Guidance on Pfas Exposure, Testing, and Clinical Follow-Up


Book Description

In thousands of communities across the United States, drinking water is contaminated with chemicals known as perfluoroalkyl and polyfluoroalkyl substances (PFAS). PFAS are used in a wide range of products, such as non-stick cookware, water and stain repellent fabrics, and fire-fighting foam, because they have properties that repel oil and water, reduce friction, and resist temperature changes. PFAS can leak into the environment where they are made, used, disposed of, or spilled. PFAS exposure has been linked to a number of adverse health effects including certain cancers, thyroid dysfunction, changes in cholesterol, and small reductions in birth weight. This report recommends that the Centers for Disease Control and Prevention (CDC) update its clinical guidance to advise clinicians to offer PFAS blood testing to patients who are likely to have a history of elevated exposure, such as those with occupational exposures or those who live in areas known to be contaminated. If testing reveals PFAS levels associated with an increased risk of adverse effects, patients should receive regular screenings and monitoring for these and other health impacts. Guidance on PFAS Exposure, Testing, and Clinical Follow-Up recommends that the CDC, Agency for Toxic Substances and Disease Registry (ATSDR), and public health departments support clinicians by creating educational materials on PFAS exposure, potential health effects, the limitations of testing, and the benefits and harms of testing.




Human Biomonitoring for Environmental Chemicals


Book Description

Biomonitoring—a method for measuring amounts of toxic chemicals in human tissues—is a valuable tool for studying potentially harmful environmental chemicals. Biomonitoring data have been used to confirm exposures to chemicals and validate public health policies. For example, population biomonitoring data showing high blood lead concentrations resulted in the U.S. Environmental Protection Agency's (EPA's) regulatory reduction of lead in gasoline; biomonitoring data confirmed a resultant drop in blood lead concentrations. Despite recent advances, the science needed to understand the implications of the biomonitoring data for human health is still in its nascent stages. Use of the data also raises communication and ethical challenges. In response to a congressional request, EPA asked the National Research Council to address those challenges in an independent study. Human Biomonitoring for Environmental Chemicals provides a framework for improving the use of biomonitoring data including developing and using biomarkers (measures of exposure), research to improve the interpretation of data, ways to communicate findings to the public, and a review of ethical issues.




Toward a PFAS-free Future


Book Description

Perfluoroalkyl and polyfluoroalkyl substances (PFASs) are extensively used in consumer products, despite their high persistence and other hazards. The risks posed by this chemical class to human health and the environment, which are increasingly becoming understood, have triggered regulation and policy changes. However, safer alternatives to these technically effective materials and methods to discover and use those alternatives are still under development. Remediation of PFAS contaminated sites will not solve the growing worldwide pollution, but substitution with safer substances at the formulation and manufacturing phases will at least abate the flow of PFASs into our bodies and environment. Introducing safer alternatives to some of the PFASs of concern used in select industry sectors, this book informs the reader about the processes of chemical hazard and alternatives assessment that can foster innovation. It is a valuable resource for both green chemists and industrial chemists interested in how they can make their products safer without compromising on function.




Blood


Book Description

The galvanizing new book from Dr. Jen Gunter, #1 bestselling author of The Vagina Bible and The Menopause Manifesto, dispels the shame, mythology, and misinformation around menstruation with scientific facts, medical expertise, and a fierce feminist perspective. Most of us know about as much about how the uterus and ovaries function as we do about how the liver works. Add in societal shame around the menstrual cycle and it’s not surprising that misinformation is widespread. But, as women’s health advocate and trusted OB-GYN Dr. Jen Gunter writes, “you don’t have to think about your liver 5 days a month for 30 years, so I’d argue people should know more about the uterus." Enter Blood. In her new book, Dr. Gunter offers a clear, no-nonsense guide to reproductive anatomy and answers all the questions you never knew you had about menstrual bleeding—for example, where does the blood come from? And where does it go if you miss a period? Why do we even menstruate in the first place? With her expertise and trademark wit, Dr. Gunter debunks myths and challenges patriarchal attitudes toward this natural bodily process, shedding light on: The endometrium's fascinating connection to the immune system The brain-ovary connection Legitimate menstrual products, and the facts behind toxic shock syndrome Irregular, heavy, and breakthrough bleeding Period pain Endometriosis Polycystic Ovary Syndrome Hormonal contraception, menstrual tracking, and FAM (fertility awareness methods) Abortion as menstrual management And much more. Surprising, funny, and fact-filled, Blood is an essential and empowering resource from the doctor who "takes the mystery out of women’s health and replaces it with evidence-informed concrete recommendations." (Lori Brotto, Canada Research Chair in Women's Sexual Health)




