How New Humans are Made


Book Description

In this book, when technical terminology is the only way, or the best way, to say what needs to be said, it is defined and explained - making the words a worthwhile part of what is here to be learned. --




Who We Are and How We Got Here


Book Description

The past few years have seen a revolution in our ability to map whole genome DNA from ancient humans. With the ancient DNA revolution, combined with rapid genome mapping of present human populations, has come remarkable insights into our past. This important new data has clarified and added to our knowledge from archaeology and anthropology, helped resolve long-existing controversies, challenged long-held views, and thrown up some remarkable surprises. The emerging picture is one of many waves of ancient human migrations, so that all populations existing today are mixes of ancient ones, as well as in many cases carrying a genetic component from Neanderthals, and, in some populations, Denisovans. David Reich, whose team has been at the forefront of these discoveries, explains what the genetics is telling us about ourselves and our complex and often surprising ancestry. Gone are old ideas of any kind of racial 'purity', or even deep and ancient divides between peoples. Instead, we are finding a rich variety of mixtures. Reich describes the cutting-edge findings from the past few years, and also considers the sensitivities involved in tracing ancestry, with science sometimes jostling with politics and tradition. He brings an important wider message: that we should celebrate our rich diversity, and recognize that every one of us is the result of a long history of migration and intermixing of ancient peoples, which we carry as ghosts in our DNA. What will we discover next?




Life as We Made It


Book Description

From the first dog to the first beefalo, from farming to CRISPR, the human history of remaking nature When the 2020 Nobel Prize was awarded to the inventors of CRISPR, the revolutionary gene-editing tool, it underlined our amazing and apparently novel powers to alter nature. But as biologist Beth Shapiro argues in Life as We Made It, this phenomenon isn’t new. Humans have been reshaping the world around us for ages, from early dogs to modern bacteria modified to pump out insulin. Indeed, she claims, reshaping nature—resetting the course of evolution, ours and others’—is the essence of what our species does. In exploring our evolutionary and cultural history, Shapiro finds a course for the future. If we have always been changing nature to help us survive and thrive, then we need to avoid naive arguments about how we might destroy it with our meddling, and instead ask how we can meddle better. Brilliant and insightful, Life as We Made It is an essential book for the decades to come.




Catching Fire


Book Description

In this stunningly original book, Richard Wrangham argues that it was cooking that caused the extraordinary transformation of our ancestors from apelike beings to Homo erectus. At the heart of Catching Fire lies an explosive new idea: the habit of eating cooked rather than raw food permitted the digestive tract to shrink and the human brain to grow, helped structure human society, and created the male-female division of labour. As our ancestors adapted to using fire, humans emerged as "the cooking apes". Covering everything from food-labelling and overweight pets to raw-food faddists, Catching Fire offers a startlingly original argument about how we came to be the social, intelligent, and sexual species we are today. "This notion is surprising, fresh and, in the hands of Richard Wrangham, utterly persuasive ... Big, new ideas do not come along often in evolution these days, but this is one." -Matt Ridley, author of Genome




How New Humans Are Made


Book Description

It is not okay to call something a miracle without even trying to understand it. This is human developmental biology (human embryology, in terms of cells and molecules) for everyone curious enough to see it through, from the perspective of the business of becoming human as individuals and as species; making new humans; how it happens (cells do it, ALL of it); and common variations of the process. It cannot be made quite simple and be kept quite true, but we will move as far toward simple as we can without losing touch with sound evidence. Variations from the normal version of the process, particularly malformations and twinning and chimerism, figure prominently in the story because there is no better way to learn about the usual than to study the unusual and see what differences in the endings these observable differences at the beginnings can make. In this book, when technical terminology is the only way, or the best way, to say what needs to be said, it is defined and explained making the words a worthwhile part of what is here to be learned. This book defines its own new field. We cannot claim to understand how anything human] works as human], with no effort at understanding the emergence of its form and functions. Old and new unanswered questions are waiting to be dug out from under old unquestioned answers about how becoming human unfolds. We will also address some popular and weighty, but deeply empty assertions about the circumstances and mechanisms of our beginnings and our ceaseless becoming. We will find fundamental questions from the humanities' unanswerable except from biology. Human developmental biology is a foundational discipline within the humanities.




Mapping and Sequencing the Human Genome


Book Description

There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.




