Hair Research


Book Description

Several years ago a friendly looking young man walked into my office at the University Department of Dermatology in Cologne, introduced himself as a diplomate chemist, executive member of a family-owned, rather small German company manufacturing hair care products, and proposed to me straight forward to organize an international meeting on hair research. In view of the large number of new developments in the field something like this should be done after all, he said; he also promised to provide financial support. Such a meeting should be on the highest possible level, I said; and he agreed. I took the challenge and my visitor kept his promise. Three years later the First International Hair Congress was organized at the sophisticated new Congress Center in Hamburg, in which 630 participants from 36 countries were registered. After three and a half days of formal sessions, informal discussions, workshops and poster presentations our unanimous feeling was that this has been a most successful meeting. The young chemist was right. The idea was excellent. The growth and presence of hair and its distribution over the human body as a cosmetic attribute has become during the last two decades a matter of tremendous emotional significance. Hair can be rather easily formed according to one's sence of style, representing his personal image and his social feeling. If it becomes unacceptable or out of fashion, the hair style can be easily changed; the hair regrows as a biological requisite, without any additional cost.




Trends in Human Hair Growth and Alopecia Research


Book Description

It is now thirty years since William Montagna and Richard Ellis edited 'The Biology of Hair Growth". In his introduction, Stephen Rothman, of the University of Chicago, USA and one of the driving forces behind research on skin at the time, wrote: 'The pilary system is a perfect micr9cosmic structure. In this microcos mos we find birth, development, ageing and death, activity and rest, color for mation and decolorification, greasiness and dryness, infection and sterilization, hypertrophy and atrophy, Qenign tumours and malignant ones." He foresaw the human pilary system as a model for the study of a multitude of human diseases including ageing and cancer. It was not, how ever, until the seventies that the development of micro-biochemical tech niques indeed allowed the use of the human hair follicle as a convenient biopsy tissue for Biomedical Research in general. Measurement of enzyme activities, and important co-factors, and culturing of cells from single follicles all became possible. In the eighties dermal papilla cells were grown in cul ture and this opened the way to study hair differentiation in vitro. Studying hair differentiation is, in fact, studying growth regulation and it is this aspect that by far transcends the importance of studying hair growth itself. Let us not forget that metastatic prostate cancer is treated with the same drug -cyproterone acetate -that is used for the treatment of alopecia and hirsutism in women.







Dermatopharmacology of Topical Preparations


Book Description

Proof of the efficacy of dermatological products is a prerequisite for clinical testing and registration. Now, efficacy claims for cosmetics must be equally substantiated. This book provides a concise, practical but comprehensive overview of experimental models used to screen, develop and select dermatological and cosmetic formulations. The authors are recognized specialists in their field and use a standardized approach to the projects facilitating the reading for the stressed scientist, for the R+D managers general view as well as for the beginners in the field.




Alopecia


Book Description

Get a quick, expert overview of alopecia with this concise, practical resource. Dr. Mariya Miteva covers high-interest clinical topics including hair cosmeceuticals, new medications in clinical trials, off-label treatment technologies, and much more. It's an ideal resource for dermatologists, dermatopathologists, students, fellows, and researchers interested in hair loss. - Presents rich visual information combined with expert opinions from the most renowned hair experts practicing today. - Covers basic knowledge on healthy hair, hair pathology, and hair and scalp dermatoscopy (trichoscopy). - Contains focused yet complete coverage of non-scarring alopecia, primary lymphocytic cicatricial alopecia, primary neutrophilic ciatricial alopecia, hair loss management, and miscellaneous hair disorders such as hair loss in children, hair and scalp infections, hair changes due to drugs, and more. - Consolidates today's available information and experience in this important area into one convenient resource.







Experimental Animal Models of Human Diseases


Book Description

The world has recorded losses in terms of human life as well as extensive time spent in experimentation with development of new drugs, elucidation of disease mechanism(s), and therapeutic agent discovery. Ethical and legal issues cojoin in slowing down scientific discoveries in medicine and biology. The past two (2) decades, therefore, have seen tremendous attempts that largely are successful in developing animal models with the characteristics of mimicking, approximating, or expressing transplanted human organs/tissues. These models or rather approaches seem to be fast, cost-effective, and easy to maintain compared to primates. This book is a collection of expert essays on animal models of human diseases of global interest. A visible objective of the book is to provide real-time experimental approach to scientists, clinicians, ethicists, medicolegal/medical jurisprudence workers, immunologists, postgraduate students, and vaccinologists and informative and multidisciplinary approach for the identification of new therapeutic targets and biomarkers using animal models as well as investigating the pathogenesis and therapeutic strategies of human diseases. An increased understanding of the genetic, molecular, and cellular mechanisms responsible for the development of human diseases has laid out the foundation for the development of rational therapies mainly with animal models.




Forensic Examination of Hair


Book Description

The examination of human hairs in the forensic science setting is a highly specialist forensic discipline. To date the topic has not been covered in a single volume in which all aspects of hair examination are brought together. In this volume an international group of authors have dealt with all aspects of the examination of human hair. The volume opens with the basic foundation accidence covering the physiology, growth and structure of hair. Forensic specific aspects of hair structure are then dealt with and a protocol for examination is presented. The remaining chapters deal with non microscopy approaches to hair examination covering historical and contemporary knowledge. These chapters include biochemical approaches to hair examination,




Ebony


Book Description

EBONY is the flagship magazine of Johnson Publishing. Founded in 1945 by John H. Johnson, it still maintains the highest global circulation of any African American-focused magazine.




Ebony


Book Description

EBONY is the flagship magazine of Johnson Publishing. Founded in 1945 by John H. Johnson, it still maintains the highest global circulation of any African American-focused magazine.