Yen & Jaffe's Reproductive Endocrinology - E-Book


Book Description

For over 40 years, Yen & Jaffe's Reproductive Endocrinology has been the gold standard text of both basic science and clinical practice of the full range of female and male reproductive disorders. The fully revised 9th Edition continues this tradition of excellence with complete coverage, including up-to-date information on impaired fertility, infertility, recurrent pregnancy loss, problems of sexual development, menstrual disturbances, fibroids, endometriosis, female and male reproductive aging, fertility preservation, assisted reproduction technologies including ovarian stimulation and ovulation induction, transgender hormonal treatment, contraception, and more. An outstanding editorial board and other global experts in the field share their knowledge and expertise to keep you abreast of current science and practice in endocrinology. - Includes new chapters on Meiosis, Fertilization and Embryo Development; Recurrent Pregnancy Loss; Uterus Transplantation; Mitochondrial Transplantation and Gene Editing; and Germs Cells Developed In Vitro. - Provides extensively revised information on contemporary practices in assisted reproduction, fertility preservation, and ovulation induction. - Provides an online video library that highlights surgical procedures, diagnostic imaging, and functional ultrasound imaging. - Adds three new members to the exceptional editorial team: Drs. Anuja Dokras, Carmen J. Williams, and Zev Williams. - Features full-color, high-quality illustrations that clearly depict basic anatomic structures, endocrine processes, and cell function and dysfunction. - Includes bulleted lists under major headings in each chapter for quick, at-a-glance summaries of every section. - Lists Top References at the end of each chapter that distill the most important references for research underpinnings, to complement the complete online reference list. - An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.




Use and Potential Impacts of AFFF Containing PFASs at Airports


Book Description

TRB's Airport Cooperative Research Program (ACRP) Research Report 173: Use and Potential Impacts of AFFF Containing PFASs at Airports explores the potential environmental and health impacts of per- and polyfluoroalkyl substances (PFASs) typically found in aqueous film-forming foams (AFFFs). The report describes methods that can be used to identify areas of potential concern at an airport and ways to implement management and remediation practices.




Textbook of Children's Environmental Health


Book Description

With new and updated content on biodiversity and chemicals in food, Textbook of Children's Environmental Health, Second Edition remains the quintessential textbook for the study of the environmental hazards that cause disease in childre







Forever Chemicals


Book Description

Forever Chemicals: Environmental, Economic, and Social Equity Concerns with PFAS in the Environment provides the reader with an understanding of the complex and interwoven issues associated with per- and polyfluorinated substances (PFAS) in our environment. The chapters provide in-depth perspective into various issues, including health, regulation, detection, clean-up strategies and technologies, and more. Taken together or as the reader’s interests lead them, the variety of topics covered in the book present a balanced perspective on this complex topic. It will address the current state of PFAS and where indicators are pointing for future developments. The book is also a deeper investigation of the regulatory challenges, analytical hurdles, and toxicological progress to date for the suite of PFAS chemicals. Features Explains the trends that will affect future policy and regulatory decisions Looks holistically at 4000+ PFAS chemicals Includes PFAS risk assessments at contaminated sites and biomonitoring insights Provides in-depth discussions on remediation technologies Illustrates quality and diversified content Provides a balanced perspective on this complex topic




Prenatal and Postnatal Care


Book Description

Prenatal and Postnatal Care Situate pregnancy in the emotional and physical life of the whole person with this bestselling guide Prenatal and postnatal care are important and dynamic areas in healthcare research and practice. The needs of the childbearing person before and after birth are complex and intensely personal, combining significant physiological impact with broader emotional needs. In order to supply optimal care, providers must account not only for physiological factors, but also for cultural, social, experiential, and psychological ones. Prenatal and Postnatal Care takes a holistic, person-centered approach to prenatal and postnatal care. Emphasizing the pregnant person and their unique needs, this book presents prenatal and postnatal care as foundational care for a healthy start to family life. This accessible, comprehensive book provides unique knowledge and skills to practitioners so that they can make a positive difference to the people they serve. Readers of the third edition of Prenatal and Postnatal Care will also find: New chapters covering health equity, ethics in perinatal care, exercise, and more All chapters updated to reflect evidence concerning health disparities and inequities Concrete ways for clinicians to disrupt the systems of harm and exclusion that can mediate care at every level Prenatal and Postnatal Care is essential for midwives, nurse practitioners, physician assistants, and other healthcare providers who work with childbearing people.