How to Grow a Human


Book Description

The award-winning science writer shares “a winding romp through advances in cell biology [that] pushes readers to ponder the boundaries of life” (Science). In the summer of 2017, scientists removed a tiny piece of flesh from Philip Ball’s arm and turned it into a rudimentary “mini-brain.” The skin cells, removed from his body, did not die but were instead transformed into nerve cells that independently arranged themselves into a dense network and communicated with each other, exchanging the raw signals of thought. This was life—but whose? That disconcerting question is the focus of Philip Ball’s How to Grow a Human. In this mind-bending tour of cutting-edge cell biology, Ball shows how recent innovations could lead to tailor-made replacement organs; new medical advances for repairing damage and assisting conception; and new ways of “growing a human.” Such methods would also create new options for gene editing, with all the attendant moral dilemmas. Ball argues that these advances can never be “just about the science,” because they are already laden with a host of social narratives, preconceptions, and prejudices. But beyond even that, these developments raise provocative questions about identity and self, birth and death, and force us to ask how mutable the human body really is—and what forms it might take in years to come.




First Steps


Book Description

Winner of the W.W. Howells Book Prize from the American Anthropological Association and named one of the best science books of 2021 by Science News “DeSilva takes us on a brilliant, fun, and scientifically deep stroll through history, anatomy, and evolution, in order to illustrate the powerful story of how a particular mode of movement helped make us one of the most wonderful, dangerous and fascinating species on Earth.”—Agustín Fuentes, Professor of Anthropology, Princeton University and author of Why We Believe: Evolution and the Human Way of Being “Breezy popular science at its best. . . . Makes a compelling case overall.”—Science News Blending history, science, and culture, a stunning and highly engaging evolutionary story exploring how walking on two legs allowed humans to become the planet’s dominant species. Humans are the only mammals to walk on two, rather than four legs—a locomotion known as bipedalism. We strive to be upstanding citizens, honor those who stand tall and proud, and take a stand against injustices. We follow in each other’s footsteps and celebrate a child’s beginning to walk. But why, and how, exactly, did we take our first steps? And at what cost? Bipedalism has its drawbacks: giving birth is more difficult and dangerous; our running speed is much slower than other animals; and we suffer a variety of ailments, from hernias to sinus problems. In First Steps, paleoanthropologist Jeremy DeSilva explores how unusual and extraordinary this seemingly ordinary ability is. A seven-million-year journey to the very origins of the human lineage, First Steps shows how upright walking was a gateway to many of the other attributes that make us human—from our technological abilities, our thirst for exploration, our use of language–and may have laid the foundation for our species’ traits of compassion, empathy, and altruism. Moving from developmental psychology labs to ancient fossil sites throughout Africa and Eurasia, DeSilva brings to life our adventure walking on two legs. Delving deeply into the story of our past and the new discoveries rewriting our understanding of human evolution, First Steps examines how walking upright helped us rise above all over species on this planet. First Steps includes an eight-page color photo insert.




Lone Survivors


Book Description

A leading researcher on human evolution proposes a new and controversial theory of how our species came to be In this groundbreaking and engaging work of science, world-renowned paleoanthropologist Chris Stringer sets out a new theory of humanity's origin, challenging both the multiregionalists (who hold that modern humans developed from ancient ancestors in different parts of the world) and his own "out of Africa" theory, which maintains that humans emerged rapidly in one small part of Africa and then spread to replace all other humans within and outside the continent. Stringer's new theory, based on archeological and genetic evidence, holds that distinct humans coexisted and competed across the African continent—exchanging genes, tools, and behavioral strategies. Stringer draws on analyses of old and new fossils from around the world, DNA studies of Neanderthals (using the full genome map) and other species, and recent archeological digs to unveil his new theory. He shows how the most sensational recent fossil findings fit with his model, and he questions previous concepts (including his own) of modernity and how it evolved. Lone Survivors will be the definitive account of who and what we were, and will change perceptions about our origins and about what it means to be human.




In the Light of Evolution


Book Description

The Arthur M. Sackler Colloquia of the National Academy of Sciences address scientific topics of broad and current interest, cutting across the boundaries of traditional disciplines. Each year, four or five such colloquia are scheduled, typically two days in length and international in scope. Colloquia are organized by a member of the Academy, often with the assistance of an organizing committee, and feature presentations by leading scientists in the field and discussions with a hundred or more researchers with an interest in the topic. Colloquia presentations are recorded and posted on the National Academy of Sciences Sackler colloquia website and published on CD-ROM. These Colloquia are made possible by a generous gift from Mrs. Jill Sackler, in memory of her husband, Arthur M. Sackler.