experimental in vivo and in vitro measurement of the drug candidate's ADMET (adsorption, distribution, metabolism, elimination and toxicity) properties in the early stages of drug discovery. Only a small percentage of the proposed drug candidates receive government approval and reach the market place. Unfavorable pharmacokinetic properties, poor bioavailability and efficacy, low solubility, adverse side effects and toxicity concerns account for many of the drug failures encountered in the pharmaceutical industry. Authors from several countries have contributed chapters detailing regulatory policies, pharmaceutical concerns and clinical practices in their respective countries with the expectation that the open exchange of scientific results and ideas presented in this book will lead to improved pharmaceutical products.
Author : Katherine A. Sloman
Publisher : Gulf Professional Publishing
Page : 508 pages
File Size : 19,26 MB
Release : 2005-12-13
Category : Medical
ISBN : 9780123504487
Traditionally, behaviour and physiology have been considered two separate fields of biology with the majority of available literature focusing on one or the other. Recently the need for a multidisciplinary approach to these topics has been realised, highlighted by some of the sessions to be held at the 2003 annual meeting of the Society for Integrative and Comparative Biology such as 'regulation of behaviour' and 'mechanisms of behaviour'. The proposed volume aims to bring together these disciplines in a comprehensive review of the available literature. Fish Physiology: Behaviour and Physiology of Fish will be novel in actively bridging these two areas of fish biology together and considering them as inextricably linked. The progression of chapters focuses on different aspects of the life history of a fish, from predator avoidance through to reproduction, each written by scientists currently bridging the gap between behaviour and physiology in their own specialised subdiscipline. Multidisciplinary and integrative research in fish biology Written by internationally recognized researchers Encompasses the whole life span of fish A wide variety of inter-related topics presented in a cohesive format
Author : C.J. van Leeuwen
Publisher : Springer Science & Business Media
Page : 706 pages
File Size : 11,90 MB
Release : 2007-09-18
Category : Science
ISBN : 1402061013
At last – a second edition of this hugely important text that reflects the progress and experience gained in the last decade and aims at providing background and training material for a new generation of risk assessors. The authors offer an introduction to risk assessment of chemicals as well as basic background information on sources, emissions, distribution and fate processes for the estimation of exposure of plant and animal species in the environment and humans exposed via the environment, consumer products, and at the workplace. The coverage describes the basic principles and methods of risk assessment within their legislative frameworks (EU, USA, Japan and Canada).
Author : Gary M. Rand
Publisher : CRC Press
Page : 1152 pages
File Size : 15,31 MB
Release : 2020-08-06
Category : Science
ISBN : 100016294X
This text is divided into three parts. The first part describes basic toxicological concepts and methodologies used in aquatic toxicity testing, including the philosophies underlying testing strategies now required to meet and support regulatory standards. The second part of the book discusses various factors that affect transport, transformation, ultimate distribution, and accumulation of chemicals in the aquatic environment, along with the use of modelling to predict fate.; The final section of the book reviews types of effects or endpoints evaluated in field studies and the use of structure-activity relationships in aquatic toxicology to predict biological activity and physio-chemical properties of a chemical. This section also contains an extensive background of environmental legislation in the USA and within the European Community, and an introduction to hazard/risk assessment with case studies.
Author :
Publisher :
Page : 928 pages
File Size : 42,28 MB
Release : 2003
Category : Environmental chemistry
ISBN :
Author : Ian J. Tinsley
Publisher : John Wiley & Sons
Page : 419 pages
File Size : 47,16 MB
Release : 2004-06-11
Category : Science
ISBN : 0471095257
Chemical Concepts in Pollutant Behavior demonstrates how the properties of a chemical determine its fate and distribution in the environment. Over the past thirty years the author has worked with colleagues on addressing problems associated with chemicals, particularly pesticides, and it has become evident how important a chemical perspective can be in understanding and minimizing these problems. Now in a newly updated second edition, this accessible text requires only a basic understanding of chemistry. Classroom tested, it is an excellent resource for students and professionals working in environmental science, toxicology, chemistry, and engineering, as well as ecology, public health, agriculture, and forestry.
Author : Vladimir Pliska
Publisher : John Wiley & Sons
Page : 463 pages
File Size : 30,17 MB
Release : 2008-09-26
Category : Science
ISBN : 3527614982
In keeping with the outstanding importance of lipophilicity in biosciences, this volume examines all its facets in more than twenty contributions from leading experts. It offers a thorough and highly topical survey of this rapidly developing field of research. Color plates demonstrating structural aspects, a vast number of references, and the straightforward presentation of the material make this volume a invaluable tool for all researchers involved in drug design or in the investigation of drug action.
Author : Werner G. K. Backhaus
Publisher : Walter de Gruyter
Page : 361 pages
File Size : 18,17 MB
Release : 2011-06-24
Category : Science
ISBN : 3110806983
Author : David Mostofsky
Publisher : Elsevier
Page : 408 pages
File Size : 21,19 MB
Release : 2012-12-02
Category : Science
ISBN : 0323151736
The Behavior of Fish and Other Aquatic Animals provides a comprehensive discussion of the behavior of fish and other aquatic animals. It aims to fulfill the need for published materials that can responsibly depict the status quo of existing knowledge, and that can serve to educate the scientist seeking an organized presentation focused on biobehavioral issues and techniques. The book begins by exploring symbiotic relationships in fishes that range from broad multispecific types that have little or no intimacy between symbionts to intimate mutualistic relationships. It then presents studies on the feasibility of using teleost fish as subjects in behavioral toxicology experiments; the visual behavior of fishes; the role of the teleost telencephalon in behavior; and the auditory systems of fishes. The remaining chapters cover the behavior of turtles in land, sea, and fresh waters; visually guided behavior in turtles; the gas bubble disease of fish; and the advantages and limitations of acoustic telemetry, which has been used to obtain data from animals ranging in size from hatchling sea turtles to large tuna and sharks.
