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Final Report of the National Academies' Human Embryonic Stem Cell Research Advisory Committee and 2010 Amendments to the National Academies' Guidelines for Human Embryonic Stem Cell Research

Author : National Research Council

Publisher : National Academies Press

Page : 59 pages

File Size : 13,16 MB

Release : 2010-07-13

Category : Medical

ISBN : 0309158354

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Book Description

In 2005, the National Academies released the book, Guidelines for Human Embryonic Stem Cell Research, which offered a common set of ethical standards for a field that, due to the absence of comprehensive federal funding, was lacking national standards for research. In order to keep the Guidelines up to date, given the rapid pace of scientific and policy developments in the field of stem cell research, the Human Embryonic Stem Cell Research Advisory Committee was established in 2006 with support from The Ellison Medical Foundation, The Greenwall Foundation, and the Howard Hughes Medical Institute. As it did in 2007 and 2008, the Committee identified issues that warranted revision, and this book addresses those issues in a third and final set of amendments. Specifically, this book sets out an updated version of the National Academies' Guidelines, one that takes into account the new, expanded role of the NIH in overseeing hES cell research. It also identifies those avenues of continuing National Academies' involvement deemed most valuable by the research community and other significant stakeholders.



Stem Cells and the Future of Regenerative Medicine

Author : Institute of Medicine

Publisher : National Academies Press

Page : 112 pages

File Size : 10,28 MB

Release : 2002-01-25

Category : Science

ISBN : 0309170427

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Book Description

Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.



Human Embryonic Stem Cells

Author : Arlene Chiu

Publisher : Springer Science & Business Media

Page : 488 pages

File Size : 25,62 MB

Release : 2003-08

Category : Science

ISBN :

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Book Description

A discussion of all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from trauma. On the practical side, the topics range from the problems of deriving human embryonic stem cells and driving their differentiation along specific lineages, regulating their development into mature cells, and bringing stem cell therapy to clinical trials. Regulatory issues are addressed in discussions of the ethical debate surrounding the derivation of human embryonic stem cells and the current policies governing their use in the United States and abroad, including the rules and conditions regulating federal funding and questions of intellectual property.



The Ethics of Embryonic Stem Cell Research

Author : Katrien Devolder

Publisher : OUP Oxford

Page : 211 pages

File Size : 27,27 MB

Release : 2015-01-22

Category : Philosophy

ISBN : 0191036234

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Book Description

Embryonic stem cell research holds unique promise for developing therapies for currently incurable diseases and conditions, and for important biomedical research. However, the process through which embryonic stem cells are obtained involves the destruction of early human embryos. Katrien Devolder focuses on the tension between the popular view that an embryo should never be deliberately harmed or destroyed, and the view that embryonic stem cell research, because of its enormous promise, must go forward. She provides an in-depth ethical analysis of the major philosophical and political attempts to resolve this tension. One such attempt involves the development of a middle ground position, which accepts only types or aspects of embryonic stem cell research deemed compatible with the view that the embryo has a significant moral status. An example is the position that it can be permissible to derive stem cells from embryos left over from in vitro fertilisation but not from embryos created for research. Others have advocated a technical solution. Several techniques have been proposed for deriving embryonic stem cells, or their functional equivalents, without harming embryos. An example is the induced pluripotent stem cell technique. Through highlighting inconsistencies in the arguments for these positions, Devolder argues that the central tension in the embryonic stem cell debate remains unresolved. This conclusion has important implications for the stem cell debate, as well as for policies inspired by this debate.



Human Genome Editing

Author : National Academies of Sciences, Engineering, and Medicine

Publisher : National Academies Press

Page : 329 pages

File Size : 42,7 MB

Release : 2017-08-13

Category : Medical

ISBN : 0309452880

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Book Description

Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.



Contested Cells

Author : Benjamin J. Capps

Publisher : World Scientific

Page : 517 pages

File Size : 20,88 MB

Release : 2010

Category : Medical

ISBN : 1848164378

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Book Description

This book represents the coming together of a number of internationally renowned scholars from science, philosophy, law and social science. Each author presents a distinctive and critical account of the current ethical, social and jurisprudential issues concerning stem cell science: together covering both its research beginnings, and the future translation into the clinical setting. Original to this volume is an emphasis on the inter-state implications of developments in stem cell science from the perspective of a truly global collaboration of leading authors. Academics and policy-makers will find it an invaluable contribution to the socio-political and ethical discourse of stem cell science. Contributions from a team of leading academic experts Covers a wide array of disciplines: with original contributions focusing on the technological, legal, social and ethical aspects of stem cell science A unique collection of international perspectives on developments in stem cell science Book jacket.



Bioethics and the Future of Stem Cell Research

Author : Insoo Hyun

Publisher : Cambridge University Press

Page : 239 pages

File Size : 48,58 MB

Release : 2013-06-24

Category : Medical

ISBN : 0521768691

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Book Description

This book provides a sophisticated yet accessible account of emerging trends in stem cell research and their accompanying ethical issues.



Scientific and Medical Aspects of Human Reproductive Cloning

Author : National Research Council

Publisher : National Academies Press

Page : 295 pages

File Size : 30,61 MB

Release : 2002-06-17

Category : Science

ISBN : 0309076374

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Book Description

Human reproductive cloning is an assisted reproductive technology that would be carried out with the goal of creating a newborn genetically identical to another human being. It is currently the subject of much debate around the world, involving a variety of ethical, religious, societal, scientific, and medical issues. Scientific and Medical Aspects of Human Reproductive Cloning considers the scientific and medical sides of this issue, plus ethical issues that pertain to human-subjects research. Based on experience with reproductive cloning in animals, the report concludes that human reproductive cloning would be dangerous for the woman, fetus, and newborn, and is likely to fail. The study panel did not address the issue of whether human reproductive cloning, even if it were found to be medically safe, would beâ€"or would not beâ€"acceptable to individuals or society.





Report of the Committee of Inquiry Into Human Fertilisation and Embryology

Author : Great Britain. Committee of Inquiry into Human Fertilisation and Embryology

Publisher :

Page : 130 pages

File Size : 10,49 MB

Release : 1984

Category : Artificial insemination

ISBN :

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Book Description

The Report of the Committee of Inquiry into Human Fertilisation and Embryology (1984) (the “Warnock report”) set out the regulatory framework and ethical consensus that still govern human fertilisation today. It was the work of a committee chaired by Warnock, which had spent two years painstakingly sifting evidence from doctors, scientists, anti-abortion groups, faith leaders, and many more.The inquiry was prompted by new in vitro fertilisation (IVF) techniques, which led to the birth of the first “test tube” baby, Louise Brown, in 1978. Some were uneasy about the ethics of IVF, and by 1980 MPs were lobbying for an inquiry.