Author : Nicos Nicola
Publisher : Sambrook and Tooze Publication at Oxford University Press
Page : 292 pages
File Size : 27,75 MB
Release : 1994
Category : History
ISBN :
The number of cytokines and related growth factors has increased dramatically in recent years to several dozen. This text provides a succinct reference manual for all known cytokines, growth factors, interleukins and lymphokines as well as their receptors.
Author : Zlatko Dembic
Publisher : Academic Press
Page : 323 pages
File Size : 23,20 MB
Release : 2015-05-23
Category : Medical
ISBN : 0124200109
The Cytokines of the Immune System catalogs cytokines and links them to physiology and pathology, providing a welcome and hugely timely tool for scientists in all related fields. In cataloguing cytokines, it lists their potential for therapeutic use, links them to disease treatments needing further research and development, and shows their utility for learning about the immune system. This book offers a new approach in the study of cytokines by combining detailed guidebook-style cytokine description, disease linking, and presentation of immunologic roles. - Supplies new ideas for basic and clinical research - Provides cytokine descriptions in a guidebook-style, cataloging the origins, structures, functions, receptors, disease-linkage, and therapeutic potentials - Offers a textbook-style view on the immune system with the immunologic role of each cytokine
Author : Ralph A. Bradshaw
Publisher : Academic Press
Page : 2560 pages
File Size : 18,24 MB
Release : 2003-12-02
Category : Science
ISBN : 0080533574
The Handbook of Cell Signaling is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The subject matter has been divided into five main parts (each of which is headed by a recognized expert in the field):* Initiation: Extracellular and Membrane Events* Transmission: Effectors and Cytosolic Events * Nuclear Responses: Gene Expression and Translation* Events in Intracellular Compartments* Cell-Cell and Cell-Matrix Interactions Covered in extensive detail, these areas will appeal to a broad, cross-disciplinary audience interested in the structure, biochemistry, molecular biology and pathology of cellular effectors. Tabular and well-illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field.Tabular and well illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field!* Contains approximately 470 articles* Provides well-organized sections on each essential area in signaling* Includes discussion on everything from ligand/receptor interactions to organ/organism responses* Extremely user-friendly
Author : Constantin A. Bona
Publisher : CRC Press
Page : 864 pages
File Size : 12,37 MB
Release : 2003-09-02
Category : Science
ISBN : 0203305132
The field of cytokine research is expanding at a rapid pace Contributions from the major leading groups in the world on the structure and biological properties of cytokine and cytokine receptors, as well as integrated reviews on cytokines in various physiological and pathological conditions were presented in three issues of International Reviews of Immunology This collection of articles provided a unique source of information However, important discoveries are emerging very rapidly and some of the reviews written in 1997 are already outdated In this book, the editors assemble reviews that have been updated by their authors to include all the recent publications and unpublished data from the authors' laboratories This volume should serve as an excellent reference source for all those concerned by the multiple faces of cytokines in basic research and in the clinic
Author : C. Bondy
Publisher : Elsevier
Page : 449 pages
File Size : 17,13 MB
Release : 1997-04-18
Category : Science
ISBN : 0080532640
Progress in molecular technology in recent years has caused an amazing growth of information about intercellular peptide messengers and their receptors. The number of characterized interleukins for example numbered just three six years ago and now there are at least 16. In addition, the number of described neutrophic peptides is around 30 and the number of receptors is ever increasing. Because many of these new peptide ligands and receptors were identified by "reverse genetic" techniques the understanding of their biological roles falls behind the knowledge of their molecular structures. However a new strain of functional studies has begun and animal models are developed allowing for further research into the biological roles of these messenger peptides and their receptors. Cytokines, the theme of this volume, describes a group of proteins identified primarily within the immune and hematopoietic systems. As many cytokines as possible are included along with their receptors providing the reader with a guide to an ever-changing field of scientific research.
Author : Robert Dantzer
Publisher : Springer Science & Business Media
Page : 335 pages
File Size : 20,74 MB
Release : 2007-11-23
Category : Medical
ISBN : 058537970X
Cytokines had been characterized in the early eighties as communication mole cules between immune cells, and between immunocytes and other peripheral cells, such as fibroblasts and endothelial cells. They play a key role in the regulation of the immune response and the coordination of the host response to infection. Based on these biological properties, nobody would have predicted that one decade later cytokines would burst upon neurosciences and permeate into several avenues of current research. In neurology, the connection between cytokines and inflammation, and the demonstration of a pivotal role of some of these molecules in cell death by apoptosis, prompted the investigation of their involvement in several neurological diseases involving an inflammatory component, including multiple sclerosis, brain trauma, stroke, and Alzheimer's disease. This movement started in the late eighties, and the corresponding field of research, known as neuroimmunology, is presently booming. In psychiatry, however, the relationship between cytokines and mental disorders was much less evident and took longer to materialize. The first indication that cytokines might be involved in psychopathology came from cancerology and internal medicine.
Author : Ivan Maurice Roitt
Publisher :
Page : 244 pages
File Size : 29,79 MB
Release : 1971
Category : Immunity
ISBN :
Author : Rino Rappuoli
Publisher : OUP Oxford
Page : 278 pages
File Size : 17,86 MB
Release : 1997-05-29
Category : Medical
ISBN : 019154728X
Many bacteria, animals, and plants produce toxins that can prove lethal to other organisms. Toxins are a form of "biological warfare" that helps their producer to survive and so confer an evolutionary advantage. They display an extraordinary range of complexity, from the formic acid provided by ants to bacterial proteins composed of thousands of amino acids. This Guidebook considers the more complex protein and peptide toxins and groups them according to their mode of action. Topics covered include: membrane-permeabilizing toxins; toxins affecting signal transduction and protein synthesis; cytoskeleton-affecting toxins; toxins affecting the immune and inflammatory response. This class of biomolecules will be of interest to a wide range of researchers in cell biology, neuroscience, and toxicology.
Author : David Wild
Publisher : Elsevier
Page : 968 pages
File Size : 19,85 MB
Release : 2005-06-20
Category : Medical
ISBN : 9780080445267
Containing updated and new information on advanced technology - including micro and nanoscale immunoassays - this text provides a mix of practical information coupled with a review of clincal applications and practical examples.
Author :
Publisher : Academic Press
Page : 330 pages
File Size : 37,81 MB
Release : 1998-10-12
Category : Medical
ISBN : 0080582257
Our most complete understanding of hormone receptor signaling may be exemplified in a family of hormones and receptors known as the cytokine superfamily. This volume is devoted to describing members of this hormone/receptor family from their molecular structures to their physiological effects. These hormones are not only biologically fascinating, but are also tremendously useful medicines.The first three chapters review the basic events in binding and signaling. The remaining papers present the cellular biology and physiological processes controlled by these hormones and receptors.
