High Calorie Diet and the Human Brain


Book Description

The purpose of this monograph is to present readers with a comprehensive and cutting edge description of neurochemical effects of diet (beneficial and harmful effects) in normal human brain and to discuss how present day diet promotes pathogenesis of stroke, AD, PD, and depression in a manner that is useful not only to students and teachers but also to researchers, dietitians, nutritionists and physicians. A diet in sufficient amount and appropriate macronutrients is essential for optimal health of human body tissues. In brain, over-nutrition, particularly with high-calorie diet, not only alters cellular homeostasis, but also results in changes in the intensity of signal transduction processes in reward centers of the brain resulting in food addiction. Over-nutrition produces detrimental effects on human health in general and brain health in particular because it chronically increases the systemic and brain inflammation and oxidative stress along with induction of insulin resistance and leptin resistance in the brain as well as visceral organs. Onset of chronic inflammation and oxidative stress not only leads to obesity and heart disease, but also promotes type II diabetes and metabolic syndrome, which are risk factors for both acute neural trauma (stroke) and chronic age-related neurodegenerative and neuropsychological disorders, such as Alzheimer disease (AD), Parkinson disease (PD) and depression.




Fat Detection


Book Description

Presents the State-of-the-Art in Fat Taste TransductionA bite of cheese, a few potato chips, a delectable piece of bacon - a small taste of high-fat foods often draws you back for more. But why are fatty foods so appealing? Why do we crave them? Fat Detection: Taste, Texture, and Post Ingestive Effects covers the many factors responsible for the se




The Hungry Brain


Book Description

A Publishers Weekly Best Book of the Year From an obesity and neuroscience researcher with a knack for engaging, humorous storytelling, The Hungry Brain uses cutting-edge science to answer the questions: why do we overeat, and what can we do about it? No one wants to overeat. And certainly no one wants to overeat for years, become overweight, and end up with a high risk of diabetes or heart disease--yet two thirds of Americans do precisely that. Even though we know better, we often eat too much. Why does our behavior betray our own intentions to be lean and healthy? The problem, argues obesity and neuroscience researcher Stephan J. Guyenet, is not necessarily a lack of willpower or an incorrect understanding of what to eat. Rather, our appetites and food choices are led astray by ancient, instinctive brain circuits that play by the rules of a survival game that no longer exists. And these circuits don’t care about how you look in a bathing suit next summer. To make the case, The Hungry Brain takes readers on an eye-opening journey through cutting-edge neuroscience that has never before been available to a general audience. The Hungry Brain delivers profound insights into why the brain undermines our weight goals and transforms these insights into practical guidelines for eating well and staying slim. Along the way, it explores how the human brain works, revealing how this mysterious organ makes us who we are.




Food Components to Enhance Performance


Book Description

The physiological or psychological stresses that employees bring to their workplace affect not only their own performance but that of their co-workers and others. These stresses are often compounded by those of the job itself. Medical personnel, firefighters, police, and military personnel in combat settingsâ€"among othersâ€"experience highly unpredictable timing and types of stressors. This book reviews and comments on the performance-enhancing potential of specific food components. It reflects the views of military and non-military scientists from such fields as neuroscience, nutrition, physiology, various medical specialties, and performance psychology on the most up-to-date research available on physical and mental performance enhancement in stressful conditions. Although placed within the context of military tasks, the volume will have wide-reaching implications for individuals in any job setting.




Diet and Health


Book Description

Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.




The Role of Protein and Amino Acids in Sustaining and Enhancing Performance


Book Description

It is a commonly held belief that athletes, particularly body builders, have greater requirements for dietary protein than sedentary individuals. However, the evidence in support of this contention is controversial. This book is the latest in a series of publications designed to inform both civilian and military scientists and personnel about issues related to nutrition and military service. Among the many other stressors they experience, soldiers face unique nutritional demands during combat. Of particular concern is the role that dietary protein might play in controlling muscle mass and strength, response to injury and infection, and cognitive performance. The first part of the book contains the committee's summary of the workshop, responses to the Army's questions, conclusions, and recommendations. The remainder of the book contains papers contributed by speakers at the workshop on such topics as, the effects of aging and hormones on regulation of muscle mass and function, alterations in protein metabolism due to the stress of injury or infection, the role of individual amino acids, the components of proteins, as neurotransmitters, hormones, and modulators of various physiological processes, and the efficacy and safety considerations associated with dietary supplements aimed at enhancing performance.




The neurobiology of emotion-cognition interactions


Book Description

There is increasing interest in understanding the interplay of emotional and cognitive processes. The objective of the Research Topic was to provide an interdisciplinary survey of cutting-edge neuroscientific research on the interaction and integration of emotion and cognition in the brain. The following original empirical reports, commentaries and theoretical reviews provide a comprehensive survey on recent advances in understanding how emotional and cognitive processes interact, how they are integrated in the brain, and what their implications for understanding the mind and its disorders are. These works encompasses a broad spectrum of populations and showcases a wide variety of paradigms, measures, analytic strategies, and conceptual approaches. The aim of the Topic was to begin to address several key questions about the interplay of cognitive and emotional processes in the brain, including: what is the impact of emotional states, anxiety and stress on various cognitive functions? How are emotion and cognition integrated in the brain? Do individual differences in affective dimensions of temperament and personality alter cognitive performance, and how is this realized in the brain? Are there individual differences that increase vulnerability to the impact of affect on cognition—who is vulnerable, and who resilient? How plastic is the interplay of cognition and emotion? Taken together, these works demonstrate that emotion and cognition are deeply interwoven in the fabric of the brain, suggesting that widely held beliefs about the key constituents of ‘the emotional brain’ and ‘the cognitive brain’ are fundamentally flawed. Developing a deeper understanding of the emotional-cognitive brain is important, not just for understanding the mind but also for elucidating the root causes of its many debilitating disorders.




Molecular Aspects of Neurodegeneration, Neuroprotection, and Regeneration in Neurological Disorders


Book Description

Molecular Aspects of Neurodegeneration, Neuroprotection, and Regeneration in Neurological Disorders presents readers with comprehensive and cutting-edge information on the neurochemical mechanisms of various types of neurological disorders. The book covers information on signal transduction processes associated with neurochemistry of neurological disorders, including neurodegenerative, neurotraumatic, and neuropsychiatric disorders. The book also discusses risk factors, symptoms, pathogenesis, biomarkers, and the potential treatments of neurological disorders. The comprehensive information in this monograph may not only help in early detection of various neurological disorders, but will also promote the discovery of new drugs. - Provides a comprehensive overview of the molecular aspects of neurodegeneration, neuroprotection, and neuro-regeneration, along with therapeutic strategies for various types of neurological disorders - Provides cutting-edge research information on the signal transduction processes associated with the neurochemistry of neurological disorders - Discusses risk factors, symptoms, pathogenesis, biomarkers, and the potential for treatments of neurological disorders




Therapeutic Potentials of Curcumin for Alzheimer Disease


Book Description

This is the first book on the market that explores the importance of curcumin for the treatment of neurological disorders. It has been estimated that 35.6 million people globally had dementia in 2010 and the prevalence of dementia has been predicted to double every 20 years. Thus, 115.4 million people may be living with dementia in 2050. Alzheimer’s disease (AD) is the leading cause of dementia and is present in 60%–70% of people with dementia. Unless new discoveries are made in the prevention or treatment of AD, the number of cases in the US alone is estimated to increase threefold, to 13.2 million by the year 2050. Thus, it is important to focus on delaying and treating the onset of AD by curcumin may be an important step for controlling AD. Regular consumption of healthy diet containing curcumin enriched foods, moderate exercise, and regular sleep may produce beneficial effects not only on motor and cognitive functions, but also on memory deficits that occur to some extent during normal aging and to a large extent in AD. Delaying the onset and progression of AD and improving its symptoms by few years with regular consumption of curcumin may relieve some of the burden on health care systems. In service of this goal, this volume gives readers a comprehensive and cutting edge description of the importance of curcumin for the treatment of AD in cell culture and animal models in a manner that is useful not only to students and teachers but also to researchers, dietitians, nutritionists and physicians. It can be used as supplement text for a range of neuroscience and nutrition courses. Clinicians, neuroscientists, neurologists and pharmacologists will find this book useful for understanding molecular aspects of AD treatment by curcumin.




The Intermittent Fasting Revolution


Book Description

How intermittent fasting can enhance resilience, improve mental and physical performance, and protect against aging and disease. Most of us eat three meals a day with a smattering of snacks because we think that’s the normal, healthy way to eat. This book shows why that’s not the case. The human body and brain evolved to function well in environments where food could be obtained only intermittently. When we look at the eating patterns of our distant ancestors, we can see that an intermittent fasting eating pattern is normal—and eating three meals a day is not. In The Intermittent Fasting Revolution, prominent neuroscientist Mark Mattson shows that intermittent fasting is not only normal but also good for us; it can enhance our ability to cope with stress by making cells more resilient. It also improves mental and physical performance and protects against aging and disease. Intermittent fasting is not the latest fad diet; it doesn’t dictate food choice or quantity. It doesn’t make money for the pharmaceutical, processed food, or health care industries. Intermittent fasting is an eating pattern that includes frequent periods of time with little or negligible amounts of food. It is often accompanied by weight loss, but, Mattson says, studies show that its remarkable beneficial effects cannot be accounted for by weight loss alone. Mattson—whose pioneering research uncovered the ways that the brain responds to fasting and exercise—explains how thriving while fasting became an evolutionary adaptation. He describes the specific ways that intermittent fasting slows aging; reduces the risk of diseases, including obesity, Alzheimer’s, and diabetes; and improves both brain and body performance. He also offers practical advice on adopting an intermittent fasting eating pattern as well as information for parents and physicians.